Clinical trials: Angle Closure Glaucoma
Angle-Closure Glaucoma
The Beijing Angle Closure Progression Study
The Beijing angle closure progression study (BAPS) aims to explore the 5-year incidence of PACS progressing to PAC or PACG and to determine the possible risk factors of disease progression, which may provide the evidence for…
- Trial name
- NCT05563623
- Where
- China
- Volunteers
- 825 people
- Sponsor
- Peking University People's Hospital
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary Glaucoma
With the improvement of health system, the life span of Asians has increased tremendously especially in Malaysia. As an early preparation to be an 'aging country' in 2023, Malaysia needs to prepare infrastructure and policy to…
- Trial name
- MaGESII (NCT04736264)
- Testing
- Visual rehabilitation module: navigation and mobility, Visual rehabilitation module: exercise, Visual rehabilitation module: reading
- Where
- Malaysia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Glaucoma, Angle-Closure
Comparison of Superior vs Nasal/Temporal Laser Peripheral Iridotomy in Primary Angle Closure
The purpose of this study is to determine if location of laser peripheral iridotomy (LPI) that is the standard of care treatment for angle closure glaucoma is related to changes in post-operative intraocular pressure (IOP)…
- Trial name
- NCT03187821
- Testing
- Laser peripheral iridotomy
- Volunteers
- 1,000 people
- Sponsor
- Venkatesh Rengaraj
Glaucoma, Angle-closure
Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure
This study was to evaluate the efficacy and safety of immediate anterior chamber paracentesis (ACP) with a 30-gauge needle as an initial treatment for acute primary angle closure (APAC).
- Trial name
- NCT01923454
- Testing
- Paracentesis, Acetazolamide, Peripheral iridotomy
- Where
- Thailand
- Volunteers
- 15 people
- Sponsor
- Siriraj Hospital
Glaucoma, Glaucoma Eye
MicroPulse TLT - UK Study
This Prospective Interventional Study will assess the efficacy of MPTLT in the UK.
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle, Glaucoma Secondary
- Trial name
- MPTLTUKS (NCT05593354)
- Testing
- Micropulse Transscleral laser therapy
- Volunteers
- 250 people
- Sponsor
- Imperial College Healthcare NHS Trust
Glaucoma, Glaucoma, Open-Angle
Longitudinal Study on Glaucoma Surgery Using XEN® Gel Stent
To evaluate the safety and efficacy of the XEN® Gel Stent in mild to moderate glaucoma patients undergoing glaucoma surgery.
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Angle-Closure, Glaucoma, Primary Open Angle
- Trial name
- NCT03151577
- Testing
- XEN® Gel Stent implantation
- Volunteers
- 150 people
- Sponsor
- Swiss Vision Network
Angle Closure Glaucoma, Glaucoma
Anterior Segment Changes by Optical Coherence Tomography (OCT) in Phaco- Trabeculectomy
1. Develop a measurement protocol by OCT imaging and characterization of the anterior chamber change in glaucoma patients before and after surgery. 2. Show the effect of combined surgery in control of intra ocular pressure.
- Conditions
- Angle Closure Glaucoma, Glaucoma, Cataract Secondary
- Trial name
- NCT03626675
- Testing
- phaco- trabeculectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Glaucoma
IOP Pattern in Primary Angle Closure and Primary Angle Closure Glaucoma Patients, Before and After LPI
The purpose of the study is to determine the relationship of the intraocular pressure patterns recorded during 2 sessions using Triggerfish, before and after elective laser peripheral iridotomy in angle closure glaucoma patients
- Trial name
- NCT01906151
- Testing
- SENSIMED Triggerfish®
- Where
- France
- Sponsor
- Sensimed AG
Glaucoma, Angle-Closure
Lens Extraction Combined With Goniosynechialysis Versus Trabeculectomy
To compare the effectiveness of lens extraction combined with goniosynechialysis and trabeculectomy in treating advanced angle-closure glaucoma.
- Trial name
- NCT04703712
- Testing
- Lens extraction combined with goniosynechialysis, Trabeculectomy surgery
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Primary Angle-Closure Glaucoma
Vitreous Zonule in Primary Angle-Closure Glaucoma
This study aims to investigate the role of the vitreous zonule (VZ) in the pathogenesis of primary angle-closure glaucoma (PACG) and to explore the feasibility of three-dimensional ultrasound biomicroscopy (3D-UBM) for imaging…
- Trial name
- NCT07523139
- Where
- China
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Primary Angle-Closure Glaucoma
The Multi-Omics Analysis of Lens Zonule Relaxation in The PACG Pathogenesis
Compared with primary angle-closure glaucoma (PACG) patients without zonular laxity and the control group, there are differentially expressed molecules in PACG patients with zonular laxity, and a potential mechanistic network can…
- Trial name
- NCT07539675
- Testing
- No Additional Experimental Intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhongnan Hospital
Glaucoma, Angle-Closure
Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Primary Angle Closure Glaucoma
To evaluate the clinical efficacy (intraocular pressure reduction , success rate, the number of antiglaucoma medication) and safety of ab interno trabeculectomy (AIT) with Trabectome in Chinese PACG .
- Trial name
- NCT02964676
- Testing
- ab interno trabeculectomy with Trabectome, trabeculectomy
- Volunteers
- 246 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Primary Angle Closure Glaucoma, Primary Angle Closure
Hydrus Microstent and Lens Extraction for the Treatment of Primary Angle-Closure Glaucoma
This study is a prospective evaluation of the Hydrus Microstent for the treatment of Primary Angle Closure (PAC) and Primary Angle Closure Glaucoma (PACG) with adjunctive cataract.
- Trial name
- NCT04622605
- Testing
- Trabecular bypass and Schlemm's canal stent
- Where
- Philippines
- Volunteers
- 31 people
- Sponsor
- Asian Eye Institute
Glaucoma, Angle-Closure
Anterior Segment Anatomic Parameters for Risk Profiling of Primary Angle-closure Glaucoma
The goal of this observational study is to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG).
- Trial name
- NCT06143943
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Min Ke
Glaucoma
Argon Laser Peripheral Iridoplasty for Primary Angle Closure Glaucoma
Glaucoma is the leading cause of irreversible blindness worldwide. With ageing of the population, glaucoma morbidity will rise, causing increased health care costs and economic burden for a condition in which visual loss, once…
- Trial name
- ALPI (NCT00980473)
- Testing
- Argon Laser Iridoplasty, Travatan/ Timolol/Azopt
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Singapore National Eye Centre
Angle Closure Glaucoma
Comparing Nd:YAG Laser and Sequential Double Frequency YAG-Nd:YAG Laser Iridotomy
No single type of laser or set of laser parameters is appropriate for all type of irides. Pure Nd:YAG laser iridotomy is very effective in the light color irides. It was considered as the gold standard for iridotomy.
- Trial name
- NCT02474238
- Testing
- The sequential technique, The pure Nd:YAG laser technique
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Prince of Songkla University
Glaucoma
Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery?
The investigators hypothesize that intracameral Triesence during glaucoma surgery will provide lower intraocular pressure through better control of ocular inflammation, thus leading to a more successful filtering procedure.
- Trial name
- NCT00853905
- Testing
- Triesence, balanced salt solution BSS
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Wills Eye
Glaucoma, Glaucoma, Open-Angle
Dresden Glaucoma and Treatment Study (DGTS)
To assure the quality of follow-up and treatment, data of glaucoma patients are stored and evaluated after anonymisation.
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Angle-Closure, Glaucoma, Low Tension
- Trial name
- NCT02959242
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Technische Universität Dresden
Glaucoma
ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function
The aim is to determine which approach, immediate argon laser peripheral iridoplasty or conventional systemic medical treatment efficiently breaks acute angle closure attack without consequent visual morbidities.
- Trial name
- Iridoplasty (NCT00485238)
- Testing
- Argon laser Iridoplasty, Intravenous acetazolamide
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Glaucoma
Anterior Chamber Angle Examination in Angle Closure Suspect Patients
The aim of this study is to detect PACG suspects using both AS OCT and Scheimpflug imaging.
- Trial name
- NCT05209204
- Testing
- ASOCT, Pentacam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University