Clinical trials: Angina
Coronary Arterial Disease (CAD), Angina (Stable)
Effect of Beta-blockers on Coronary Flow and Resistance in Patients With ANOCA
The goal of this clinical trial is to learn whether beta-blockers can improve coronary blood flow and reduce resistance in patients with angina and no obstructive coronary arteries (ANOCA).
- Conditions
- Coronary Arterial Disease (CAD), Angina (Stable), Microvascular Circulation
- Trial name
- BEACON (NCT06864234)
- Testing
- Saline (NaCl), Metoprolol Tartrate
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- VZW Cardiovascular Research Center Aalst
Healthy
Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets
This study will determine whether and how nitrites and nitrates in the diet affect the level of nitric oxide gas that is breathed out in air.
- Trial name
- NCT00027157
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Microvascular Disease, Cardiac Pacemaker Syndrome
The Effects of Trans Venous Cardiac Pacing on Coronary Microvascular Function and Hemodynamics
The study will examine role of transvenous pacing on coronary microcirculation.
- Trial name
- NCT03917251
- Testing
- Coronary flow and pressure measurement in patients with ventricular pacing
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Stable Angina
Downstream Molecular Signals of P2Y12 Receptors in Hyporeactive Patients Under Clopidogrel Treatment A Possible Mechanism of HOTPR(High On-Treatment Platelet Reactivity)
The investigators designed the following experiment to observe the pattern of administration in vitro, which can be completely excluded liver enzyme cytochrome P450 metabolism under the influence and observe the relevant P2Y12…
- Trial name
- NCT03190005
- Testing
- clopidogrel
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital
Syndrome X, Takotsubo Cardiomyopathy
Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X: New Insights Into the Pathophysiology
Tako-Tsubo Cardiomyopathy (TTC) and Cardiac Syndrome X (CSX) are respectively acute and chronic cardiac conditions whose clinical presentation, mimicking the onset of acute myocardial ischemia in absence of epicardial coronary…
- Trial name
- ENDAUT (NCT02307214)
- Testing
- BaroReflex Sensitivity, endothelial function measurement
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ospedale San Giovanni Bellinzona
Abdominal Aortic Aneurysm, Acute Myocardial Infarction
Body Mass Index and Initial Presentations of Cardiovascular Diseases
The association between obesity and cardiovascular disease (CVD) has mostly been studied using broad endpoints or have focused on cause-specific mortality.
- Conditions
- Abdominal Aortic Aneurysm, Acute Myocardial Infarction, Stroke, Heart Failure
- Trial name
- CALIBER (NCT01704300)
- Where
- United Kingdom
- Volunteers
- 2,240,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Myocardial Infarction, Unstable Angina
Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation
The purpose of this study is to determine whether a pre-discharge videotape introducing the concept and benefit of a Cardiac Rehabiliation \& Secondary Prevention (CRSP) program will increase intent to participate in a CRSP…
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Angioplasty, Coronary Artery Bypass Surgery
- Trial name
- NCT00372671
- Testing
- Survey, Survey and videotape
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Expansion of SCG/GCG-Based CAD Sceering: Inclusion of Healthy Controls and CCTA Patients
This study evaluates a new, non-invasive method for screening coronary artery disease (CAD) using seismocardiography (SCG) and gyrocardiography (GCG).
- Trial name
- HF-CAD-CCTA (NCT06880133)
- Testing
- Seismocardiography (SCG) and Gyrocardiography (GCG) Screening
- Where
- Uzbekistan
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Heart Force Medical Inc.
Coronary Disease, Coronary Syndrome
Prognostic Accuracy of the HEART Score in Undifferentiated Chest Pain: A Multicenter Validation Study
Chest pain remains one of the most common, potentially serious presenting complaints for adults emergency department visits with approximately 7.6 million yearly visits in the united states.
- Conditions
- Coronary Disease, Coronary Syndrome, Risk Factor, Cardiovascular, Major Adverse Cardiovascular Events
- Trial name
- NCT04580017
- Where
- 3 sites in Tunisia
- Volunteers
- 4,267 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Severe Cardiomyopathy, Angina, Unstable
Hemodynamics During the Soccer Championship 2012
The purpose of this study is to determine in soccer fans whether and to which extend positive or negative emotions during the European soccer Championship affects Central Hemodynamics, Arterial Stiffness, Heartrate and…
- Conditions
- Severe Cardiomyopathy, Angina, Unstable, Myocardial Infarction, Angina, Stable
- Trial name
- NCT01617863
- Where
- 4 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Coronary Artery Disease, Behavioral
Typical Daily Experiences, Ischemia and Repolarization in Coronary Artery Disease
The purpose of this study is to examine the role of every day experiences as they relate to coronary artery disease (CAD).
- Trial name
- NCT01531231
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Richard Lane
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms
The objective of this study is to identify Acute Coronary Syndromes (ACS) patients' specific needs and preferences for depression treatment via in-person or virtual individual interviews to (a) guide MBCT adaptation; and identify…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT03878160
- Testing
- Individual Interview
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Microvascular Angina, Microvascular Coronary Artery Disease
EUROpean Coronary microCirculatory Resistance and Absolute Flow Trial
Rationale: coronary microvascular disease is a relatively 'new' entity within the field of cardiology. The investigators are able to investigate the microcirculation by measurements performed in the catheterization laboratory.
- Conditions
- Microvascular Angina, Microvascular Coronary Artery Disease, Coronary Vasospasm, Microvascular Resistance
- Trial name
- EURO-ccraft (NCT04598308)
- Testing
- absolute flow and resistance measurements
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Coronary Artery Disease, Endothelial NO-synthase
Regulation and Signaling of Red Blood Cell (RBC) Endothelial Nitric Oxide Synthase (eNOS) in Patients With Stable and Unstable Coronary Artery Disease
The aim of this study is measurement of expression and activity of RBC eNOS in different clinical cohorts of patients with coronary artery disease and acute coronary syndrome and to investigate the importance of the NO-stimulated…
- Trial name
- NCT02265016
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Stable Angina Pectoris Associated With Depression
The Efficacy and Safety of Ginkgo Biloba Dropping Pills in the Treatment of Coronary Heart Disease With Stable Angina Pectoris and Depression
To evaluate the clinical efficacy of Ginkgo biloba dropping pills on improving the frequency of angina pectoris and the life quality of patients with stable angina pectoris and depression symptoms on the basis of the best western…
- Trial name
- NCT04529148
- Testing
- Ginkgo biloba dropping pills，best western medicine treatment, Mimetic drug of ginkgo biloba dropping pills，best western medicine treatment
- Where
- 4 sites in China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Wanbangde Pharmaceutical Group Co., LTD
Stable Angina Pectoris, Periodontitis
Effect of Periodontal Therapy on Asprosin in Stable Angina
This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis.
- Trial name
- NCT07591844
- Testing
- Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Chest Pain, Acute Coronary Syndrome
The FOVUS-ER Study: Focused Vascular Ultrasound to Risk Stratify Patients With Chest Pain in the ER
Broad Goal: To demonstrate that focused vascular ultrasound (FOVUS) can accurately risk stratify patients with chest pain in the emergency department (ED).
- Conditions
- Chest Pain, Acute Coronary Syndrome, Carotid Artery Plaque
- Trial name
- FOVUS-ER (NCT02947360)
- Testing
- Focused vascular ultrasound of the carotid arteries
- Where
- Canada
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Queen's University
Stroke, Not Specified as Hemorrhage or Infarction, Angina Pectoris
Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers
The objective of this study is to evaluate the long-term plasma and urine pharmacokinetic parameters of Cardionat®, capsules 250 mg, when used in healthy athlete volunteers. The study consists of four steps: Step 1.
- Trial name
- NCT02758912
- Testing
- оral intake of study drug capsules; study drug - Cardionat ® (trimethylhydrazinium propionate dihydrate), oral capsules 250 mg
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Dyslipidemia, Angina (Stable)
Validation of Remote Photoplethysmography (rPPG)-Derived Cardiovascular Parameters Against Standard Clinical Measurements and Risk Scores in a Community
The goal of this observational study is to evaluate whether a contactless camera-based technology, called remote photoplethysmography (rPPG), can accurately measure cardiovascular parameters and estimate cardiovascular risk in…
- Conditions
- Dyslipidemia, Angina (Stable), Coronary Artery Disease (CAD), Heart Disease
- Trial name
- NCT07502703
- Where
- Indonesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Angina Pectoris, Coronary Artery Disease
Effects of Integrated Treatment by Traditional Chinese and Western Medicine in Reducing Cardiovascular Events
Compared with standardized western medical drug therapy, this study is mainly about whether the combination of standardized western medical drug therapy and Chinese medical continued treatment, can further decrease the rate of…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Coronary Disease, Heart Disease
- Trial name
- NCT01715376
- Where
- China
- Volunteers
- 1,042 people, healthy volunteers welcome
- Sponsor
- Changchun University of Chinese Medicine