Clinical trials: Anorexia
Anorexia Nervosa
Remission Factors in Anorexia Nervosa
Anorexia Nervosa (AN) is a complex and multifactorial psychiatric disease that affects mostly women and is characterized by a self-restriction of food intake leading to life-threatening consequences whose underlying mechanisms…
- Trial name
- REMANO (NCT04560517)
- Where
- France
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Ventricular Septal Defect, Appetite Loss
The Effect of Transcatheter VSD Closure on Children's Appetite, Hormones and Growth
In this study; Changes in appetite, hormones and growth of ventricular septal defect patients treated with non-surgical method were evaluated.
- Conditions
- Ventricular Septal Defect, Appetite Loss, Growth Delay
- Trial name
- NCT05200910
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Healthy
Degradation of the Anorexic Hormone Peptide YY
Peptide YY (PYY) is a gastrointestinal hormone released from the enteroendocrine cell upon food intake. The N-terminal truncated form, PYY3-36, exerts anorexic effects.
- Trial name
- NCT02493959
- Testing
- PYY1-36 infusion, PYY1-36 + sitagliptin, PYY3-36 infusion
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Aging, Appetite Loss
Effect of a Novel Protein Supplement on Appetite in Older Adults
An acute randomized crossover trial comparing the effects of the whey hydrolysate, whey protein concentrate and placebo (still flavored water) on appetite and energy intake in older adults.
- Trial name
- NCT05871060
- Testing
- Whey Protein Concentrate, Whey hydrolysate
- Where
- Ireland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Anorexia Nervosa
Metabolic Phenotyping in Anorexia Nervosa
After discharge from inpatient treatment, 30-50% of patients with Anorexia Nervosa require re-hospitalization within 4-12 months.
- Trial name
- NCT02087280
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Anorexia Nervosa
A fMRI Pilot Study of the Effects of Meal-support in Eating Disorders.
This study involves people with eating disorders and healthy volunteers (people who have never experienced an eating disorder). Participants are interviewed about their psychological and physical health by the experimenter and…
- Trial name
- ET4AN (NCT02551445)
- Testing
- Gradual exposure to food stimuli
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- King's College London
Eating Disorders
Characteristics and Importance of Physical Activity in Women With Anorexia Nervosa
This study will determine the importance and the level of physical activity among women with anorexia nervosa, both during inpatient treatment and 1 year after hospital discharge.
- Trial name
- NCT00917423
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Anorexia Nervosa
Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA)
The current etiological pathological model of anorexia nervosa is poly-factorial involving individual genetic and psychological factors, in close interaction with environmental, family and socio-cultural factors.
- Trial name
- CoCA (NCT02381639)
- Testing
- One interview of 90 minutes with a part of cognitive assessment and a part of self-assessment
- Where
- France
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Anorexia Nervosa
Appetitive Conditioning in Anorexia Nervosa
Anorexia nervosa (AN) is characterized by a reduced drive to pursue rewarding experiences and stimuli. Food consumption - which is almost universally experienced as pleasurable - is not described as rewarding by those with AN.
- Trial name
- ACAN (NCT05531604)
- Testing
- appetitive conditioning
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Anorexia, Generalized Anxiety
Overgeneralization of Conditioned Fear as a Pathogenic Marker of Anorexia Nervosa
Anorexia nervosa is a chronic mental health condition characterized by maladaptive food consumption (i.e., hypophagia) and distorted body image.
- Trial name
- NCT02148042
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anorexia Nervosa
Gastrointestinal Interoception in Anorexia Nervosa
Anorexia nervosa (AN) has among the highest mortality rate of any psychiatric illness, yet we have a poor understanding of the biological causes of this disorder.
- Trial name
- NCT05111977
- Testing
- Vibrant capsule
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa, Bulimia Nervosa
Eating Disorders Genetics Initiative 2
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Avoidant Restrictive Food Intake Disorder
- Trial name
- EDGI2 (NCT06594913)
- Testing
- Eating disorder diagnosis group
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anorexia Nervosa, Adipokines
Adipokines and Ghrelin Concentrations in Different Stages of Anorexia Nervosa
The aim of this study is to determine serum concentrations of adiponectin (ApN), leptin and ghrelin in different stages of anorectic patients and to evaluate their relationships between biochemical, hormonal and anthropometric…
- Trial name
- NCT00602264
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Anorexia Nervosa
TMS and Body Image Treatment for Anorexia Nervosa
To evaluate if TMS together with a body image intervention is an efficacious treatment for anorexia nervosa compared to treatment as usual.
- Trial name
- NCT04213820
- Testing
- Transcranial magnetic stimulation, Body Image Intervention, Treatment as usual
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
Anorexia Nervosa, Stress
Cortisol, Hippocampus, and Insula in Anorexia Nervosa.
EXCENTRICC is a platform for scientific collaboration between different disciplines, all working on a common theme: adrenocortical hormones.
- Trial name
- EXCENTRICCAN (NCT05931549)
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cachexia, Anorexia
Pharmacokinetics of Megace F and Megace OS Under Fasting and Fed Conditions in Healthy Male Volunteers
Phase I study of Megace F will be conducted to investigate pharmacokinetics and safety compared to Megace OS. Phase I study divided into 3 parts written as belows.
- Trial name
- MGF (NCT01397214)
- Testing
- Megace F, Megace OS
- Where
- South Korea
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Obesity
Safety and Efficacy of APD356 in the Treatment of Obesity
This is a research study of an investigational drug, APD356, a novel, selective 5-HT2c receptor agonist, in clinical development as a potential treatment for obesity.
- Trial name
- NCT00116740
- Testing
- APD356
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Eating Disorders
Exploration by UHF MRI of Hypothalamic Networks Associated to Feeding in Obesity and Anorexia
Food intake is a motivated behaviour that consists of seeking, selecting and ingesting nutritional resources from the environment.
- Trial name
- HYPOTHALNET (NCT04451759)
- Testing
- MRI exploration
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Anorexia Nervosa
Serotonin Role on Brain Circuits Involved in Food Avoidance in Anorexia Nervosa
Serotoninergic activity in brain structures involved in food control and avoidance, such as the basal ganglia, is poorly understood in Anorexia Nervosa.
- Trial name
- SEVIALANO (NCT05155280)
- Testing
- PET imaging using [11C]DASB radioligand., Eye Tracker
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anorexia Nervosa, Metabolic Syndrome
Does Metabolic Syndrome Exist in Anorexia Nervosa?
The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of…
- Trial name
- NCT00271921
- Testing
- Calorie controlled diet
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)