Clinical trials: Anterior Segment of Eye
Aphakia
Intraocular Position of Secondary Iris-Fixated IOLs in Aphakic Eyes
The purpose of this study is to evaluate the intraocular stability and safety of secondary iris-fixated IOLs in aphakic patients.
- Trial name
- NCT00773266
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Glaucoma, Cataract
Comparative Study of the Cornea/Anterior Segment OCT CASIA2 and the RTVue XR OCT Avanti With AngioVue Software
This study is a prospective comparative, randomized, single center study to gather agreement and precision data in all subjects.
- Trial name
- NCT04486976
- Testing
- Cornea/Anterior Segment OCT CASIA2, Optovue RTVue XR Avanti
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Cataract Extraction
Comparison of Acular LS With Lotemax to Prevent Inflammation After Cataract Surgery and Intraocular Lens Implantation
The purpose of this study is to compare the effectiveness of Acular LS® and Lotemax® in the prevention of inflammation in the eye after cataract surgery. Acular LS is made by Allergan, Inc.
- Trial name
- NCT00366691
- Testing
- Acular LS, Lotemax
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Angle Closure Glaucoma, Glaucoma
Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies
Purpose: To evaluate short-term angle opening after argon peripheral iridoplasty using AS-OCT and to report its complications at 1-week and 1-month follow up in patients that did not achieve a satisfactory clinical angle opening…
- Trial name
- ALPIECA (NCT02199158)
- Testing
- Argon Laser Peripheral Iridoplasty
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Keratoconus
Assessment of Corneal Stiffness in Keratoconus After Crosslinking by Corvis ST and OCT.
Objectives: Measurement of corneal stiffness parameters { Deformation Amlitude (DAR1), Integrated radius, Stress parameter (SP A1), Stress strain index (SSI) and Corvis biomechanical index (CBI) } in keratoconic corneas before…
- Trial name
- NCT05161052
- Testing
- Corvis ST (dynamic Scheimpflug technology)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cairo University
Punctal Stenosis
Diagnosis of Acquired Punctal Stenosis Using Anterior Segment Optical Coherence Tomography
Purpose of the study To evaluate the lower puntum dimensions in cases of acquired punctal stenosis(APS), using anterior segment optical coherence tomography (AS-OCT).
- Trial name
- NCT03498144
- Testing
- Anterior segment OCT
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Thyroid Eye Disease
AS-OCT of the Cornea in Thyroid Diseases
use the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye diseases (TED) patients and…
- Trial name
- NCT05241626
- Testing
- AS-OCT
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University
Pseudoexfoliation Syndrome, Biomechanical Parameters
Corneal Biomechanics, Optical Properties and Anterior Segment Structural Features in Patients With Pseudoexfoliation
The purpose of this study is to assess the effect of pseudoexfoliation syndrome on corneal biomechanics, optical clarity of the cornea, and anterior segment structural features.
- Conditions
- Pseudoexfoliation Syndrome, Biomechanical Parameters, Corneal Densitometry
- Trial name
- CorPEX (NCT06731530)
- Testing
- Pentacam-AXL, HD Analyzer, Corvis ST
- Where
- Greece
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Corneal Perforation
Role of AS-OCT in Assessment of Corneal Perforation
Assessment of healing of thin and perforated cornea after surgical treatment by anterior segment optical coherence tomography
- Trial name
- OCT (NCT06422897)
- Testing
- anterior segment optical coherence tomography
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Minia University
Artifical Intelligence, Cataract
Development of a Mobile Terminal-Based Intelligent Detection System for Multiple Anterior Segment Diseases of the Eye
This is a multi-center, cross-sectional study evaluating a smartphone-based artificial intelligence (AI) system for anterior segment eye disease screening.
- Conditions
- Artifical Intelligence, Cataract, Pterygium, Keratopathy
- Trial name
- LENS (NCT07634913)
- Testing
- Smartphone-based on-device artificial intelligence system for anterior segment eye disease screening
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Keratoconus
Evaluation of the Keratoconic Cornea After Corneal Collagen Cross Linking.
Aim of work: To detect abnormal corneal thinning in keratoconus using pachymetry maps measured by high-speed anterior segment optical coherence tomography (OCT).
- Trial name
- NCT03879421
- Testing
- Accelerated corneal collagen cross linking
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Reham Mahmoud Abdelrahman
Active Noninfectious Uveitis Affecting the Posterior Segment
A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants
This study is researching an experimental drug called REGN7041 (also referred to as "study drug"). The study is focused on patients who have active inflammation inside of the eye without any signs of infection.
- Trial name
- TITAN (NCT07218770)
- Testing
- REGN7041
- Where
- 5 sites in United States
- Volunteers
- 1 people
- Sponsor
- Regeneron Pharmaceuticals
Keratoconus, High Myopia
Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging
The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.
- Trial name
- NCT06739018
- Testing
- pentacam scheimpflug tomography
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University