Clinical trials: Animal Model
CMT, CMT (Charcot Marie Tooth Disease)
A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A)
The most common inherited neuropathy is Charcot-Marie-Tooth disease type 1A (CMT1A), caused by a duplication of the gene expressing PMP22.
- Conditions
- CMT, CMT (Charcot Marie Tooth Disease), CMT - Charcot-Marie-Tooth Disease, CMT1A
- Trial name
- CMT-MODs (NCT07476365)
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Acute Ischemic Stroke, Reperfusion Injury
Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE Study
Infarct growth (IG), Hemorrhagic Transformation (HT) and Cerebral Edema (CE) can be considered pivotal phenomena of clinical deterioration following an acute ischemic stroke.
- Conditions
- Acute Ischemic Stroke, Reperfusion Injury, Cerebral Edema, Hemorrhagic Transformation Due to Acute Stroke
- Trial name
- NIMBLE (NCT07422636)
- Where
- Italy
- Volunteers
- 213 people
- Sponsor
- University of Florence
Animal Model
Smart-gloves Hand Motion Tracking for Live Endoscopic Submucosal Dissection Training
Learning endoscopic submucosal dissection (ESD) is undertaken by experienced endoscopists in endoscopic mucosal resection and management of complications.
- Trial name
- EndoHandView (NCT06683326)
- Testing
- ROKOKO smart-glove
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Animal Model, Pediatric
The Effect Of Animal-Assisted Intervention
The aim of the study is to examine the effect of animal-assisted practice on fear in children admitted to the emergency room.
- Conditions
- Animal Model, Pediatric, Emergencies, Fear
- Trial name
- NCT05824624
- Testing
- ANIMAL-ASSISTED INTERVENTION, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Acute Ischemic Stroke, Reperfusion Injury
Acute Ischaemic STROKE: From LAboratory to the Patient's BED
Background: Recanalization strategies have radically changed the outcome in a significant part of stroke patients. The unpredictable occurrence of cerebral edema (CE) and hemorrhagic transformation (HT) are frequent events in…
- Conditions
- Acute Ischemic Stroke, Reperfusion Injury, Cerebral Edema, Hemorrhagic Transformation Due to Acute Stroke
- Trial name
- STROKELABED (NCT05725694)
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
HIV Infections
The Effectiveness of Human Antibodies in Influencing an AIDS-Like Disease in Monkeys
The purpose of this study is to see if an investigational vaccine can make antibodies (proteins found in blood) in humans that will influence the course of an AIDS-like disease in monkeys.
- Trial name
- NCT00031109
- Testing
- gp160 MN/LAI-2, Aluminum hydroxide
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Comparison of Epitheliotrophic Ability Between Human Serum and Commercialized Human Platelet- Cell and Animal Model
The Effect of Platelet Lysate on Corneal Epithelial Wound healing---the Collection of Human Serum From Volunteers
"Poor corneal epithelialization problem" can be found in a lot of ocular surface disorders, including limbal insufficiency, dry eye, chemical burn and neurotrophic disorders.
- Trial name
- NCT02720146
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
The Apparatus for Processing the Tubular Graft Modification Will be Designed and Evaluated., The On-site Capturing of the Endothelial (Progenitor) Cells by Peptide-mediated Selective Adhesion in Vitro and in Vivo Will Also be Elucidated.
Endothelialized ePTFE Graft by Nanobiotechnology
The replacement of autologous blood vessels by artificial grafts is urgently needed in clinical applications. Expanded polytetrafluoroethylene (ePTFE) grafts are the most clinically used artificial blood vessels because of its…
- Conditions
- The Apparatus for Processing the Tubular Graft Modification Will be Designed and Evaluated., The On-site Capturing of the Endothelial (Progenitor) Cells by Peptide-mediated Selective Adhesion in Vitro and in Vivo Will Also be Elucidated., The Patency Rate of ITRI-made Artificial Blood Vessels Will be Evaluated by the Porcine Animal Model.
- Trial name
- NCT02002104
- Where
- Taiwan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Schizophrenia
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia
This project entitled "A Study on Risk Mutations of the Vulnerability Genes of Schizophrenia" (RIGOS) is a continuous effort following the well founded and arduous work of genetic study on schizophrenia (SCH) by the Genomic…
- Trial name
- NCT00155207
- Where
- Taiwan
- Volunteers
- 1,065 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital