Clinical trials: Ankle
Physical Therapy
Impact of Physiotherapy Intervention for Children With Ankle Sprains
This study will investigate whether adding a physiotherapy intervention to standard Emergency Department care will lead to improved recovery following an ankle sprain in the pediatric and adolescent population as well as to a…
- Trial name
- NCT01405274
- Testing
- Physiotherapy
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Traumatic Amputation of Lower Extremity
Effects of Wearing a Powered Ankle-Foot Prosthesis on Amputee Walking
Amputees wearing a conventional prosthesis require 20-30% more metabolic energy to walk at the same speeds as non-amputees and this discrepancy is more apparent at faster walking speeds.
- Trial name
- NCT00869947
- Testing
- Powered ankle-foot prosthesis, No device
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long term effectiveness and safety of AUGMENT® Bone Graft vs. autologous bone graft.
- Trial name
- NCT02879149
- Testing
- AUGMENT® Bone Graft, Standard of Care
- Where
- 26 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- BioMimetic Therapeutics
Chronic Ankle Instability
Comparative Spectroscopic Analysis of Synovial Fluid From the Stable and Unstable Ankle
A population of patients with chronic ankle instability for whom arthroscopic ligament stabilisation was indicated. Main objective: to use the Raman microspectroscopy technique to characterise the synovial fluid of the unstable…
- Trial name
- ALSACE (NCT06228378)
- Testing
- Raman microspectroscopy
- Where
- France
- Volunteers
- 25 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Athletic Injuries, Knee Injuries
Analysis of Balance and Functional Hop Tests in Athletes With Lower Extremity Injuries by Dual Task Study
Functional Hop tests and balance measurements are frequently used to decide on returning to sports after lower extremity injuries.
- Conditions
- Athletic Injuries, Knee Injuries, Ankle Injuries, Hip Injuries
- Trial name
- NCT05484778
- Testing
- Dual tasking paradigm
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Chronic Ankle Instability
A Prediction Model for Chronic Ankle Instability
Chronic ankle instability is a common problem that may follow an ankle sprain. Until a patient has developed chronic ankle instability they are ineligible for surgical treatment although early surgical treatment yields better…
- Trial name
- Predict (NCT02955485)
- Testing
- Patients do not undergo any type of interventions, but standard care if offered and accepted.
- Where
- 4 sites in Netherlands
- Volunteers
- 460 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ankle Sprain
Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
This study will investigate the efficacy of the Indomethacin patch in pain relief of ankle sprain in adult patients, compared to a placebo patch
- Trial name
- NCT01957215
- Testing
- Indomethacin
- Where
- 15 sites in China
- Volunteers
- 270 people
- Sponsor
- GlaxoSmithKline
Osteochondral Lesion of Talus, Ankle Arthritis
Treatment Outcome After Ankle Joint Surgeries
Osteochondral lesion of talus (OLT), osteoarthrosis and impingement/instability syndrome are most common ankle joint pathologies.
- Conditions
- Osteochondral Lesion of Talus, Ankle Arthritis, Instability; Ankle (Ligaments) (Old Injury), Impingement Syndrome of Ankle
- Trial name
- NCT04132076
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Ljubljana
Foot Deformities, Acquired, Disorder of Joint of Foot
A Clinical Study of Outcomes in Foot and Ankle Bone Grafting Using map3® Cellular Allogeneic Bone Graft
This is a single arm pilot study in patients requiring surgical fusion in the foot or ankle. Patients will receive map3® Cellular Allogeneic Bone Graft containing donor matched stem cells.
- Conditions
- Foot Deformities, Acquired, Disorder of Joint of Foot, Fracture of Foot, Deformity of Bone
- Trial name
- NCT02161016
- Testing
- map3
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- RTI Surgical
Ankle Osteoarthritis
Total Ankle Replacement Using Guides, Expert Versus Trainee
Patient Specific Instrumentation (PSI) is thought to quicken joint arthroplasty surgery by shortening the operation time and improving alignment.
- Trial name
- TARGET (NCT05729958)
- Testing
- CT scan
- Volunteers
- 20 people
- Sponsor
- Centre for Orthopaedic Research Alkmaar
Postoperative Pain, Video-assisted Thoracoscopic Surgery (VATS)
Effect of Transcutaneous Electrical Nerve Stimulation Based on Wrist-ankle Acupuncture Theory on Postoperative Pain After Video-assisted Thoracoscopic Surgery
At present, surgical resection remains one of the main methods for the radical treatment of lung cancer. Compared with traditional thoracotomy, Video-assisted Thoracoscopic Surgery (VATS) offers obvious advantages, such as less…
- Trial name
- NCT06744166
- Testing
- TENS-WAA
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Changhai Hospital
Trauma
Unimalleolar Versus Bimalleolar Fixation in Bi- or Trimalleolar Ankle Fracture
A one third of all ankle fractures are bi- or trimalleolar. Traditionally these fractures are treated by both medial and lateral osteosynthesis, sometimes accompanied by osteosynthesis of the posterior malleolus.
- Trial name
- NCT01757951
- Testing
- Unimalleolar fixation, Bimalleolar fixation
- Where
- Finland
- Volunteers
- 126 people
- Sponsor
- University of Oulu
Ankle Fusion, Hindfoot Arthrodesis
Orthofix PhysioStim PEMF Ankle Fusion Retrospective
This study examines the effect of using the PhysioStim bone growth stimulator on subjects undergoing treatment for ankle and hindfoot fusion surgery.
- Conditions
- Ankle Fusion, Hindfoot Arthrodesis, Ankle Arthrodesis, Tibiotalar Arthrodesis
- Trial name
- PSAF (NCT07282067)
- Testing
- Pulsed electromagnetic field (PEMF) stimulation, Control
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- Orthofix Inc.
Chronic Ankle Instability
The Impact of Real-World Vibration Feedback Gait Retraining on Gait Biomechanics in People With Chronic Ankle Instability
People with chronic ankle instability (CAI) demonstrate altered gait or walking mechanics which cause people to walk on the outside of their foot and increases the risk of additional ankle sprains, abnormal cartilage strain, and…
- Trial name
- RWVF (NCT05327244)
- Testing
- Real-world vibration feedback gait retraining
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Sprain of Ankle
Evaluation of the Effect of the Association of Proton Pump Inhibitor (PPIs) With Non-Steriodal Anti-Inflamatories (NSAIDs) in Work Leave Time.
Retrospective cohort study to evaluate the effect of the association of PPIs with NSAIDs in work leave time.
- Trial name
- NCT00717119
- Where
- Spain
- Volunteers
- 6,356 people
- Sponsor
- AstraZeneca
Foot Drop, Peripheral Nervous System Diseases
Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot, when used during treadmill walking, in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or…
- Conditions
- Foot Drop, Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Mobility Limitation
- Trial name
- NCT03556709
- Testing
- Treadmill Ankle Robot Training
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
Cerebral Palsy, Spastic, Hemiplegic Cerebral Palsy
Changes in Muscle Activity of Children With Spastic Unilat Cerebral Palsy Using 2 Types of Ankle-foot Orthoses to Walk
The aim of this study is to investigate if ankle-foot orthoses affect changes in muscle activity of children with spastic unilateral cerebral palsy during walking.
- Trial name
- NCT03361930
- Testing
- Ankle-foot orthosis
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Stroke
Effect of Agonist Contract Relax Versus Antagonist Contract Relax in Chronic Stroke Patient.
It will be a randomized control trial with 112 patients which will be divided into two groups of 56 patients in each group. Participants will recruit through convenient sampling techniques.
- Trial name
- NCT05957731
- Testing
- Routine physical therapy, antagonist contract relax, agonist contract relax
- Where
- 2 sites in Pakistan
- Volunteers
- 112 people
- Sponsor
- University of Lahore
Ankle Sprains, Ankle Injuries
The Effect of Different Talocrural Joint Mobilization Techniques in Lateral Ankle Sprain
Decreased ankle dorsiflexion range of motion (DFROM) has been identified among the factors that increase the risk of lateral ankle sprain (LAS) in basketball players.
- Conditions
- Ankle Sprains, Ankle Injuries, Kinesiophobia, Jumping From Height
- Trial name
- NCT06295198
- Testing
- Single lep drop jump test
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bahçeşehir University
Autism
Assessment Of Spinal Posture, Balance And Ankle Muscle Shortness İn Children With Autism
The aim of this study is to evaluate spinal posture, mobility, balance and ankle muscle shortness in children with autism. The study will feature two groups, First group will consist of children with autism Second group will…
- Trial name
- NCT06995716
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
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