Clinical trials: Ankle
Ankle Dorsiflexion
Red Light Therapy: a Potential Strategy to Reduce Sports Injury Risk?
This study investigates whether near-infrared light therapy can acutely improve ankle dorsiflexion mobility and hamstring flexibility, two factors associated with sports injury risk.
- Trial name
- DIAERESIS (NCT07477678)
- Testing
- Near-infrared photobiomodulation, Cycling Warm-up
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cláudio da Silva Ferreira
Postoperative Infection, Postoperative Complications
Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Infection and wound complications are the most common complications following orthopaedic foot and ankle procedures, and the infection rate following these procedures is higher than in procedures involving other areas of the…
- Trial name
- NCT03926208
- Testing
- Soak and Scrub, Clorhexadine scrub
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Rush University Medical Center
Ankle Sprain, Ankle Instability
Auto-regulated Blood Flow Restriction in Athletes With Recurrent Ankle Sprain
Ankle injuries, especially lateral ankle sprains, are prevalent in physically active individuals. Blood Flow Restriction Training (BFRT) has emerged as a promising method, employing partial arterial occlusion and full venous…
- Trial name
- NCT06962943
- Testing
- Auto-regulated Blood Flow Restriction Training, Non-regulated Blood Flow Restriction Training, Control group
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia
The Relationship Between Lower Limb Functionality, Foot Joint Position Sensation and Balance in Haemiplegic Patients
Stroke is defined as a neurological disorder resulting from acute focal damage to the central nervous system caused by vascular factors, which may include cerebral infarction, intracerebral haemorrhage and subarachnoid…
- Conditions
- Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia, Getting 20 Points or More in the Mini Mental Test, Volunteering to Participate in the Study
- Trial name
- NCT06043960
- Testing
- Humac Norm İsokinetic Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Chronic Ankle Instability and Balance
Core Stability Traning Exercises in Chronic Ankle Instability in Atheletes
To study the effect of adding Core stability exercise to the conventional Program of Chronic ankle instability on balance, Functional instability, and Performance in athletes with CAI
- Trial name
- NCT06678503
- Testing
- balance exercise, Core stability exercises
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Ankle Foot Orthosis (AFO), Stroke Patients
AFO Prescription to Optimize Post-Stroke Function
The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis…
- Conditions
- Ankle Foot Orthosis (AFO), Stroke Patients, Post-Stroke Hemiparesis
- Trial name
- NCT06692686
- Testing
- Pre-fabricated (PF) ankle-foot orthosis (AFO), Carbon-strut (CS) ankle-foot orthosis (AFO), Multifunctional articulating (MA) ankle-foot orthosis (AFO)
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Texas at Austin
Ankle Stiffness
Effects of Dry Needling the Calf Muscles on Biomechanics and Muscle Function in Individuals With Restricted Dorsiflexion
The goal of this observational study is to learn about the acute effects of dry needling the soleus muscle in individuals with limited ankle mobility
- Trial name
- NCT07474948
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Dayton
Ankle Fractures
Postoperative Computed Tomography Detection of Syndesmotic Malreduction in Ankle Fractures
This prospective observational cohort study aims to evaluate the ability of postoperative plain radiographs to detect syndesmotic reduction accuracy in patients with ankle fractures requiring syndesmotic fixation.
- Trial name
- NCT07338149
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Postoperative Pain, Cerebral Palsy
Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy
Popliteal block is a technique for providing postoperative pain management in children. In this randomized double-blinded study, the investigators evaluated the effects of preoperative popliteal nerve block on postoperative pain…
- Trial name
- NCT02507700
- Testing
- Popliteal block, Sevoflurane, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Hypertension, Oedema
A Clinical Study Comparing Ankle Swelling Caused by Two Different Blood Pressure Medications, Levamlodipine and Amlodipine, in Post-menopausal Women With Mild High Blood Pressure.
High blood pressure is often treated with a medication called Amlodipine, but it can cause uncomfortable ankle swelling, especially in women.
- Trial name
- TERESA (NCT07618806)
- Testing
- Amlodipine
- Volunteers
- 344 people
- Sponsor
- Zentiva, k.s.
Ankle Sprains
Design and Validation of a Mobile Health Application for Home-Based Musculoskeletal Therapy in Ankle Sprain
"Ankle sprain is a common musculoskeletal injury that can pointedly influence the quality of life of an indivual. Old rehabilitation approaches often require recurrent clinic visits, which can be time-consuming, costly, and…
- Trial name
- NCT06905418
- Testing
- Clinic, Mobile App
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Superior University
Acute Ankle Sprain, Ankle Ligament Rupture
Functional Treatment for Acute Ankle Sprains: Softcast Wrap Versus MOKcast
In this study we compare two treatment options for ankle sprains. 100 patients were randomised between a flexible cast treatment and a removable and adjustable brace made out of the same materials. Follow-up was 4 months.
- Conditions
- Acute Ankle Sprain, Ankle Ligament Rupture, Ankle Injuries
- Trial name
- NCT01586390
- Testing
- Functional treatment for ankle sprain using ankle cast, Ankle sprain treated with removable ankle support
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Spaarne Gasthuis
Postoperative Pain
Effect of Dexamethasone and Epinephrine on the Duration of Sciatic Nerve Blocks With Ropivacaine
The aim of the present study is to test that adding dexamethasone or epinephrine significantly prolongs the duration of sciatic nerve blocks with ropivacaine and that the magnitude of the effect differs among dexamethasone and…
- Trial name
- NCT02104778
- Testing
- Dexamethasone, Epinephrine
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Peripheral Arterial Disease, Diabetic Foot
Implementation of ABI and WIfI in Rural Health Clinics
The objective of this project is to assess the fidelity and sustainability of in improving provider performance with Ankle Brachial Index (ABI) assessment and ulcer staging with the would ischemia foot infection (WIfI) tool for…
- Conditions
- Peripheral Arterial Disease, Diabetic Foot, Diabetes Mellitus
- Trial name
- NCT04337723
- Testing
- ABI/WIFI scoring
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of California, Davis
Cardiovascular Complications, Myocardial Infarction
Ankle-Brachial Index Estimating Cardiac Complications After Surgery
Introduction: Patients undergoing noncardiac surgery are at increased risk of cardiovascular complications. The development of methods that can accurately predict the occurrence of these events is of critical importance and large…
- Conditions
- Cardiovascular Complications, Myocardial Infarction, Acute Coronary Syndromes
- Trial name
- ABRACOS (NCT01452282)
- Where
- Brazil
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain
Brief Mindfulness for Foot and Ankle Pain
This is a single-site, four-arm, parallel-group randomized clinical trial (RCT). The clinical effects of three different formats of a very brief (i.e., 3 minute), audio-recorded mindfulness intervention for foot and ankle…
- Trial name
- NCT05939843
- Testing
- Pain Coping Information, Mindfulness Practice (alone), Mindfulness Introduction + Mindfulness Practice
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Utah
Primary Prevention
Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis
Subclinical atherosclerosis is the atherosclerotic process identified before clinical symptoms and thus it can be a useful marker of future cardiovascular events. It can be evaluated by many methods.
- Trial name
- NCT02487615
- Where
- 2 sites in Brazil
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Children, Only
Correlation Between Toilet Sitting Position, Ankle Range of Motion, and Lower Limb Strength in Children
This study investigates the relationship between different toilet sitting styles (squat vs. western) and their effects on ankle range of motion (ROM), constipation symptoms, and lower limb strength in school-going children aged…
- Trial name
- NCT07576491
- Where
- Pakistan
- Volunteers
- 191 people
- Sponsor
- Riphah International University
Bimalleolar Fractures of the Ankle., Sciatic Nerve Block.
To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Clonidine as an adjuvant to local anaesthetics prolongs the postoperative analgesia. It is predominantly an alpha 2 agonist, but does have some alpha 1 activity. Clonidine alone produces analgesia.
- Conditions
- Bimalleolar Fractures of the Ankle., Sciatic Nerve Block., Saphenous Nerve Block., Post Operative Analgesia Duration.
- Trial name
- NCT01759524
- Testing
- Bupivacaine, Lidocaine
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Adult ALL, Healthy
Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics
The proposed study evaluates the effect of medial and lateral wedges and carbon fiber custom dynamic orthoses (CDOs) on lower limb forces and motion during walking.
- Trial name
- CDOKNEEpilot (NCT05209360)
- Testing
- Medial or Lateral Wedge, Carbon Fiber Custom Dynamic Orthosis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
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