Clinical trials: Anorexia
Anorexia Nervosa
Abnormal Regulation, Estimation and Cognitive Impacts of Physical Efforts as an Endophenotype of Anorexia Nervosa
The purpose of this study is to check if patients, but also relatives (as they share familial and genetic risk factors), are having more difficulties in regulating a spontaneous, pleasant physical effort (doing "too much")…
- Trial name
- CAPANOX (NCT02995226)
- Testing
- Clinical and biological examination, Saliva (or blood) test Glycemia, thermal test, cognitive and bike tests, questionnaires, Clinical examination, Glycemia, saliva (or blood) test, thermal test, cognitive and bike tests, questionnaires
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Anorexia Nervosa
Auditory Sensory Attenuation in Anorexia Nervosa
The goal of this observational cross-sectional study is to test the sensory attenuation effect with auditory stimuli comparing women affected by anorexia nervosa and healthy-weight women.
- Trial name
- UdSA_AN (NCT06298526)
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Anorexia Nervosa, Microbiome Dysbiosis
Feasibility Study of Using Fecal Microbiota Transplants in Anorexia Nervosa
The investigators hypothesize that prolonged undernutrition in anorexia nervosa alters the microbiome to a different steady-state (dysbiotic) composition that sustains the disease, even after returning to normal diet.
- Trial name
- ReBoot (NCT05834010)
- Testing
- Fecal Microbiome Transplant
- Where
- 3 sites in Denmark
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Anorexia Nervosa
Care in Patients Hospitalized for Anorexia Nervosa at the Time of the Coronavirus-19 Epidemic (QUALICOVID)
Anorexia nervosa is a severe psychiatric condition. On the nutritional level, one of the objectives recommended by the High Authority of Health is to "achieve and maintain an appropriate weight and nutritional status".
- Trial name
- QUALICOVID (NCT04387708)
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Anorexia Nervosa
Assessment of the Impact of Early Treatment for Anorexia Nervosa in a Day Hospital on Food Symptomatology, the Outcome of Young Patients, and the Family Experience
During the management of chronic illnesses, the day hospital (DH) serves as a brief and effective alternative to traditional hospitalization, offering access to multidisciplinary care.
- Trial name
- EVA-FAM (NCT06218472)
- Testing
- Day Hospital Treatment, Multidisciplinary follow-up "as usual" within the service, Conduct semi-structured qualitative interviews
- Where
- France
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anorexia Nervosa
Orexin Gene in Anorexia Nervosa
The objectives of this study will be to determine the methylation of the promoter of the Orexin A (OX-A) and B (OX-B) genes in young women (> 18 years) with Anorexia Nervosa (AN), compared with a control group; and to evaluate…
- Trial name
- ORESSANNE (NCT06800898)
- Testing
- Blood samples and Questionnaires
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Eating Disorders
Exploration by UHF MRI of Hypothalamic Networks Associated to Feeding in Obesity and Anorexia
Food intake is a motivated behaviour that consists of seeking, selecting and ingesting nutritional resources from the environment.
- Trial name
- HYPOTHALNET (NCT04451759)
- Testing
- MRI exploration
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Anorexia Nervosa
Effects of Anorexia Nervosa on Bone Mass in Adolescents
This study is to determine the effects of anorexia nervosa on bone mass and hormone levels in adolescents. Whether administration of estrogen, a normal hormone present during puberty, can help maintain bone development in girls…
- Trial name
- NCT00088153
- Testing
- Physiologic Estrogen/progesterone
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cancer Cachexia
Nutrition Education and Quality of Life in Cancer Cachexia
With the project the investigators propose, the investigators aim to find answers to the following questions: Are some cachectic factors and cytokines associated with plasma level irisin in patients with advanced stage cancer…
- Trial name
- NCT05262192
- Testing
- nutrition education
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ordu University
Undernourished, Anorexia Nervosa
Intestinal Metagenome of Undernourished in Patients
The objective of this trial is to evaluate gut microbiota changes in undernourished patients with anorexia nervosa under enteral nutrition.
- Trial name
- INT-METAVOSA (NCT02920073)
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anorexia Nervosa
Serotonin Role on Brain Circuits Involved in Food Avoidance in Anorexia Nervosa
Serotoninergic activity in brain structures involved in food control and avoidance, such as the basal ganglia, is poorly understood in Anorexia Nervosa.
- Trial name
- SEVIALANO (NCT05155280)
- Testing
- PET imaging using [11C]DASB radioligand., Eye Tracker
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anorexia Nervosa
Ketogenic Diet and Brain Response in Anorexia Nervosa
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed.
- Trial name
- NCT06540703
- Testing
- Therapeutic Ketogenic Diet (TKD)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Periodontal Diseases, Eating Disorder
Periodontal Impact of Eating Disorders (the PERIOED Study)
This study evaluated the periodontal status of patients suffering from eating disorders (anorexia nervosa and bulimia nervosa). The work hypothesis is that eating disorder patients have a higher risk for periodontal diseases than…
- Conditions
- Periodontal Diseases, Eating Disorder, Anorexia Nervosa, Bulimia Nervosa
- Trial name
- PERIOED (NCT02960152)
- Testing
- diagnostic
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot
Obesity
Safety & Tolerability of a Combination of Antidepressant and Peptic Ulcer Drug in Overweight Healthy Subjects
The hypothesis of this study is that up to 150 mg of sertraline and up to 3 mg of telenzepine will be safe, tolerable, and have the effect of suppressing appetite, when taken in combination daily by mouth by healthy, overweight…
- Trial name
- NCT01155531
- Testing
- Sertraline plus Telenzepine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Theracos
Anorexia Nervosa
Study of Food Aversion in Patients With Anorexia Nervosa
This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls.
- Trial name
- NCT03100656
- Testing
- A breakfast sandwich
- Where
- 2 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa, Eating Disorders
Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders
This randomized, controlled effectiveness trial will assess outcomes, implementation, and mechanisms of two psychological treatments for adolescent anorexia nervosa (AN) delivered in the home setting, in the context of…
- Trial name
- NCT05184556
- Testing
- Family-based treatment (FBT), Integrative family therapy
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anorexia Nervosa
Metabolic Diet for Relapse Prevention in Anorexia Nervosa
This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored…
- Trial name
- NCT05197309
- Testing
- Metabolic Diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Appetite Depressant, Overweight
Safety, Tolerability, Kinetics and Efficacy Study of Hoodia Gordonii Purified Extract (PYM50717)
The objective of this clinical study was to assess the safety, tolerability, efficacy (effects on appetite scores, food intake) and plasma kinetics of Hoodia gordonii purified extract (H.g.PE), when consumed twice-daily for 2 or…
- Conditions
- Appetite Depressant, Overweight, Body Weight
- Trial name
- NCT01306422
- Testing
- Hoodia gordonii purified extract (H.g.PE)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Eating Disorders
STERK - Strength Training and Eating Disorders
Strength training has been found effective for enhancement of bone health, muscle strength and body composition among premenopausal women from the general population, however it is unclear to what extend strength training might…
- Trial name
- NCT02142439
- Testing
- Strength training
- Where
- 3 sites in Norway
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of South-Eastern Norway
Anorexia Nervosa
The Embodied Cognition: Exploratory Study of Automatic and Controlled Processes in Anorexia Nervosa.
Anorexia nervosa (AN) is a common psychiatric illness, with severe prognosis (5% mortality) that has changed little over in half a century. One of the forms is the restrictive anorexia nervosa (ANR).
- Trial name
- NCT02538796
- Testing
- TEA + Grober Test + Task 1 + Grober Test, TEA + Grober Test + Task 2 + Grober Test, TEA + Grober Test + Implicit Task 3 + Grober Test
- Where
- France
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne