Clinical trials: Anterior Cruciate Ligament (ACL)
Anterior Cruciate Ligament Injuries
Anterior Tibial Subluxation in the Setting of ACL-injury and After ACL Reconstruction
To identify the related factors for anterior tibial subluxation (ATS) on anterior cruciate ligament-injured MRI images.
- Trial name
- NCT04956536
- Testing
- Demographic data and MRI images were extracted and analyzed
- Where
- China
- Volunteers
- 297 people
- Sponsor
- Peking University Third Hospital
Knee Ligament Injury
TEL and Clam Shell Exercises Affect After ACL
The purpose of this study to determine the effects of the addition of isolated hip strengthening exercises to traditional rehabilitation after Anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT05856071
- Testing
- goniometer, clamshells exercises, traditional physical therapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University
ACL Tears
The Effect of Tranexamic Acid Vs Torniquet on Visual Clarity in Knee Arthroscopic ACL Reconstruction
Study Objective: The study aims to determine if tranexamic acid (TXA) is as effective as a tourniquet in improving visual clarity during arthroscopic ACL reconstruction surgery.
- Trial name
- NCT06781021
- Testing
- Tourniquet, TXA
- Where
- Jamaica
- Volunteers
- 60 people
- Sponsor
- The University of The West Indies
Knee Injuries
Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing fibular collateral ligament (FCL) reconstruction alone or combined FCL and anterior cruciate ligament (ACL) reconstructions…
- Trial name
- NCT05073263
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
ACL
Interventions to Enhance Quadriceps Output After ACLR
The investigators are interested in determining what treatments are effective in reducing inhibition after anterior cruciate ligament (ACL) surgery and helping people increase quadriceps strength.
- Trial name
- NCT07674784
- Testing
- NMES, Vibration
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Wisconsin, Madison
Anterior Cruciate Ligament
Robot-Assisted Versus Conventional Arthroscopic ACL Reconstruction: A Prospective Comparative Study
This study aims to evaluate the clinical efficacy and biomechanical accuracy of a newly developed robot-assisted system for anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT07086417
- Testing
- Robot-Assisted Arthroscopic ACL Reconstruction, Conventional Arthroscopic ACL Reconstruction
- Volunteers
- 120 people
- Sponsor
- Chunyan Jiang
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Hamstring Versus Quadriceps
The use of hamstrings and quadriceps autografts as an alternative option for reconstruction of the anterior cruciate ligament has good clinical results: however, both techniques have not been compared among them, which is why…
- Trial name
- NCT04137250
- Testing
- Hamstring, Quadriceps tendon
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Anterior Cruciate Ligament Injuries
Clinical and Radiological Evaluation of ACL Reconstruction Results
The study is intended to include all patients who will undergo surgical reconstruction of the anterior cruciate ligament (ACL). The patients will be monitored and evaluated preoperatively and also at 6 months and 1 years after…
- Trial name
- NCT05504018
- Testing
- ACL reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Samsun University
Anterior Cruciate Ligament
The Long-term Degradation Outcome of Bilok Screws Used for ACL Reconstruction
The purpose of the study is to evaluate the long term outcome of a poly L-lactic acid / β-tricalcium phosphate (BILOK) biodegradable interference fixation screw used for arthroscopic bone-patellar tendon-bone ACL…
- Trial name
- NCT00374491
- Sponsor
- ArthroCare Corporation
ACL, Anterior Cruciate Ligament
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
The goal of this study is to gather pilot data to help inform a future clinical trial. As such, the investigators will employ a randomized clinical trial design, but data will only be collected on 9 total subjects.
- Conditions
- ACL, Anterior Cruciate Ligament, ACL Injury
- Trial name
- Mi-SPA (NCT06529692)
- Testing
- Split-Belt Training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Michigan
Anterior Cruciate Ligament Reconstruction
Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction
Scientific Research Question Overall Purpose: Regarding rehabilitation after anterior cruciate ligament reconstruction (ACLR), there is a knowledge gap - a lack of evidence.
- Trial name
- NCT06318039
- Testing
- Novel program, Traditional program
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Linnaeus University
ACL Injury
MRI Morphology of Femoral Notch in ACL Injury
This study aims to investigate the association between femoral notch morphology, as assessed by MRI, and the risk of ACL injury
- Trial name
- NCT06707285
- Testing
- MRI
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anterior Cruciate Ligament Rupture
Anatomic and Biomechanical Investigation on ACL: A Cadaveric Study
The present study was aimed to investigate the kinematics differences between round-tunnel (ROT) and flat-tunnel (FLT) techniques and compare the influence to the anterior root of lateral meniscus (ARLM ) in anterior cruciate…
- Trial name
- NCT04957797
- Testing
- round tunnel, flat tunnel
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Initial Graft Tension and ACL Surgery
The anterior cruciate ligament (ACL) is one of four strong ligaments connecting the bones of the knee joint. If overstretched, the ACL can tear. Reconstruction of a torn ACL is now a common surgical procedure.
- Trial name
- NCT00434837
- Testing
- Initial graft tension during ACL reconstruction surgery
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Rupture of Anterior Cruciate Ligament
Arthroscopic Primary Repair of the Anterior Cruciate Ligament (ACL)
A prospective cohort study that will be conducted at Sultan Qaboos University Hospital. It aims to determine the outcomes, in terms of, activity level, functional level, subjective knee function, range of motion, stability, and…
- Trial name
- NCT03510845
- Testing
- Arthroscopic ACL Primary Repair, Arthroscopic ACL Reconstruction
- Where
- Oman
- Volunteers
- 45 people
- Sponsor
- Sultan Qaboos University
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
Anterior Cruciate Ligament (ACL), Postural Stability
Postural Stability Following Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injuries are among the most frequent knee injuries, often leading to deficits in postural stability and balance as a result of mechanoreceptor damage, which disrupts proprioceptive feedback and…
- Trial name
- NCT07210853
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
ACL - Anterior Cruciate Ligament Deficiency, Varus Deformity of Tibia (Disorder)
Patients With Acl Injury and Varus Knee Will Undergo Acl Reconstruction Alone, or Combined With High Tibial Osteotomy in the Same Session.
The purpose of this study is to compare the results of single-stage anterior cruciate ligament reconstruction combined with high tibial osteotomy and anterior cruciate ligament reconstruction alone in knees with varus…
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, Varus Deformity of Tibia (Disorder), ACL Injury, Knee Deformity
- Trial name
- NCT05817084
- Testing
- medial opening wedge high tibial osteotomy, anterior cruciate ligament reconstruction
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mostafa Hassanein, Msc