Clinical trials: Ankle
Lower Eyelid Retraction
Acellular Dermal Matrix vs Autologous Tarsus for Correction of Lower Eyelid Retraction
The goal of this clinical trial is to compare the effectiveness of two promising implants in treatment of lower eyelid retraction in 40 patients.
- Trial name
- NCT06926686
- Testing
- Autologous tarsus, Acellular dermal matrix
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Haukeland University Hospital
Intravenous Cannulation
AccuVein AV400 Device Versus Ultrasound-guided Cannulation of the Great Saphenous Vein at the Ankle in Infants
Establishment of venousaccess in the age group ≤12 months can be difficult and associated with repetitive punctures . Numerous techniques to facilitate peripheral venous puncture have been described such as local warming…
- Trial name
- NCT04164862
- Testing
- AccuVein AV400 Device Versus Ultrasound-guided Cannulation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Lateral Ankle Sprain
Blood Flow Restriction and Proprioception Training on Ankle Joint Sensations
Thirty-four participants with grade I and II recurrent ankle sprain, were referred from orthopaedic physician. Their ages ranged from 20 to 30 years old. All participants will be divided randomly into two groups A, B.
- Trial name
- NCT07030634
- Testing
- conventional physical therapy, Low load blood flow restriction, proprioception training
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hemophilia
Self-myofascial Release in Hemophilic Ankle Arthropathy
Introduction: Hemophilic ankle arthropathy is manifested by degenerative functional alterations (deficit of muscle strength, mobility and proprioception) (intra-articular alterations) and chronic pain.
- Trial name
- NCT05104164
- Testing
- Self-myofascial release
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Ankle Injuries, Ankle Sprains
Foam Rolling and Tissue Flossing of the Cuff Muscles
The hypothesis is that self-myofascial release (SMR) intervention on the cuff muscles would affect positively sprint performance and jump height, as well as, decrease Achilles tendon stiffness.
- Trial name
- NCT04367532
- Testing
- Foam rolling, Tissue flossing
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Avascular Necrosis of Bone, Sickle Cell Disease
Autologous Bone Marrow Stem Cell Transplantation for Osteonecrosis in Sickle Cell Disease
The purpose of this study is to evaluate the safety and efficacy of autologous bone marrow stem cells in sickle cell disease patients with osteonecrosis
- Trial name
- NCT02448121
- Testing
- Autologous bone marrow stem cell graft
- Volunteers
- 100 people
- Sponsor
- Federal University of Bahia
Cerebral Palsy
Safety and Performance of Agilik in CP
The purpose of this post market study is to demonstrate the safety and performance of a powered extension assist (EA) knee ankle foot orthosis (KAFO), or EA-KAFO, in individuals with knee extension deficiency due to cerebral…
- Trial name
- Agilik (NCT05746871)
- Testing
- Agilik, standard care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Rotator Cuff Tears, Shoulder Injuries
Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT07052721
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Diego
Ischemic Stroke
The Prevalence of a Low Ankle-Brachial Index in Acute Cerebral Ischemia.
Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the…
- Trial name
- NCT03948399
- Testing
- Duplex scanning of carotid arteries, ABI measurement
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Biziel University Hospital No 2 in Bydgoszcz
Arthrodesis, Degenerative Arthritis
INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation
The primary objective of this study is to evaluate the radiographic outcomes of Total Ankle Arthroplasty in patients having a calcaneal stem.
- Conditions
- Arthrodesis, Degenerative Arthritis, Rheumatoid Arthritis, Complications; Arthroplasty, Mechanical
- Trial name
- NCT01366989
- Testing
- Radiographic evaluation of previously implanted patients
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stryker Trauma and Extremities
Moderate-to-severely Painful Ankle Surgery
Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery
Postoperative pain remains undertreated. Opioids have well-known limitations for both individuals and society, and while single-injection peripheral nerve blocks with unencapsulated local anesthetic provide potent analgesia…
- Trial name
- NCT06995352
- Testing
- Popliteal nerve block including liposomal bupivacaine, Adductor canal nerve block including liposomal bupivacaine, Continuous popliteal nerve block with normal saline
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of California, San Diego
Rehabilitation After Ankle Injuries
The Influence of Stability Boots on Gait Pattern in Healthy Adults
After an ankle injury like distorsions, fractures or arthrodeses, or congenital defects ankle support limit the range of motion in the joint, help pain relief, control loading of the injured tissues and promote recovery of a…
- Trial name
- NCT03038815
- Testing
- VACOped, Ortho Tri
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institute for Biomechanics, ETH Zürich
Instability; Ankle (Ligaments) (Old Injury), Sprain of Ankle
A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability
The ROCKY REHAB trial will provide a pragmatic approach to evaluate if incorporating a rocky, uneven terrain treadmill into the proprioceptive rehabilitation received during physical therapy can improve outcomes and reduce…
- Trial name
- ROCKY REHAB (NCT04999904)
- Testing
- Uneven Treadmill Intervention, Standard of Care Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 312 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Ankle Osteoarthritis
Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles
The Veteran population is prone to foot and ankle maladies from common injuries such as sprains, and diseases such as ankle osteoarthritis (cartilage damage).
- Trial name
- IDCT (NCT03440008)
- Testing
- Dynamic 3D bone motion capture, wedged insole
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Ankle Osteoarthritis
A Single Intraarticular Injection of Platelet-Rich Plasma on Pain and Physical Function in Patients With Ankle OA
Platelet-rich plasma (PRP) has been reported to be an effective treatment for knee osteoarthritis (OA). The application in ankle OA has rarely been investigated.
- Trial name
- NCT04022928
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Ankle Sprains
Validation of the Identification of Functional Ankle Instability (IdFAI) in Italian
The purpose of the study is actually the translation, cultural adaptation and psychometric validation in the Italian Version of the Identification of Functional Ankle Instability (IdFAI) English Version for use in outpatient…
- Trial name
- IdFAI-I (NCT04516980)
- Testing
- Questionnaires administration
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Padova
Ankle Disease, Ankle Injuries
Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Effect of Perineural Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries, Foot Injury, Foot Diseases
- Trial name
- NCT06086418
- Testing
- 0.9 % Sodium Chloride, 0.1mg/kg Dexamethasone, 0.05mg/kg Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Ankle Fractures
Impact of Suture Technique on Wound Healing in Ankle Fracture Surgery: A Randomized Controlled Trial
Our primary aim is to compare the complication rates of patients with ankle fractures who underwent skin closure using a running subcuticular suture pattern compared to an interrupted suture pattern.
- Trial name
- NCT06496698
- Testing
- Simple Interrupted Suture, Subcuticular Suture
- Volunteers
- 80 people
- Sponsor
- University of Puerto Rico
Sprains and Strains
Ankle Manual Therapy for Ankle Sprains
The purpose of this study is to determine the effect of using ankle manual therapy procedures on clinical outcomes in individuals with post-acute ankle sprains.
- Trial name
- AMT (NCT00888498)
- Testing
- Passive Positioning, High-Velocity, Low-Amplitude Stretch, Slow, Mobilization Stretch
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- University of the Pacific
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