Clinical trials: Anginal Pain
Coronary Syndrome
Identification of Biomarkers in Subjects With Coronary Syndrome (PLAQUE Study)
The study will to test the levels of innovative biomarkers, such as miRNAs, in the blood of subjects underwent to angioplasty procedure according to standard clinical practice.
- Trial name
- PLAQUE (NCT06103357)
- Testing
- blood sample collection
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Angina
A TSHRN1201 Sub-study-To Evaluate the Effects of add-on Ranolazine on Exercise Tolerance and Angina Frequency
This is a double-blind, randomized, placebo-controlled, and parallel study. The study is comprised of three main phases: a single-blind placebo run-in qualifying phase lasting about 14 days, a double-blind treatment phase of 12…
- Trial name
- NCT03401502
- Testing
- Ranolazine
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- TSH Biopharm Corporation Limited
Acute Coronary Syndrome
A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects
This study will evaluate the relative efficacy and safety of prasugrel and clopidogrel in a medically managed Unstable Angina/Non-ST-Elevation Myocardial Infarction (UA/NSTEMI) acute coronary syndrome (ACS) population (that is…
- Trial name
- TRILOGY ACS (NCT00699998)
- Testing
- Clopidogrel, Prasugrel, Commercially-available Aspirin
- Where
- 688 sites in United States, Argentina and 51 more
- Volunteers
- 9,326 people
- Sponsor
- Eli Lilly and Company
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Barriers Limiting OCT Penetration in Clinical Practice
The updated guidelines from the European Society of Cardiology (ESC) for chronic coronary syndrome (CCS) have upgraded the use of IVUS and OCT to a class IA recommendation for complex PCI, based on evidence showing a reduction in…
- Trial name
- OCT2ACT (NCT07193693)
- Where
- 2 sites in Italy
- Volunteers
- 1,189 people
- Sponsor
- Consorzio Futuro in Ricerca
Coronary Artery Disease, Angina Pectoris
DUrable Polymer-based STent CHallenge of Promus ElemEnt Versus ReSolute Integrity
Rationale: The introduction of drug-eluting stents (DES) in the treatment of coronary artery disease has led to a significant reduction in morbidity but there are further demands on DES performance.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Unstable Angina Pectoris, Acute Coronary Syndrome
- Trial name
- DUTCHPEERS (NCT02175706)
- Testing
- Resolute Integrity®, Promus Element®
- Where
- 4 sites in Netherlands
- Volunteers
- 1,811 people
- Sponsor
- Thorax Centrum Twente
Ischemic Heart Disease
Randomized Clinical Comparison of the Endeavor and the Cypher Coronary Stents in Non-selected Angina Pectoris Patients
Randomized clinical comparison of the serolimus eluting Cypher stent and the zotarolimus eluting Endeavor stent.
- Trial name
- SORT-OUTIII (NCT00660478)
- Testing
- Endeavor, Cypher Select
- Where
- Denmark
- Volunteers
- 2,342 people
- Sponsor
- Evald Hoej Christiansen
Acute Myocardial Infarction, Percutaneous Coronary Intervention
Enhancing Cardiac Rehabilitation Through Behavioral Nudges
Adherence to cardiac rehabilitation is poor, and worse for minorities, women, and those with lower levels of education. Patients less likely to be referred to and complete cardiac rehab are at highest risk of adverse outcomes and…
- Conditions
- Acute Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Disease, Valvular Disease
- Trial name
- NCT03834155
- Testing
- Hospital-based CR + Movn Application, Choice of Hospital or home-based CR + Movn Application, Hospital-based CR + Movn Application + Nudge
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Denver Health and Hospital Authority
Chronic Stable Angina Pectoris
A Study on the Microcirculatory Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04041206
- Testing
- Laser doppler
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Refractory Angina Pectoris
Extracorporeal Shockwave Therapy for the Treatment of Chronic Angina Pectoris
Low intensity shockwaves have been proven in animal studies to induce local growth of new blood vessels from existing ones. The hypothesis of this study is that shockwave therapy could improve the symptoms of patients with…
- Trial name
- NCT01567592
- Testing
- Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Medispec
Angina
Effectiveness of Ranolazine on Reducing Chest Pain in Patients With Blockage But no Stents
To determine if ranolazine improves angina symptoms at 4 months compared with placebo among patients who are deferred for receiving a Percutaneous Coronary Intervention (PCI) based on the Fractional Flow Reserve (FFR) measurement.
- Trial name
- IMWELL3 (NCT02147834)
- Testing
- Ranolazine, Sugar pill
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- North Florida Foundation for Research and Education
Angina, Unstable, Angioplasty, Transluminal, Percutaneous Coronary
A Study Evaluating the Efficacy and Safety of Abciximab, an Anti-platelet Therapy, in Patients Undergoing High-risk Coronary Angioplasty
The purpose of this study is to evaluate the effectiveness and safety of abciximab (an anti-platelet therapy) versus placebo in patients undergoing high risk coronary angioplasty.
- Trial name
- NCT00269893
- Testing
- Abciximab
- Volunteers
- 2,038 people
- Sponsor
- Centocor, Inc.
Stable Angina Pectoris, Unstable Angina Pectoris
PCB for Long De Novo Lesions of Main Coronary Arteries (D-Lesion Long Trial)
This study evaluates the Efficacy and Safety of Paclitaxel-Coated Balloon Catheter in Patients With Diffuse Long De Novo Lesions of Main Coronary Arteries.
- Trial name
- NCT03155971
- Testing
- Paclitaxel-Coated Balloon
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The People's Hospital of Liaoning Province
Ventricular Tachycardia, Coronary Artery Disease
Coronary Flow During Rapid Heart Rates
The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are: 1.
- Conditions
- Ventricular Tachycardia, Coronary Artery Disease, Heart Failure, Coronary Microvascular Dysfunction
- Trial name
- VT flow (NCT05841199)
- Testing
- Pressure and flow measurement during simulated VT
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Imperial College London
Arterial Occlusion, Angina Pectoris
Comparing TR Band to Statseal in Conjunction With TR Band
The primary objectives of this study are to evaluate the performance of StatSeal Advanced used in conjunction with the TR Band (SSA) as compared to the TR Band without SSA (TRB) relative to: the incidence of peri-procedural…
- Conditions
- Arterial Occlusion, Angina Pectoris, Cardiovascular Diseases, Atherosclerosis
- Trial name
- NCT03028025
- Testing
- StatSeal, TR Band
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- VA Long Beach Healthcare System
Acute Coronary Syndrome, Myocardial Ischemia
Safety and Efficacy of Ticagrelor Versus Clopidogrel in Asian/KOREAn Patients With Acute Coronary Syndromes Intended for Invasive Management
The purpose of this study is to assess safety and efficacy of Ticagrelor versus Clopidogrel in Asian/KOREAn patients with acute coronary syndromes intended for invasive management.
- Conditions
- Acute Coronary Syndrome, Myocardial Ischemia, Heart Diseases, Cardiovascular Diseases
- Trial name
- TICA KOREA (NCT02094963)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 10 sites in South Korea
- Volunteers
- 800 people
- Sponsor
- Seung-Jung Park
Stable Angina, Unstable Angina
RRISC Study: Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent.
Context: Sirolimus-eluting-stents have improved the benefits of percutaneous interventions in native coronary arteries reducing the occurrence of restenosis and repeated revascularization, however saphenous vein grafts have been…
- Conditions
- Stable Angina, Unstable Angina, Coronary Artery Disease, Saphenous Vein Graft Disease
- Trial name
- NCT00263263
- Testing
- sirolimus-eluting stent, bare metal stent
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- Antwerp Cardiovascular Institute Middelheim
Coronary Artery Bypass Surgery, Stable Angina
Optimal Dose of Acetylsalicylic Acid After Coronary Artery Bypass Grafting
This is a single-center, open-label, randomized controlled trial. Patients with stable angina pectoris without use of dual antiplatelet therapy or anticoagulation therapy scheduled for coronary artery bypass grafting (CABG) at…
- Trial name
- NCT02482857
- Testing
- Acetylsalicylic acid
- Volunteers
- 45 people
- Sponsor
- Karolinska University Hospital
Myocardial Infarction, Stable Angina
Readiness for Behavior Change After a Heart Attack
The purpose of this study is to test if an early appointment (within 10 days) when compared to a standard appointment (5 weeks) will affect attendance at the Cardiac Rehabilitation orientation and subsequent enrollment into…
- Conditions
- Myocardial Infarction, Stable Angina, Coronary Artery Disease
- Trial name
- ENROLL (NCT01596036)
- Testing
- Early appointment (within 10 days), Routine referral (at 5 weeks)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Stable Angina, Metabolic Syndrome
Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome
The purpose of this study is to determine the effects of ranolazine on different markers of cardiometabolic disease in women with stable angina.
- Trial name
- IRMA (NCT02252406)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Florida
Acute Coronary Syndrome
Vaccination Against Influenza to Prevent Cardiovascular Events After Acute Coronary Syndromes
Cardiovascular disease has a great burden in the context of public health, as well as the low pharmacological adherence of patients who have chronic non-transmissible diseases.
- Trial name
- VIP-ACS (NCT04001504)
- Testing
- Double Dose Quadrivalent Influenza Vaccine, Standard Dose Quadrivalent Influenza Vaccine
- Where
- 22 sites in Brazil
- Volunteers
- 1,801 people
- Sponsor
- Hospital Israelita Albert Einstein
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