Clinical trials: Ankle Deformity
Hemophilia A
Manual Therapy in Hemophilic Arthropathy of the Ankle
Introduction: Haemophilic ankle arthropathy manifests as functional (deficit in muscle strength, mobility and proprioception), intra-articular degenerative alterations and chronic pain.
- Trial name
- NCT06816056
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Down's Syndrome
Treadmill Training With and Without Weighted Ankle Cuffs on Gait Parameters
Down syndrome is a condition in which a person has an extra chromosome. Chromosomes are small "packages" of genes in the body. Down syndrome (DS), also known as trisomy 21, is caused by the presence of all or part of a third copy…
- Trial name
- NCT06176755
- Testing
- Treadmill training with weighted ankle cuffs, Treadmill training
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hemophilia
Self-myofascial Release With Foam Roller in Patients With Hemophilic Ankle Arthropathy
Introduction: Hemophilic ankle arthropathy is manifested by degenerative functional alterations (deficit of muscle strength, mobility and proprioception) (intra-articular alterations) and chronic pain.
- Trial name
- NCT03914287
- Testing
- Self-Myofascial release
- Where
- Spain
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Foot and Ankle Surgeries, Bunion
Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Epidemiology of foot and ankle surgeries that present to the hospitals in the US are often underestimated. However there has been growing emphasis on identification of these injuries and practice patterns.
- Trial name
- NCT03653429
- Testing
- Tranexamic Acid, Normal saline
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Charcot-Marie-Tooth Disease
Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care
Here the investigators aim to show that a focused lower extremity resistance strength training program in patients with Charcot-Marie-Tooth disease (CMT) results in increased motor strength of ankle plantar- and dorsi-flexion.
- Trial name
- NCT03715283
- Testing
- Home Ankle Strengthing Program, Standard of Care
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cardiovascular Disease
Evaluation of Non-invasive Measurements of Atherosclerosis in Cardiovascular Risk Stratification
Multiple risk factors contribute to atherosclerosis, which ultimately results in clinical manifestation of cardiovascular disease.
- Trial name
- NIMA (NCT01555294)
- Where
- Netherlands
- Volunteers
- 1,960 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Haemophilia
Effectiveness of the Myofascial Therapy in the Hemophilic Arthropathy of Ankle
Randomized clinical trial to assess the efficacy of a treatment protocol applied fascial therapy in patients with hemophilic arthropathy ankle, oriented to know and describe the observed differences on the dependent variables…
- Trial name
- NCT02825667
- Testing
- Physiotherapy sessions
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Real Fundación Victoria Eugenia
Ankle Disease, Foot Deformities
Effect of Systematic Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Effect of systematic dexamethasone on the duration of popliteal nerve block after pediatric ankle/foot surgery
- Conditions
- Ankle Disease, Foot Deformities, Foot Diseases, Cerebral Palsy
- Trial name
- NCT05887765
- Testing
- Sodium Chloride 0.9% Inj, 0,1mg/kg Dexamethasone, 0,2mg/kg Dexamethasone
- Where
- 2 sites in Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Equinus Deformity
Dynamic Evaluation of Ankle Joint and Muscle Mechanics in Children With Spastic Equinus Deformity Due to Cerebral Palsy
This research will lead to the first evaluation of intrinsic and dynamic joint and muscle mechanics of equinus in cerebral palsy. It would provide a direct cause and effect relationship between equinus and bone deformity.
- Trial name
- EQUINUS (NCT02814786)
- Testing
- MRI scanner, Gait analysis
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Haemophilia
Functional and Proprioceptive Status in Patients With Hemophilic Ankle Arthropathy
Introduction: Hemophilic ankle arthropathy is manifested by functional degenerative alterations (muscle strength deficit, mobility and proprioception), intra-articular and chronic pain. Design: Case-control study.
- Trial name
- NCT05425888
- Testing
- Hemophilia group
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Dorsiflexion Deformity of Foot
Different Mobilization Techniques on Balance, Gait, Jumping and Foot Plantar Pressure
Adequate ankle dorsiflexion range of motion is important for normal performance of functional activities such as walking, running and climbing stairs.
- Trial name
- NCT05814029
- Testing
- Mobilization with movement for Ankle
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Muhammet Ayhan ORAL
Lumbar Spine Instability, Balance
Relationship Between Foot-ankle Characteristics and Lumbopelvic Control, Balance and Physical Performance
It has been shown that foot and ankle postural disorders can alter the biomechanic of lower extremity and pelvis. This situation can affects balance, postural control and phsical performance of individual adversely.
- Conditions
- Lumbar Spine Instability, Balance, Physical Performance, Foot
- Trial name
- NCT03359083
- Testing
- Correlation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Flexible Flatfoot
The Effect of Different Exercises on Lower Extremity Performance in Flexible Flatfoot
In the study, the effects of two different strengthening exercises combined with short foot exercise on lower extremity functional performance and muscle strength will be examined and compared in adults aged 18-45 years with…
- Trial name
- NCT06482580
- Testing
- PNF exercise, Clam exercise, Short-foot exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Hemophilia, Arthropathy of Knee
Evaluation of Static Postural Balance in Children With Hemophilia and Its Relationship With Joint Health
Hemophilia is a rare hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX.Bleeding disorders mainly affect the musculoskeletal system.
- Conditions
- Hemophilia, Arthropathy of Knee, Arthropathy of Ankle or Foot
- Trial name
- NCT04406519
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Exercise, Flatfoot
Short Foot Exercises With Respiratuar Exercises
Pes planus is a common foot problem since childhood, which may include loss of height of the medial longitudinal arch, which is the most important arch supporting the foot, valgus of the hindfoot, and abduction of the midfoot…
- Trial name
- NCT05128526
- Testing
- exercise, respiratory
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Haemophilia, Arthropathy
Biomechanical Determinants and Patterns Associated to the Pathophysiological Cascade of Ankle Arthropathy in Children With Haemophilia: Non-invasive In-vivo Measurement of Foot Joints in Children With Haemophilia During Gait.
Haemophilia is a rare X chromosome-linked coagulation disorder resulting from a congenital deficiency or absence of circulating factor VIII (Haemophilia A) or factor IX (Haemophilia B).As a consequence, patients with haemophilia…
- Trial name
- 3DMKFM (NCT02229331)
- Testing
- Gait analysis
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hemophilia
Manual Therapy in the Treatment of Hemophilic Arthropathy of the Ankle
Introduction: Hemophilic ankle arthropathy is manifested by degenerative functional alterations (deficit of muscle strength, mobility and proprioception), intra-articular alterations and chronic pain.
- Trial name
- NCT05549843
- Testing
- Manual therapy
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Sinus Tarsi Abnormality
AI-Based Localization and Screening of Sinus Tarsi Abnormalities on Ankle MRI
This study constructs a lightweight AI screening workflow based on sagittal fat-suppressed ankle MRI for automatic localization and normal-abnormal classification of sinus tarsi.
- Trial name
- NCT07873411
- Testing
- Standalone Radiologist Interpretation, AI-assisted Radiologist Interpretation
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Haglund Deformity
Postural Stability and Ankle Mobility in Haglund Syndrome
The purpose of the study is to find out the impact of Haglund syndrome on ankle plantarflexion and dorsiflexion ROM, dynamic postural stability and fall risk.
- Trial name
- NCT05905952
- Testing
- balance and ROM assessment
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ankle Osteoarthritis, Flat Foot or Pes Planus
Orthotic Dose Response Study
This study will investigate the effect of foot orthoses on two common conditions (ankle osteoarthritis and symptomatic adult onset flat feet) by using a custom biplane X-ray system the group has developed to very accurately and…
- Trial name
- ODRS (NCT02629731)
- Testing
- custom orthoses with varying degrees of hindfoot posting
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development