Clinical trials: Angioplasty Patients
Carotid Artery Disease
SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy
The primary objective of this study is to assess the outcomes of stenting with distal protection in the treatment of obstructive carotid artery disease.
- Trial name
- NCT00403078
- Where
- 5 sites in United States
- Volunteers
- 21,008 people
- Sponsor
- Cordis US Corp.
Antiplatelet Drug, Acute Coronary Syndrome
1-month DAPT Plus 5-month Ticagrelor Monotherapy Versus 12-month DAPT in Patients With Drug-coated Balloon
Drug-Coated Balloon (DCB) angioplasty is similar to plain old balloon angioplasty procedurally, but there is an anti-proliferative medication paclitaxel coated to the balloon.
- Conditions
- Antiplatelet Drug, Acute Coronary Syndrome, Angioplasty, Balloon
- Trial name
- CAGEFREEII (NCT04971356)
- Testing
- Aspirin 100mg for 1-month (immediately after PCI), Ticagrelor 90mg for 6-month (immediately after PCI), Aspirin 100mg for 6-month (6-month post PCI)
- Where
- China
- Volunteers
- 1,948 people
- Sponsor
- Xijing Hospital
Coronary Stenosis Treated With Implant of Bioresorbable Devices
Costs, Effectiveness, QALYs, and Efficiency of Bioabsorbable Devices in Daily Clinical Practice
A multicenter, prospective, observational cohort study with clinical, quality of life, and economic evaluation to ascertain the quality-adjusted life years (QALYs) gained by patients with ischemic heart disease revascularized…
- Trial name
- REPARA-QALY (NCT02854007)
- Testing
- Coronary angioplasty with implant of bioresorbable device
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Sección Hemodinamica y Cardiologia Intervencionista
Peripheral Artery Disease
Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease
This study is a prospective, interventional, multicenter 1:1 randomized trial. The trial evaluates the safety and efficacy of the Magic Touch PTA sirolimus drug-coated balloon in comparison to the treatment with POBA (control…
- Trial name
- LIMES (NCT04772300)
- Testing
- Percutaneous Transluminal Angioplasty (PTA) MagicTouch Sirolimus Coated PTA Balloon Catheter, Percutaneous Transluminal Angioplasty (PTA) with non-coated balloon catheter (POBA)
- Where
- 19 sites in Austria, Germany
- Volunteers
- 230 people
- Sponsor
- Jena University Hospital
Cronic Limb Ishemia, Intervention
Balloon Angioplasty Versus Xpert Stent in CLI Patients XXS Study
This study is an investigator-initiated study. The study will be performed as a prospective, randomized, controlled multi-center trial to evaluate the safety and efficiency of Xpert stents compared to PTA in patients with chronic…
- Trial name
- XXS (NCT00546845)
- Testing
- Balloon angioplasty, Use of self-expanding Expert stent
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital Tuebingen
Myocardial Infarction
Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction
The primary objectives of the trial are: 1. To establish the safety and efficacy of the use of bivalirudin (+ bail-out GP IIb/IIIa inhibitors) compared to the use of unfractionated heparin + GP IIb/IIIa inhibitors in patients…
- Trial name
- NCT00433966
- Testing
- Bivalirudin, Unfractionated heparin, Bare metal stent
- Where
- United States
- Volunteers
- 3,602 people
- Sponsor
- Cardiovascular Research Foundation, New York
Acute Myocardial Infarction
Erythropoietin in Acute Myocardial Infarction
Erythropoietin (EPO) is a naturally occuring hormone which regulates the body's response to lack of oxygen and controls the number of red cells in the blood.
- Trial name
- NCT00149058
- Testing
- Erythropoietin
- Where
- 2 sites in United Kingdom
- Volunteers
- 124 people
- Sponsor
- Hammersmith Hospitals NHS Trust
Carotid Stenosis
Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting
The purpose of this study is to evaluate the safety and efficacy of the TriActiv® ProGuard™ System when used during a stent placement in a blockage within the carotid artery in patients considered to be at high risk for…
- Trial name
- NCT00395785
- Testing
- Carotid Stent Implantation, Embolic Protection
- Where
- 34 sites in United States, Germany
- Volunteers
- 400 people
- Sponsor
- Kensey Nash Corporation
Ischemia
Evaluation of Paclitaxel in Patients With CLI and Femoropopliteal Occlusive Disease Treated With DCB Angioplasty
The use of drug coated balloon (DCB) in patients with critical limb ischemia (CLI) and tissue loss has recently raised some concerns after the IN.PACT deep trial using paclitaxel coated balloon angioplasty in the tibial arteries…
- Trial name
- NCT02758847
- Testing
- Angiogram, Medtronic DCB (paclitaxel)/stent, Angiogram, Bard DCB (paclitaxel)/stent
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rabih A. Chaer
Acute Myocardial Infarction
Primary Angioplasty for Acute Myocardial Infarction in Patients With Symptom Duration Above 12 Hours
Background: Acute balloon angioplasty is beneficial in patients with acute myocardial infarction. However, presently this treatment is not offered to patients with symptom duration above 12 hours.
- Trial name
- NCT00260416
- Testing
- Primary angioplasty with stent and abciximab
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease
Angioplasty of Left Main - lAriboisiere Registry
In patients with unprotected left main disease (ULMD), angioplasty is emerging as an alternative technique. The investigators aimed to determine the rate of major cardiovascular events in patients treated by angioplasty for ULMD…
- Trial name
- ALMA (NCT01725373)
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Hopital Lariboisière
Сhronic Ischemia of the Lower Extremities, Atherosclerosis of the Tibial Arteries
Angioplasty of the Tibial Arteries Augmented Radio Frequency Denervation of the Popliteal Artery
Angioplasty augmented radiofrequency denervation popliteal artery, in our opinion, will remove the spasm with macro and microcirculatory blood flow, which increases revascularization patency of tibial arteries.
- Conditions
- Сhronic Ischemia of the Lower Extremities, Atherosclerosis of the Tibial Arteries, Lesion no More Than Two Tibial Arteries, Steno-occlusive Lesion of the Tibial Arteries
- Trial name
- ATRFPA (NCT02825446)
- Testing
- angioplasty tibial arteries, angioplasty tibial arteries augmented radio frequency denervation popliteal artery by the use"Vessix Renal Denervation System Balloon"
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Multiple Sclerosis
Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients
This is a single center, multispecialty, randomized double blind placebo control feasibility clinical trial. The purpose is to evaluate the safety, feasibility and efficacy of percutaneous transluminal angioplasty in treating…
- Trial name
- NCT01089686
- Testing
- Venoplasty
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Manish Mehta, MD
Coronary Artery Lesions With Implantation of Coronary Device
REPARA Study: REgistry of PAtients With bioResorbable Device in Daily Clinical prActice
A multicentre, observational, prospective device registry, with no control group, designed to evaluate the efficacy and safety of the bioresorbable coronary device, used according to the indications of use, in daily clinical…
- Trial name
- REPARA (NCT02256449)
- Where
- Spain
- Volunteers
- 2,440 people
- Sponsor
- Sección Hemodinamica y Cardiologia Intervencionista
Coronary Artery Disease (CAD), Acute Coronary Syndrome (ACS)
Prasugrel Versus High Dose Clopidogrel in Clopidogrel Resistant Patients Post Percutaneous Coronary Intervention (PCI).
The use of dual antiplatelet therapy is considered standard of care in patients post percutaneous coronary intervention (PCI) with stenting.
- Trial name
- NCT01109784
- Testing
- prasugrel, clopidogrel
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Patras
Renal Artery Obstruction, Hypertension, Renal
The HERCULES Trial - A Safety and Effectiveness Study of the Herculink Elite Renal Stent to Treat Renal Artery Stenosis
The purpose of this study is to determine whether the Herculink Elite Renal Stent System is safe and effective in the treatment of renal artery stenosis in patients with less than optimal angioplasty results and uncontrolled…
- Trial name
- HERCULES (NCT00490841)
- Testing
- Herculink Elite Renal Stent System
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Abbott Medical Devices
Critical Limb Ischemia (CLI)
IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease
A prospective, multi-center, randomized trial to assess the safety and effectiveness of Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System (IBS Titan™) in treating patients with infrapopliteal arterial stenosis or…
- Trial name
- GENIUS (NCT04849325)
- Testing
- Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System (IBS Titan™), Percutaneous Transluminal Angioplasty (PTA) Device
- Where
- 29 sites in China
- Volunteers
- 120 people
- Sponsor
- Biotyx Medical (Shenzhen) Co., Ltd.
Femoral Artery Stenosis, Angioplasty
an Observational Study Evaluting the Effectiveness and Safety of DKutting LL Noval Scoring Balloon Angioplasty for Vessel Preparation Facilitated by IVUS on the Lower Limb Ischemia Patients With Calcified Lesions
This is a prospective, single-center, single-arm, observational study. It plans to enroll 58 patients with moderate to severely calcified lesions in the femoropopliteal or infrapopliteal arteries.
- Conditions
- Femoral Artery Stenosis, Angioplasty, Cutting Balloon Angioplasty, Calcifications, Vascular
- Trial name
- DkuLL CALVEP (NCT07397390)
- Testing
- DKutting LL scoring balloon angioplasty
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Coronary Artery Disease
Characterization of Factors Influencing the Cognitive Decline in Patients With Coronary Artery Disease
The real impact of cardiac surgery and coronary angioplasty remains to be clarified and, where appropriate, the influencing factors in a way beneficial or deleterious remain to be identified.
- Trial name
- COGCAR (NCT00946959)
- Testing
- Cardiac surgery
- Where
- France
- Volunteers
- 155 people
- Sponsor
- University Hospital, Lille
Critical Limb Ischemia, Peripheral Arterial Occlusive Disease
Cryoplasty CLIMB-registry
In 5 Belgian hospitals, the data of 100 CLI-patients receiving the cryoplasty technique to treat their infrapopliteal arterial lesions will be collected.
- Trial name
- CLIMB (NCT00459888)
- Testing
- PolarCath Peripheral Dilatation System (Boston Scientific)
- Where
- 4 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Flanders Medical Research Program