Clinical trials: Angina, Microvascular
Metabolic Syndrome X
Effects of Dietary Proteins on Hepatic Lipid Metabolism
Individuals submitted to a high-fat or a high-fructose/sucrose diet develop, over a 6 day-period, several features of the metabolic syndrome, including increased plasma triglycerides, increased intrahepatic lipids, and decreased…
- Trial name
- NCT00558740
- Testing
- high protein intake
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Metabolic Syndrome X
Soy Protein Intake and the Metabolic Syndrome
Soy protein has a high biological value, and contains several potential health-related nutritional factors, i.e. its amino acids pattern, biological active peptides and non-protein compounds such as isoflavones.
- Trial name
- SOY (NCT01694056)
- Testing
- Soy protein diet, Control diet
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Metabolic Syndrome X
Weight Loss in Diabetic, Older Obese Adults
This study examines the effects of weight loss and aerobic exercise training on sugar metabolism and other risk factors for heart disease in obese older individuals.
- Trial name
- NCT00108329
- Testing
- Weight Loss
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Metabolic Syndrome X, Dyslipidemias
Effects of Low and Moderate Fat Diets on Lipids, Inflammation and Vascular Reactivity in the Metabolic Syndrome
The metabolic syndrome consists of five concurrent conditions which increase risk of heart disease, stroke, and diabetes. Persons with the metabolic syndrome usually have high triglyceride and low HDL levels and are overweight.
- Trial name
- NCT00362908
- Testing
- Moderate Fat and Moderate Carbohydrate Diet, Low Fat and High Carbohydrate Diet
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Washington
Metabolic Syndrome X, Infertility
Female Subfertility: a Metabolic and Vascular Profile
Introduction: Overall, 10 - 15% of couples seek specialist help once in their lives when a spontaneous pregnancy does not occur.
- Trial name
- NCT02136472
- Where
- Netherlands
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Aortic Valve Stenosis
Metabolic Determinants of the Progression of Aortic Stenosis
Calcific aortic stenosis (AS) has become the most common cardiac disease after coronary artery disease and hypertension. Unfortunately no medical therapies have been proven to decrease either the progression of valve stenosis or…
- Trial name
- PROGRESSA (NCT01679431)
- Testing
- Doppler-echocardiography, Computed tomography, Magnetic resonance imaging
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Laval University
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Metabolic Syndrome X
Exercise and Technology to Reduce Risk in a Rural Population With Metabolic Syndrome
Cardiovascular diseases are the leading cause of death among Canadians. In those with diabetes, cardiovascular complications are responsible for more than 70% of deaths.
- Trial name
- NCT01944124
- Testing
- Mobile Health, Exercise Prescription
- Where
- Canada
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Blood Pressure, Metabolic Syndrome X
Dairy Products and Metabolic Syndrome
The purpose of this trial is to investigate the effect of dairy products on the so called metabolic syndrome. Metabolic syndrome is a cluster of risk factors, such as high blood pressure and high cholesterol, for the development…
- Trial name
- NCT01913756
- Testing
- Gamalost (Norwegian traditional cheese), Gouda-type cheese
- Where
- Norway
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Life Sciences
Overweight, Metabolic Syndrome X
Impact of Chromium, Phyllanthus Emblica, and Shilajit on Cardiovascular Health, Fitness, and Weight Loss During Exercise and Diet Programs
A randomized, double-blind, placebo controlled, parallel study to determine if Chromium (Cr), Phyllanthus emblica (PE) and Shilajit (SJ) supplementation and Phyllanthus emblica fruit extract supplementation promotes greater…
- Trial name
- NCT06641596
- Testing
- Cr-400, Cr-800, PE-500
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kerry Group P.L.C
Hyperlipidemias, Metabolic Syndrome X
Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers
The aim of this study is to explore the significance of the Lys:Arg ratio on responses of lipids and lipoprotein concentrations to dietary proteins and to evaluate the effects of dietary Lys:Arg on cardiovascular disease risk…
- Conditions
- Hyperlipidemias, Metabolic Syndrome X, Cardiovascular Diseases
- Trial name
- NCT00175084
- Testing
- Comparison of dietary protein amino acid profile
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tufts University
Metabolic Syndrome X, Insulin Resistance
Oral Contraceptives in the Metabolic Syndrome
Oral contraceptives (OCs) are the most widely used method of reversible birth control. However, the long-term cardiovascular safety of the widely used low-dose OCs (ethinyl-estradiol < 50 mcg) is still debated.
- Conditions
- Metabolic Syndrome X, Insulin Resistance, Obesity, Cardiovascular Diseases
- Trial name
- NCT00205504
- Testing
- Ortho Tri Cyclen
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cardiovascular Diseases, Heart Diseases
HDL-C in Cardiac Syndrome X
High density lipoprotein cholesterol (HDL-C) is in the centrum of the process of reverse cholesterol transport from peripheral cells to the liver[10].
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Ischaemia, Unstable Angina
- Trial name
- HIRICS-X (NCT02095964)
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Dysmetabolic Iron Overload Syndrome, Metabolic Syndrome X
MEPHISTO (Macrophage Phenotype In Metabolic Syndrome With Iron Overload)
Dysmetabolic iron overload syndrome (DIOS), is a frequent hepatic iron overload associated with metabolic syndrome. We hypothesize that this mild iron overload can induce a increased macrophagic polarization towards inflammatory…
- Trial name
- MEPHISTO (NCT02066012)
- Testing
- dysmetabolic iron overload syndrome
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Insulin Resistance Syndrome X, Pancreatic Beta Cell Function
Mechanism of Fatty Acid-Induced Impairment of Glucose-Stimulated Insulin Secretion
A prolonged elevation of plasma free fatty acids (FFA) impairs glucose stimulated insulin secretion. The concept of fatty acid impairment of glucose stimulated insulin secretion (lipotoxicity) has now been well accepted.
- Trial name
- NCT00188773
- Testing
- N-acetylcysteine, intralipid, heparin
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Cardiovascular Diseases, Heart Diseases
Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease
The purpose of this study is to improve cardiovascular disease (CVD) outcomes in racial and ethnic minorities. Specifically, the study seeks to systematically characterize potential ethnic differences in obesity-related CVD by…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Metabolic Syndrome X
- Trial name
- META-HEALTH (NCT00101517)
- Where
- 2 sites in United States
- Volunteers
- 4,024 people, healthy volunteers welcome
- Sponsor
- Emory University
Metabolic Syndrome X
Comparison of Two Different Diets on Health Outcomes
The purpose of this study is to compare the effects of a low-carbohydrate diet and a high-carbohydrate, high-fiber diet, on insulin sensitivity and blood chemicals considered risk markers for heart disease, in persons with the…
- Trial name
- NCT00269646
- Testing
- Low-carbohydrate and high-carbohydrate diets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Insulin Resistance, Metabolic Syndrome X
Description of an Immune Activation Profile Linked to Insulin Resistance in Subjects Aged 55-69
The aim of the study is to describe an immune activation profile of people at risk of insulin resistance based on a wide range of markers which will allow easy identification of patients at risk.
- Trial name
- METACTIV (NCT03309761)
- Testing
- Blood test
- Where
- 2 sites in France
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Metabolic Syndrome X, Nutritional and Metabolic Diseases
Nutrition and Lifestyle Behaviour Peer Support Program Among Malaysian Adults With Metabolic Syndrome (PERSUADE)
The outlook of a community-based intervention targeting nutrition and lifestyle behaviour modification among adults with metabolic syndrome (MetS) has not been fully explored.
- Conditions
- Metabolic Syndrome X, Nutritional and Metabolic Diseases, Health Behavior
- Trial name
- PERSUADE (NCT03417128)
- Testing
- Peer support
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Monash University
Physical Activity, Endothelial Dysfunction
Recreational Physical Activity and Cardiometabolic Profile
The purpose of present study was to investigate the effect of 10 weeks of recreational physical activity program on the irisin levels, progenitor endothelial cells and cardiometabolic profile in healthy children.
- Conditions
- Physical Activity, Endothelial Dysfunction, Metabolic Syndrome x
- Trial name
- NCT02982967
- Testing
- Physical Activity
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo