Clinical trials: Anterior Cruciate Ligament (ACL) Reconstruction
ACL Reconstruction, Cognitive Function
Test of Return to Sport After ACL Reconstruction and Cognitive Task.
After reconstruction of the anterior cruciate ligament, the aim for the vast majority of sportspeople is to return to the field.
- Conditions
- ACL Reconstruction, Cognitive Function, Single Leg Hop Firm Surface, Testing Effect of Intervention
- Trial name
- AQQSHTATC (NCT06768957)
- Testing
- Single leg hop for distance, Single leg hop for distance plus cognitive task
- Where
- 4 sites in France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Simon VALOT
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Muscle Weakness After Anterior Cruciate Ligament Reconstruction
Contralateral Strength-training After Anterior Cruciate Ligament (ACL) Reconstruction
The main aims of the study are (1) to examine the impact of contralateral strength training on the quadriceps muscle function after ACL surgery and (2) to compare the magnitude of cross-education induced by NMES versus eccentric…
- Trial name
- NCT01901965
- Testing
- Neuromuscular electrical stimulation, eccentric training
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Anterior Cruciate Ligament Injuries
Ultrasound Evaluation of Hamstring Tendon Regeneration After ACL Reconstruction and Its Influence
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04961736
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sports Injury, Anterior Cruciate Ligament Rupture
Comparison of Functional Outcome Between BQT and SBHT ACL Reconstruction
ACL rupture has a high morbidity in productive-age population. The increasing incidence and proper management has become a point of interest in the musculoskeletal sport injury.
- Trial name
- BQTSBHTFMUI (NCT04536246)
- Testing
- Bone Quadriceps Tendon (BQT) arthroscopic-assisted ACL reconstruction, Single-Bundle Hamstring Tendon (SBHT) arthroscopic-assisted ACL reconstruction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anterior Cruciate Ligament Rupture
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
- Trial name
- NCT06294314
- Testing
- Fertilized ACL
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marshall University
ACL
LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study
The Anterior Cruciate Ligament (ACL) is a major stabiliser of the knee. ACL rupture is being increasingly identified in children and skeletally immature patients.
- Trial name
- LivD_ACLR (NCT05395767)
- Testing
- Endoscopic Anterior Cruciate Ligament reconstruction using living donor hamstring allograft from a parent donor
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maidstone & Tunbridge Wells NHS Trust
ACL Reconstruction
Application of Multiple Vertical Jump Tests in Return-to-Play Assessment for Anterior Cruciate Ligament Reconstruction Athletes
Anterior cruciate ligament (ACL) injury is a common sports-related injury, particularly in sports that require extensive jumping and cutting movements.
- Trial name
- RTP-VJ (NCT07297511)
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
ACL - Anterior Cruciate Ligament Rupture
BioACL Reconstruction With Amnion Collagen Matrix Wrap and Stem Cells Case Series
The objective of this study is to evaluate the use of wrapping an ACL graft with a collagen matrix tissue wrap and injecting autologous bone marrow aspirate concentrate under the wrapping and into the graft.
- Trial name
- BioACL(CS) (NCT03294720)
- Testing
- Bio-ACL, amnion wrap and BMAC
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Knee Ligament Injury, Anterior Cruciate Ligament Injuries
Functional Outcomes of a Criterion-based Rehabilitation Protocol for ACL Reconstruction in Amateur Athlete
Although current rehabilitation protocols following anterior cruciate ligament reconstruction (ACLR) are based on the graft remodeling process, there is uncertainty about its time schedule.
- Trial name
- NCT05719974
- Testing
- rehabilitation protocol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Anterior Cruciate Ligament (ACL) Reconstruction
Gabapentin Premedication for ACL Reconstruction: RCT
This double blind randomized control trial will enroll 100 participants ages 12-18 years, undergoing ACL repair. Participants receive gabapentin or placebo preoperatively.
- Trial name
- NCT03417479
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Patellofemoral Pain Syndrome, ACL Tear
Kinematic Assessment of Human Peripheral Joints by Dynamic CT
Aim of the research project: The entire research project aims to investigate human peripheral joints (knee, foot \& ankle, elbow, wrist \& hand) by dynamic 4D radiographic imaging acquisition during real-time motion.
- Trial name
- Karma-4D (NCT04732585)
- Testing
- Physiotherapy or Surgery
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pain, Postoperative, ACL
Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction
Liposomal bupivacaine injectable suspension (Exparel), manufactured by Pacira Pharmaceuticals, is an FDA-approved, long-lasting nonopioid analgesic that is indicated for single-dose infiltration in adults to produce postsurgical…
- Trial name
- NCT05161221
- Testing
- OxyCODONE 5 mg Oral Tablet, Naproxen 500 Mg, Tylenol Pill
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Anterior Cruciate Ligament Injury, Knee Injuries
Bone Tunnel Widening Following ACL Reconstruction
Hypothesis 1: There is less tunnel-widening with bone-patella tendon-bone graft compared with the hamstring graft when the same fixation method is used.
- Trial name
- NCT00198042
- Testing
- Surgical reconstruction of the ACL
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Reconstruction
Pediatric ACL: Understanding Treatment Options
Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four…
- Trial name
- PLUTO (NCT02772770)
- Testing
- Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions, Surgical technique: Transphyseal reconstruction, Surgical technique: Partial transphyseal reconstruction
- Where
- 10 sites in United States
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ACL Tear, ACL - Anterior Cruciate Ligament Deficiency
Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and After Anterior Cruciate Ligament Reconstruction
This prospectively study aims to evaluate the evolution of knee joint proprioception on isokinetic dynamometer before and after Anterior Cruciate Ligament (ACL) reconstruction and its relationships with muscle strength, self…
- Trial name
- PRO-ACL (NCT04058574)
- Testing
- Proprioception measurement on isokinetic dynamometer
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
ACL Injury, ACL Reconstruction
Ultrasonic Backscatter Imaging for ACL Reconstruction and Shoulder Diseases
This study explores ultrasonic scattering imaging technology in patients undergoing anterior cruciate ligament (ACL) reconstruction and those with shoulder musculoskeletal disorders.
- Trial name
- NCT06361082
- Testing
- ACL reconstruction
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University