Clinical trials: Angioplasty, Transluminal, Percutaneous Coronary
Coronary Artery Disease, Coronary Occlusion
Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Total Occlusions
The purpose of this study is to investigate the safety and efficacy of drug-coated balloon angioplasty for the treatment of chronic total occlusions patients with chronic total occlusion (CTO) lesion.
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention, Chronic Total Occlusion of Coronary Artery
- Trial name
- NCT04744571
- Testing
- aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor, coronary wires. or coronary balloons, drug-coated balloon
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis
ECLIPSE Feasibility Trial (Ensure's Vascular Closure Device Speeds Hemostasis Trial) EU
To assess the safety and feasibility of the 7F Ensure Medical Vascular Closure Devices to facilitate hemostasis in patients undergoing diagnostic or interventional procedures.
- Trial name
- ECLIPSE (NCT00574691)
- Testing
- 7F Ensure Medical Vascular Closure Device
- Where
- Germany
- Volunteers
- 93 people
- Sponsor
- Cordis US Corp.
Acute Coronary Syndrome
Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome
The purpose of this study is to determine if testing patients for endothelial dysfunction will help identify which patients are more likely at risk to have another heart attack in the future.
- Trial name
- NCT01500902
- Testing
- EndoPAT testing (non invasive device), WatchPAT testing (non-invasive device)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Mayo Clinic
Coronary Disease, Hypercholesterolemia
Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS)
The purpose of this study is to compare the effects of pitavastatin and atorvastatin on coronary plaque volume in patients with acute coronary syndrome and to clarify the relationship between coronary plaque volume, serum lipids…
- Trial name
- NCT00242944
- Testing
- Pitavastatin, Atorvastatin
- Where
- 3 sites in Japan
- Volunteers
- 307 people
- Sponsor
- Kyoto University
Coronary Artery Disease, Angioplasty, Transluminal, Percutaneous Coronary
Safety Study to Assess the FEasibility of Use of the TRYTON Bifurcation Coronary Stent System (SAFE-TRY)
To assess the safety and feasibility of the use of the Tryton bifurcation coronary stent system for the treatment of single de novo bifurcation lesions in native coronary arteries.
- Trial name
- SAFE-TRY (NCT01174433)
- Testing
- Tryton
- Where
- 6 sites in Italy
- Volunteers
- 241 people
- Sponsor
- University of Padova
Myocardial Infarction, Stem Cell Transplantation
Strengthening Transplantation Effects of Bone Marrow Mononuclear Cells With Atorvastatin in Myocardial Infarction
The benefit of current stem cell transplantation therapy for myocardial infarction is limited by low survival rate for stem cell.
- Conditions
- Myocardial Infarction, Stem Cell Transplantation, Angioplasty, Transluminal, Percutaneous Coronary
- Trial name
- STEM-AMI (NCT00979758)
- Testing
- Atorvastatin and mononuclear cells transplantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Acute Coronary Syndrome, Myocardial Infarction
Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)
The purpose of the COGENT-1 clinical trial is to determine whether CGT-2168 (clopidogrel and omeprazole) compared to clopidogrel is safe and effective in reducing the incidence of gastrointestinal bleeding and symptomatic ulcer…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- COGENT-1 (NCT00557921)
- Testing
- CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin, Plavix (clopidogrel 75 mg) and aspirin
- Where
- 491 sites in United States, Australia and 14 more
- Volunteers
- 5,000 people
- Sponsor
- Cogentus Pharmaceuticals
Coronary Artery Disease
The Stent or Surgery (SoS) Trial
This study compared two different methods of restoring blood flow to the heart when there has been a narrowing or blockage in the blood vessels that supply the heart.
- Trial name
- NCT00475449
- Testing
- percutaneous coronary intervention, coronary artery bypass grafting
- Volunteers
- 988 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Myocardial Infarction, Angioplasty, Transluminal, Percutaneous Coronary
Arterial Access for Coronary Intervention in Myocardial Infarction
The aim of this study is to compare the radial and femoral access for percutaneous interventions in the acute phase of the ST elevation acute myocardial infarction in terms of efficacy and security.
- Conditions
- Myocardial Infarction, Angioplasty, Transluminal, Percutaneous Coronary, Myocardial Reperfusion
- Trial name
- NCT00356044
- Testing
- Coronary angioplasty
- Where
- 3 sites in Spain
- Volunteers
- 439 people
- Sponsor
- Hospital Juan Canalejo
In-Stent Restenosis
Treatment of Drug-eluting Stent (DES) In-Stent Restenosis With SeQuent® Please Paclitaxel Eluting Percutaneous Transluminal Coronary Angioplasty (PTCA) Catheter
The aim of the study is to assess the efficacy of the Paclitaxel-eluting PTCA - balloon catheter SeQuent® Please to treat in-stent restenoses (ISR) of various drug eluting stents in native coronary arteries with reference…
- Trial name
- NCT00998439
- Testing
- SeQuent® Please, SeQuent® II
- Where
- 8 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Klinikum Coburg
Angioplasty, Transluminal, Percutaneous Coronary
A Study Comparing the Efficacy and Safety of Abciximab, an Anti-Platelet Therapy, in Combination With Two Different Heparin Regimens in Patients Undergoing Percutaneous Coronary Intervention.
The purpose of this study is to compare the safety and effectiveness of abciximab, an anti-platelet therapy, versus placebo in patients undergoing percutaneous coronary intervention when administered in combination with two…
- Trial name
- NCT00269880
- Testing
- Heparin, Abciximab
- Volunteers
- 2,792 people
- Sponsor
- Centocor, Inc.
Coronary Artery Disease, Atherosclerosis, Coronary
HIV Infection And Evolvement of Atherosclerotic Plaque
In a prospective multi-center observational study, 200 HIV-infected patients treated with antiretroviral treatment (ART) and who suffered from coronary artery disease (CAD) will be enrolled.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Coronary, Hiv, HIV Infections
- Trial name
- HIVE (NCT04810364)
- Testing
- Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 2 sites in Russia
- Volunteers
- 1,000 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Coronary Disease
Randomized Trial of Coronary Angioplasty for de Novo Lesions in sMall vesSElS With Drug Eluting Balloon.
Significant lesions in small coronary arteries are frequently found (35%-50%) in patients with coronary artery disease. Independently of the type of coronary angioplasty the restenosis and the need for repeat revascularization…
- Trial name
- RAMSES (NCT01722799)
- Testing
- Drug elluting Balloon (DEB), Drug elluting coronary stent (DES)
- Where
- Spain
- Volunteers
- 97 people
- Sponsor
- Andres Iñiguez Romo, MD, PhD
Bioresorbable Scaffolds
Performance of Bioabsorbable Vascular Scaffolds (Absorb) Compared to Xience Stents - an Optical Coherence Tomography Study
The biodegradable ABSORB scaffold is characterized by a greater strut thickness, but it has a greater flexibility compared to the XIENCE stent.
- Trial name
- NCT02001025
- Testing
- Absorb scaffold, Xience stent
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Rudolf Berger
Angioplasty
The Paclitaxel-Eluting Percutaneous Coronary Angioplasty (PTCA)-Balloon Catheter for the Treatment of Coronary Bifurcations
The intention of this trial is to assess the safety and efficacy of Drug Eluting Balloon (DEB) application (SeQuent Please) to the side branch in percutaneous coronary intervention (PCI) of Medina 0,0,1 coronary bifurcation…
- Trial name
- PEPCAD-BIF (NCT01180517)
- Testing
- Percutaneous coronary intervention (PCI), PCI
- Where
- 2 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Ralf Degenhardt, PhD
Stable Angina Pectoris, Ad Hoc Percutaneous Coronary Intervention
Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity
The purpose of the study is to determine whether administration of 150 mg clopidogrel is effective in reducing the one-year incidence of thromboischemic events in patients with high on-clopidogrel platelet reactivity compared to…
- Trial name
- DOSER (NCT00638326)
- Testing
- clopidogrel
- Where
- Hungary
- Volunteers
- 500 people
- Sponsor
- University of Pecs
Acute Coronary Syndrome, Angioplasty, Transluminal, Percutaneous Coronary
Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions
The central hypothesis for this work is that platelet - leukocyte interactions play a critical role in the pathogenesis of acute ischemic events.
- Conditions
- Acute Coronary Syndrome, Angioplasty, Transluminal, Percutaneous Coronary, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Blood Platelets
- Trial name
- NCT01241903
- Testing
- rosuvastatin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Susan Smyth
Renovascular Hypertension, Renovascular Hypertension With Renal Failure
Effects of Percutaneous Transluminal Renal Angioplasty of Atherosclerotic Renal Artery Stenosis in High-Risk Patients.
The goal of this clinical trial is to document a beneficial effect of percutaneous transluminal renal angioplasty (PTRA) of atherosclerotic renal artery stenosis in high-risk patients selected according to the criteria used in…
- Conditions
- Renovascular Hypertension, Renovascular Hypertension With Renal Failure, Heart Failure, Renal Artery Stenosis Atherosclerotic
- Trial name
- DAN-PTRAII (NCT05834803)
- Testing
- Optimal medical therapy (OMT), Catheter-based angiography, Measurement of translesional pressure gradients
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Acute Coronary Syndrome
ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-3 Study
The purpose of this study is to explore the benefit of the prasugrel monotherapy without aspirin as compared with the 1-month dual therapy with aspirin and prasugrel in terms of reducing bleeding events after percutaneous…
- Trial name
- STOPDAPT-3 (NCT04609111)
- Testing
- No aspirin, 1-month DAPT
- Where
- Japan
- Volunteers
- 6,002 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Coronary Artery Disease
Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion?
We sought to evaluate the long-term safety and efficacy of drug-eluting stent in large vessels compared with bare metal stent.
- Trial name
- COPE (NCT00852215)
- Testing
- Taxus stent, Vision stent
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center