Clinical trials: Angiogram
Coronary Artery Disease
Saphenous Vein as Y-composite Versus Aortocoronary Conduit for CABG
Left internal thoracic artery (LITA) has been acknowledged as the first graft of choice for coronary artery bypass grafting (CABG).
- Trial name
- CONFIG2 (NCT05704296)
- Testing
- Y-composite grafting, Aortocoronary grafting
- Where
- South Korea
- Volunteers
- 290 people
- Sponsor
- Ho Young Hwang
Ischemic Heart Disease
Multicenter Registry for Angiography-Derived Quantitative Flow Ratio
1. to investigate the feasibility and diagnostic performance of contrast quantitative flow ratio (QFR) for identifying the functional significance of intermediate degree stenotic lesions in all-comer patients with coronary artery…
- Trial name
- QFRRegistry (NCT03791788)
- Testing
- QFR assessment
- Where
- 5 sites in South Korea
- Volunteers
- 524 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome
STEMI Versus NSTEMI: Clinical and Angiographic Differences
The purpose of this study is to assess differences in the risk profile and in the coronary angiographic presentation between STEMI and NSTEMI.
- Trial name
- NCT01636427
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Coronary Artery Disease
Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison
The main purpose of this study is to compare myocardial perfusion imaging using Rubidium-82 PET with Tc-99m-MIBI SPET, in the evaluation of significant Coronary Artery Disease (CAD).
- Trial name
- NCT01379677
- Testing
- Rubidium-82, Sestamibi. reconstitution with sodium pertechnetate (99mTc)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Advanced Accelerator Applications
Angina, Stable
Method of Clopidogrel Pre-treatment Undergoing Conventional Coronary Angiogram in Angina Patients
The study included 511 patients who underwent PCI because of angina during 2010-2011 at three Korean hospitals. Clopidogrel-naïve patients received either a loading dose (LD; 600 mg at 2-24 h before the procedure) or routine…
- Trial name
- MECCA (NCT03759067)
- Testing
- clopidogrel 75mg, Clopidogrel 300 mg, clopidogrel 600mg
- Volunteers
- 511 people
- Sponsor
- Korea University Anam Hospital
Enlarged Prostate
3D Rotational CT Angiogram With Embolization Guidance and CBCT in Prostatic Artery Embolization
The purpose of this research study is to learn about how cone-beam Computerized Tomography scans (X-ray images taken from different angles) work together with an embolization guidance software (helps the doctor see the arteries…
- Trial name
- NCT03164629
- Testing
- cone-beam CT 3D Emboguide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Vascular Calcification* / Diagnostic Imaging, Atherectomies, Coronary
Calcium Reduction by Orbital Atherectomy in Western Europe
In calcified lesions, optimal stent placement and expansion may prove to be challenging. Lesion preparation is necessary to facilitate optimal stenting in calcified lesions, for which orbital atherectomy can used.
- Conditions
- Vascular Calcification* / Diagnostic Imaging, Atherectomies, Coronary, Tomography, Optical Coherence, Coronary Intervention, Percutaneous
- Trial name
- CROWN (NCT06035783)
- Testing
- Orbital Atherectomy
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Erasmus Medical Center
Acute Ischemic Stroke
C-arm Cone Beam CT Perfusion Guided Cerebrovascular Interventions
The overarching objective of our proposal is to develop a One-Stop-Shop imaging using the available C-arm Cone-Beam Computed Tomography (CBCT) data acquisition systems currently widely available worldwide in interventional…
- Trial name
- NCT03232151
- Testing
- C-Arm Cone Beam Computed Tomography
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Wisconsin, Madison
Colorectal Disease Requiring Elective Laparoscopic Resection, Colorectal Anastomotic Leak
ICG Fluorescence Angiography to Reduce Anastomotic Leak After Laparoscopic Colorectal Resection
This prospective randomized controlled trial evaluates whether intraoperative indocyanine green (ICG) fluorescence angiography reduces clinically significant anastomotic leakage after elective laparoscopic colorectal resection…
- Trial name
- NCT07826156
- Testing
- Visual assessment, ICG visuals assessment
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Contrast-induced Nephropathy
Comparison of Captisol-Enabled™ Iohexol and Omnipaque™ in Patients With Impaired Renal Function Undergoing Coronary Angiography
Randomized parallel group study comparing the renal safety of Captisol-Enabled™ Iohexol (CE-Iohexol) Injection and Omnipaque™ (Iohexol) Injection in patients with impaired renal function undergoing coronary angiography.
- Trial name
- NCT04627831
- Testing
- CE-Iohexol, Iohexol
- Sponsor
- Ligand Pharmaceuticals
Coronary Artery Disease
Correlation of Biomarkers With the Presence and Severity of Coronary Artery Disease
The development of coronary artery disease is multifactorial. Peripheral blood biomarkers paly an important role in the prediction of coronary artery disease.
- Trial name
- PREDICTION-NJ (NCT05015270)
- Testing
- Medications or percutaneous coronary intervention
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
To Assess the Feasibility of CT-derived FFR, WSS and TPF on Coronary Atherosclerotic Plaque
Evaluation of FFR, WSS, and TPF Using CCTA
To assess the feasibility of CT-derived computed fractional flow reserve (FFRCT), wall shear stress and total plaque force on coronary atherosclerotic plaque and to collect the preliminary data to apply those parameters for the…
- Trial name
- NCT01857687
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Macular Holes, Optical Coherence Tomography
Optical Coherence Tomography Angiography Characteristics of Patients With Surgically Closed Full-thickness Idiopathic Macular Holes < 600 μm With Air Versus 10% SF6 Tamponade
State of the art treatment for idiopathic macular holes consists of pars plana vitrectomy, internal limiting membrane staining with a blue colouring dye, internal limiting membrane peeling and filling of the vitrectomized space…
- Trial name
- NCT05223205
- Testing
- Air, 10% SF6 and 90% air
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz
Diagnosis Coronary Artery Disease
Diagnostic Performances of Computed TomographIc Coronary Angiography and Intravascular Ultrasound
Diagnostic purposes of the coronary angiography is to detect stenosis (anatomy) and to detect ischemia related stenosis (function). Coronary angiography (CAG) is a gold standard invasive techniques, but has several limitations.
- Trial name
- IMAGES-FFR (NCT01400230)
- Testing
- diagnostic procedures CCTA, CAG, IVUS and FFR
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Contrast Medium-induced Nephropathy
Prevention of Contrast Renal Injury With Different Hydration Strategies
Using a randomized controlled trial design, two hydration protocols for the prevention of contrast medium-induced nephropathy will be tested.
- Trial name
- POSEIDON (NCT01218828)
- Testing
- LVEDP -Based hydration strategy, Standard hydration
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Kaiser Permanente
Glaucoma; Drugs, Normal Tension Glaucoma
Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study
This study evaluates the possible acute changes in peripapillary blood flow after instillation of antiglaucoma medications in patients with primary open angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension…
- Conditions
- Glaucoma; Drugs, Normal Tension Glaucoma, Primary Open-angle Glaucoma
- Trial name
- NCT03323164
- Testing
- Timolol Maleate, Brimonidine Tartrate
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Wills Eye
Peripheral Arterial Occlusive Disease
Pilot Study to Compare ISOVUE®-250 and VISIPAQUE™ 270 for Motion Artifact and Pain in Peripheral DSA
The purpose of this study is to compare ISOVUE-250 and VISIPAQUE 270 for motion artifact and pain following intraarterial injection for peripheral DSA.
- Trial name
- NCT00740207
- Testing
- VISIPAQUE 270, Isovue 250
- Volunteers
- 33 people
- Sponsor
- Bracco Diagnostics, Inc
Angina Pectoris, Acute Myocardial Infarction
Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome
Previous trials have demonstrated that the use of physiological assessment of stenosis severity using fractional flow reserve (FFR) is superior to angiographic assessment in percutaneous coronary intervention (PCI) and improves…
- Trial name
- iFR Swedeheart (NCT02166736)
- Testing
- iFR, FFR
- Where
- 14 sites in Denmark, Iceland and 1 more
- Volunteers
- 2,037 people
- Sponsor
- Uppsala University
Vascular Access Complication, Radial Artery
Feasibility and Safety of the Routine Distal Transradial Approach
The distal transradial approach (dTRA) via the anatomical snuffbox is hypothesized to be more beneficial than the conventional transradial access (cTRA) in patients undergoing coronary procedures.
- Conditions
- Vascular Access Complication, Radial Artery, Coronary Artery Disease, Puncture
- Trial name
- ANTARES (NCT05982366)
- Testing
- distal radial artery acess side, conventional radial artery acess side
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Łukasz Koziński
Contrast Induced Acute Kidney Injury
Monitoring Renal Blood Flow With Contrast Enhanced Ultrasound During Coronary Angiogram
Contrast induced nephropathy (CN) is a common cause of acute kidney injury and is associated with increased morbidity and mortality and healthcare cost.
- Trial name
- NCT01544036
- Testing
- perflutren
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
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