Clinical trials: Ankle Disease
Ankle Disease
Analysis of Jumping in Patients With Ankle Instability (Ankle-optogait)
The study is, in accordance with current legislation, definable as a single-center interventional study with evaluations carried out at a single timeframe.
- Trial name
- Ankle-optoga (NCT06318494)
- Testing
- jumping performance
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Ankle Brachial Index
Ankle Brachial Index Combined With Serum Uric Acid Levels Improve Prediction All Cause Mortality and Cardiovascular Mortality in the Elderly Chinese Population
Peripheral arterial disease (PAD) is a common clinical manifestation of the systemic atherosclerotic process, and the ankle brachial index (ABI) is an ideal tool to diagnose PAD.
- Trial name
- abilities (NCT03616418)
- Testing
- antiplatelet drugs;statins;antihypertensive drugs
- Volunteers
- 3,026 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Type 2 Diabetes Mellitus (DM)
Mulligan Mobilization With Movement Versus Conventional Physiotherapy on Ankle Range of Motion, Mobility, Pain, and Quality of Life in Patients With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM) is a major global health concern associated with chronic hyperglycemia, oxidative stress, and accumulation of advanced glycation end-products, which impair connective tissue function and commonly…
- Trial name
- NCT07827625
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Ibadat International University, Islamabad
Sarcopenia
Ankle Assistance and Resistance in Older Adults
The goal of this research protocol is to improve mobility in older individuals through advances in wearable assistive devices by focusing on two specific aims.
- Trial name
- NCT06284525
- Testing
- Ankle resistance and biofeedback
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Deformity, Foot
Assessment of Surgical Correction of Deformity in Diabetic Charcot Arthropathy of the Foot and Ankle
The surgical techniques described in the literature for surgical management of diabetic charcot arthropathy of the foot and ankle include simple exostectomy, open reduction and internal fixation of neuropathic fractures, external…
- Trial name
- NCT04039308
- Volunteers
- 70 people
- Sponsor
- Kerolos Maged
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Ankle Injury
Implementation of the Low Risk Ankle Rule
Ankle injuries are a very common injury in children. Each year approximately 35000 kids present to Ontario emergency departments (ED) with this problem.
- Trial name
- NCT00785876
- Testing
- LRAR Implementation
- Where
- 4 sites in Canada
- Volunteers
- 3,000 people
- Sponsor
- The Hospital for Sick Children
Genu Varum, Genu Valgum
Retrospective Evaluation of Guided Growth Plate System Plus's Safety and Clinical Performance for the Treatment of Lower Limbs Deformities.
Orthofix is conducting this retrospective Post-market clinical follow up (PMCF) study to assess the safety and clinical performance of the Guided Growth Plate System Plus (GGPSP) device, which is a new version of the Guided…
- Conditions
- Genu Varum, Genu Valgum, Joint Diseases, Knee Deformity
- Trial name
- NCT05241691
- Testing
- Guided Growth Plate System Plus
- Where
- Italy
- Volunteers
- 69 people
- Sponsor
- Orthofix s.r.l.
Obesity & Overweight, Foot and Ankle Disorders
Effects of Whole-Body Vibration With Foot Core Exercises: A Randomized Controlled Trial
This randomized, single-blind clinical trial investigates whether adding whole-body vibration (WBV) to a supervised foot core exercise program improves ankle muscle strength, balance, and proprioception in overweight and obese…
- Trial name
- FoCo-WBV (NCT07556198)
- Testing
- Supervised Foot Core Exercise Training (No Vibration), Whole-Body Vibration via DKN Technology Xg-10 Pro
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Istinye University
Peripheral Arterial Disease
Pilot Study to Determine the Optimal Technique for Measurement of Ankle Blood Pressures
Peripheral arterial disease (PAD) is a highly prevalent medical condition. Patients with PAD are usually diagnosed on the basis of the ankle-brachial index.
- Trial name
- NCT00819598
- Testing
- BLOOD PRESSURE MEASURMENT, BLOOD PRESSURE MEASUREMENT
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Summit Doppler Systems, Inc.
Ankle Inversion Sprain, Instability, Joint
The Effect of Balance Training on Neuromuscular Control in Subjects With CAI
The goal of this study is evaluate the effect of uni-axial versus multidirectional balance training on muscle reaction time in subjects with chronic ankle instability.
- Conditions
- Ankle Inversion Sprain, Instability, Joint, Treatment, Neuromuscular Control
- Trial name
- NCT03439930
- Testing
- Balance training
- Volunteers
- 60 people
- Sponsor
- University Ghent
Cardiovascular Disease
Evaluation of Non-invasive Measurements of Atherosclerosis in Cardiovascular Risk Stratification
Multiple risk factors contribute to atherosclerosis, which ultimately results in clinical manifestation of cardiovascular disease.
- Trial name
- NIMA (NCT01555294)
- Where
- Netherlands
- Volunteers
- 1,960 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Foot and Ankle Arthrodesis, Foot and Ankle Osteotomy
Foot and Ankle Arthrodesis or Osteotomy With Io-Fix Type Fixation
The recovery of foot and ankle arthrodesis and osteotomy is still plagued by the problem of delayed consolidation or even pseudo-arthrosis.
- Trial name
- NCT04812353
- Testing
- Follow-up of Io-Fix type fixation
- Where
- Belgium
- Volunteers
- 208 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
End-stage Ankle Arthritis (ESAA), Osteoarthritis (OA)
Comparing Ankle Fusion to Ankle Replacement
End-stage ankle arthritis (ESAA) is a debilitating condition associated with severe pain, dysfunction, and reduced quality of life.
- Trial name
- NCT01620541
- Testing
- Ankle Arthrodesis, Ankle Arthroplasty
- Where
- 6 sites in United States
- Volunteers
- 517 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Bunion of Unspecified Foot, Bunionette of Unspecified Foot
Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study
Orthopedic surgeons frequently prescribe and over-prescribe narcotic pain medications during the postoperative period, despite the ongoing opioid crisis in the United States.
- Conditions
- Bunion of Unspecified Foot, Bunionette of Unspecified Foot, Hammertoe, Ankle Fractures
- Trial name
- NCT04771741
- Testing
- Acetominophen, Toradol, Meloxicam
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Prisma Health-Midlands
Total Knee Replacement, Knee Osteoarthritis
Circulatory Exercise After Total Knee Replacement
Total knee replacement is commonly associated with early postoperative inflammation, edema, pain, and reduced mobility. This randomized controlled trial will evaluate whether adding a simple circulatory exercise program to…
- Conditions
- Total Knee Replacement, Knee Osteoarthritis, Postoperative Edema, Postoperative Inflammation
- Trial name
- NCT07688642
- Testing
- standard postoperative TKR rehabilitation, Standard Rehabilitation Plus Circulatory Exercise
- Volunteers
- 68 people
- Sponsor
- Assiut University
Arthritis, Rheumatoid Arthritis
Wright Foot & Ankle Post-Market Observational Study
WRIGHT FOOT \& ANKLE POST-MARKET OBSERVATIONAL STUDY, Multi-Year, Multi-Site, Multi-Device, Post-Market Observational Study, 10 sites, a minimum of 40 patients per device
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury
- Trial name
- NCT04118894
- Testing
- Foot and Ankle Devices
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Stroke
Effect of Intermittent Pneumatic Compression on Ankle Joint Proprioception and Balance in Patients With Stroke
This study aims to assess the effect of intermittent pneumatic compression on ankle joint proprioception and balance in patients with stroke.
- Trial name
- NCT07404631
- Testing
- Intermitted pneumatic pressure, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Cairo University
Ankle Injuries, Foot Injuries
Ankle Trauma: an Emergency Nurse Assessment Study
The ankle and/or foot injuries incidence is high. Lateral ankle sprains are most common diagnosis, while fractures represent less than 15% of final diagnosis.
- Conditions
- Ankle Injuries, Foot Injuries, Diagnosis, Treatment
- Trial name
- ATENA (NCT04126837)
- Testing
- Diagnosis and treatment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Grenoble
Cardiovascular Disease, Diabetes Mellitus Type 2, Peripheral Vascular Disorder Due to Diabetes Mellitus
Weight Off-loading Training, Cardiovascular Indices, Diabetes
Aims: To evaluate the effectiveness of partial weight-bearing during aerobic exercise training on cardiovascular disease risk and peripheral vascular function in patients with type 2 diabetes mellitus.
- Trial name
- NCT06974422
- Testing
- Partial weight bearing during aerobic exercise training, Full weight bearing during aerobic exercise training, Regular oral anti-diabetic medications.
- Where
- Saudi Arabia
- Volunteers
- 46 people
- Sponsor
- Umm Al-Qura University