Clinical trials: Anterior Uveitis
Infectious Panuveitis, Infectious Iridocyclitis
Pathogen Detection in Infectious Uveitis
Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye.
- Trial name
- NCT04521673
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Anterior Uveitis, Panuveitis
Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis
The purpose of this phase 3 confirmatory study is to determine if difluprednate ophthalmic emulsion is effective in the treatment of treatment of uveitis.
- Trial name
- NCT00406887
- Testing
- Difluprednate Ophthalmic Emulsion
- Volunteers
- 140 people
- Sponsor
- Sirion Therapeutics, Inc.
Acute Anterior Uveitis
Proof of Concept Study to Evaluate Safety and Efficacy of LME636 in the Treatment of Acute Anterior Uveitis
The purpose of the study is to determine whether topical ocular administration of LME636 60 mg/mL is efficacious in resolving the ocular inflammation in the anterior chamber (AC) associated with acute anterior uveitis (AAU).
- Trial name
- NCT02482129
- Testing
- LME636 60 mg/mL ophthalmic solution, Dexamethasone 0.1% ophthalmic solution, LME636 Vehicle
- Volunteers
- 45 people
- Sponsor
- Alcon Research
Ocular Sarcoidosis, Panuveitis
Ocular Sarcoidosis Open Label Trial of ACTHAR Gel
Treatment with ACTHAR Gel will result in a reduction of ocular inflammation in patients with active ocular sarcoidosis that requires systemic immunosuppressant therapy (hypothesis)
- Conditions
- Ocular Sarcoidosis, Panuveitis, Anterior Uveitis
- Trial name
- NCT02725177
- Testing
- Repository Corticotropin Injection, Repository Corticotropin Injection -Treatment Extension
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The Cleveland Clinic
Anterior Uveitis
Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Non-Infectious Anterior Uveitis
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to prednisolone acetate…
- Trial name
- EGP-437-006 (NCT02517619)
- Testing
- Dexamethasone Phosphate Ophthalmic Solution, Prednisolone Acetate Ophthalmic (1%)
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Sarcoidosis, Tuberculosis
The Serum Angiotensin Converting Enzyme and Lysozyme Levels in Patients Non-infectious and Infectious Uveitis
This study evaluates the significance of differences in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of other autoimmune inflammatory and infectious diseases.
- Trial name
- uveitis (NCT02627209)
- Testing
- spectrophotometric assay, radial immunodiffusion
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Ozlem Sahin
Behcet Disease
Behcet Disease Patients With Pulmonary Endoarterectomy: Outcomes of Program of Inspiratory Msucle Trianing
physical complications are common in Behcet disease patients with pulmonary endoarterectomy, so outcomes of program of inspiratory msucle trianing must be investigated
- Trial name
- NCT07662603
- Testing
- inspiratory muscle trianing
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Uveitis, Posterior, Uveitis, Intermediate
A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with clinically quiescent non-infectious uveitis
- Conditions
- Uveitis, Posterior, Uveitis, Intermediate, Panuveitis
- Trial name
- LUMINATE (NCT00404742)
- Testing
- LX211
- Where
- 41 sites in United States, Austria and 5 more
- Volunteers
- 232 people
- Sponsor
- Lux Biosciences, Inc.
Behcet's Disease, Vasculitis
Induction Therapy With Anti-TNFα vs Cyclophosphamide in Severe Behçet Disease
Behçet's disease (BD) is a systemic vasculitis of arterial and venous vessels of any size, involving young patients (from 15 to 45 years). BD significantly increases morbidity and mortality.
- Trial name
- ITAC (NCT03371095)
- Testing
- Infliximab, Cyclophosphamide
- Where
- 27 sites in France
- Volunteers
- 53 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-Infectious Anterior Uveitis
Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis
The purpose of this study is to determine the efficacy, safety, and tolerability of dexamethasone sodium phosphate Visulex (DSP-Visulex) after repeated-dose administration in patients with acute anterior uveitis.
- Trial name
- NCT02309385
- Testing
- 8% Dexamethasone Sodium Phosphate - Visulex, 15% Dexamethasone Sodium Phosphate - Visulex, Prednisolone Acetate (1%) Eye Drops
- Where
- 6 sites in United States
- Volunteers
- 44 people
- Sponsor
- Aciont Inc
Spondylarthropathies, Spondylitis, Ankylosing
Methotrexate in the Treatment of Axial Spondyloarthritis
The goal of this study is to evaluate the efficacy of oral methotrexate for the treatment of active axial spondyloarthritis (early ankylosing spondylitis or spondyloarthritis with sacroiliitis).
- Trial name
- NCT00298012
- Testing
- Methotrexate
- Where
- 5 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Rheumatism Foundation Hospital
Anterior Uveitis
A Phase 2 Study of VVN461 Ophthalmic Solution for Noninfectious Anterior Uveitis
This is a multicenter, double-masked, randomized, active-controlled, parallel-comparison study conducted at sites in the China in subjects with Noninfectious Anterior Uveitis
- Trial name
- NCT06679153
- Testing
- VVN461 Ophthalmic Solution 1.0%, VVN461 Ophthalmic Solution 0.5%, Prednisolone acetate
- Where
- China
- Volunteers
- 89 people
- Sponsor
- VivaVision Biotech, Inc
Behcet's Disease, Albumin
Behçet and LDH/Albumin
ABSTRACT Objective: To investigate whether the lactate dehydrogenase to albumin ratio can be used as a parameter to determine disease severity in Behçet's disease, an inflammatory disease, by comparing it to healthy controls.
- Conditions
- Behcet's Disease, Albumin, Lactate Dehydrogenase, Disease Severity
- Trial name
- NCT06276829
- Testing
- LDH/albumin ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Behçet Disease, Physiopathology
Understanding the Role of Oral Microbiota in Behçet's Disease (BEHCETBIOT)
Behçet's disease (BD) is a systemic vasculitis that affects, especially, young people. Although its etiology remains unexplained, data suggest that the inflammatory response during BD results from a disruption of the homeostasis…
- Conditions
- Behçet Disease, Physiopathology, Microbiota, Oral Microbiota
- Trial name
- BEHCETBIOT (NCT04959435)
- Testing
- biological samples collection
- Where
- 2 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Clermont-Ferrand
Behcet's Disease, Uveitis
Immunogenetic Mechanisms in Behcet's Disease
Background: Uveitis, the inflammation of the interior of the eye, is responsible for numerous new cases of legal blindness every year.
- Trial name
- NCT01109433
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Eye Institute (NEI)
Anterior Uveitis, Intermediate Uveitis
Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis
This study investigates the variations in the retinal nerve fiber layer (RNFL) thickness during uncomplicated anterior and intermediate uveitis, respectively.
- Trial name
- NCT02879084
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- CHU de Quebec-Universite Laval
Behcet Disease, Cranial Nerve Disorder
Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters
The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features.
- Trial name
- NCT07135063
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Uveitis
A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis
The reason for this study is to see if the study drug baricitinib given orally is safe and effective in participants with active juvenile idiopathic arthritis (JIA)-associated uveitis or chronic anterior antinuclear…
- Trial name
- NCT04088409
- Testing
- Baricitinib, Adalimumab
- Where
- 20 sites in France, Germany and 3 more
- Volunteers
- 30 people
- Sponsor
- Eli Lilly and Company
Non-infectious Uveitis
Safety and Efficacy of AIN457 in Noninfectious Uveitis
This study was performed to evaluate the efficacy and safety of AIN457 for patients with active uveitis that requires systemic immunosuppression.
- Trial name
- NCT00685399
- Testing
- AIN457, AIN 457
- Where
- 23 sites in United States, Germany
- Volunteers
- 76 people
- Sponsor
- Novartis Pharmaceuticals
Uveitis, Anterior, Juvenile Idiopathic Arthritis
Imaging Based Uveitis Screening for Children With Juvenile Idiopathic Arthritis
This study seeks to describe, for children undergoing uveitis surveillance following a new diagnosis of juvenile idiopathic arthritis, the feasibility metrics of undertaking a randomised comparative study of routine slit lamp…
- Trial name
- UVESCREEN1 (NCT05984758)
- Testing
- AS-OCT imaging, Slit lamp examination
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Institute of Child Health