Clinical trials: Anterior Wall; Prolapse, Vaginal
Anterior Vaginal Wall Prolapse
Small Stitch Study
A descent of the anterior vaginal wall is the most common form of female pelvic organ prolapse (POP). Although anterior colporrhaphy (AC) is accepted worldwide as a "standard procedure", its exact steps are not well standardized.
- Trial name
- NCT02469584
- Testing
- small stitch anterior colporrhaphy
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Pelvic Organ Prolapse
Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse
This study will evaluate the effect of pessary therapy, with and without Solifenacin (Vesicare), on symptoms of over active bladder and bladder function in women with overactive bladder symptoms and pelvic organ prolapse.
- Trial name
- PESSARY (NCT01092624)
- Testing
- Solifenacin, Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hartford Hospital
Vaginal Prolapse, Cystocele
Comparative Study of Mesh Versus No Mesh in Prolapse Surgery
Hypothesis / aims of study A RCT has shown that results of prolapse repair via vaginal approach could be improved when a polypropylene mesh is used as tissue support (1).
- Trial name
- NCT00153257
- Testing
- Ugytex
- Where
- France
- Volunteers
- 162 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anterior Vaginal Wall Prolapse With/Without Apical/Uterine Descent
Multicenter, Prospective, Non-randomized, Single-arm, Interventional Study for the Evaluation of the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
A prospective, single arm, multi-center clinical study to evaluate the safety and performance of the SRS (Lyra Medical) vaginal mesh in POP patients
- Trial name
- NCT03195361
- Testing
- SRS - Self Retaining Support system
- Where
- 3 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Lyra Medical Ltd.
Anterior Vaginal Wall Prolapse, Vaginal Apex/Uterine Prolapse
Demonstrate the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
A prospective, single arm, pre-market, multi-center clinical study to evaluate the safety and performance of the SRS (Lyra Medical) vaginal mesh in POP patients
- Trial name
- NCT02209337
- Testing
- SRS
- Where
- 3 sites in Hungary, Israel
- Volunteers
- 20 people
- Sponsor
- Lyra Medical Ltd.
Catheter Related Complication, Anterior Vaginal Wall Prolapse
Comparison of 1 Versus 2 Days Post-Operative Catheterization After Anterior Colporrhaphy
Patients who undergo anterior vaginal wall plastic surgery and place the bladder catheter during surgery are selected. The purpose of the study is to evaluate the presence of statistically significant differences in bladder…
- Trial name
- NCT06429228
- Testing
- Catheter removal after surgery
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Anterior Vaginal Wall Prolapse, Cystocele
Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
The purpose of this study is to evaluate the success rate of cystocele repair using polypropylene mesh or porcine dermis compared to that of anterior colporrhaphy in a prospective randomized fashion.
- Conditions
- Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
- Trial name
- OARS (NCT01393171)
- Testing
- Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse
The Influence of Using Vascularized Vaginal Flap on the Efficacy of Mesh-augmented Sacrospinous Hysteropexy
This is a prospective randomized controlled trial designed to compare the effectiveness and safety of two methods of pelvic floor reconstruction in patients with pelvic organ prolapse (POP): sacrospinous hysteropexy (SSHP) with…
- Trial name
- NCT06494982
- Testing
- Sacrospinous hysteropexy with the synthetic mesh, vaginal flap and anterior colporrhaphy, Sacrospinous hysteropexy with the synthetic mesh and anterior colporrhaphy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Saint Petersburg State University, Russia
Pelvic Organ Prolapse, Uterine Prolapse
Does a High BMI Affect Supervised Pelvic Floor Muscle Training for Improving Symptoms in Women With Various Stages of Pelvic Organ Prolapse?
The trial design is a quasi-experimental cohort trial that includes women referred for pelvic organ prolapse specific physiotherapy.
- Conditions
- Pelvic Organ Prolapse, Uterine Prolapse, Anterior Wall; Prolapse, Vaginal, Posterior Wall; Prolapse, Vaginal
- Trial name
- NCT04009694
- Testing
- Pelvic Floor Muscle training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salford
Vaginal Prolapse
Comparison Between Transvaginal Mesh and Traditional Surgery for Pelvic Organ Prolapse
Pelvic organ prolapse is characterized by a lack of pelvic floor support causing the pelvic organs and vaginal walls to protrude.
- Trial name
- NCT00566917
- Testing
- Anterior colporrhaphy, Anterior PROLIFT
- Where
- 53 sites in Denmark, Finland and 2 more
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Prolapse
Surgical Study Comparing 2 Procedures for the Treatment of a Dropped Bladder
The purpose of this study is to determine whether vaginal repair or abdominal repair is the procedure of choice for the surgical management of a prolapsed bladder.
- Trial name
- NCT00271102
- Testing
- anterior vaginal repair (colporrhaphy), abdominal paravaginal defect repair
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Geisinger Clinic
Pelvic Organ Prolapse
SIS Graft and Traditional Repair in Vaginal Wall Prolapse
The objective of this study is to evaluate surgical treatment of anterior vaginal wall prolapse using the sis graft or traditional repair. This a randomized and prospective study.
- Trial name
- NCT00827528
- Testing
- Traditional correction of anterior vaginal wall prolapse, Biologic Graft (SIS)
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Federal University of São Paulo
Pelvic Organ Prolapse, Cystocele
Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS
Surgical correction of the prolapse in the anterior compartment remains one of the major challenges in urogynecology. Paravaginal defect in level II of vaginal fixation results in the majority of cystoceles.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Cystocele and Incomplete Uterovaginal Prolapse
- Trial name
- STARS (NCT05602246)
- Testing
- Transobturator cystocele repair, Anterior colporrhaphy
- Where
- 8 sites in Czechia, Slovakia
- Volunteers
- 592 people
- Sponsor
- Charles University, Czech Republic
Anterior Vaginal Wall Prolapse
Mesh Repair of Anterior Vaginal Wall Prolapse
The purpose of this study is to determine whether reenforcement with polypropylen mesh compared with traditional anterior colporrhaphy for anterior vaginal wall prolapse results in fewer recurrences.
- Trial name
- NCT00420225
- Testing
- Low-weight prolypropylene mesh
- Where
- Finland
- Volunteers
- 202 people
- Sponsor
- Tampere University
Vaginal Prolapse
A Randomised, Controlled Study of Bimesh, Pelvicol for Vaginal Wall Prolapse
Anterior vaginal wall prolapse is a common problem. Until now many different surgical techniques have been evaluated but so far recurrence is often still observed.
- Trial name
- NCT00442247
- Testing
- Pelvicol
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Pelvic Organ Prolapse
Anterior Vaginal Wall Repair With Mesh in Combination With TVT-O to Reduce Urinary Stress Incontinence
Urinary stress incontinence is defined as leakage of urine during stress. Urinary stress incontinence is a health problem with social, economic and psychological consequences.
- Trial name
- NCT01507714
- Testing
- Preventive transobturator tension free vaginal tape
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel
Anterior Vaginal Wall Prolapse, Pelvic Organ Prolapse
Transobturator Lateral Suspension in Anterior Colporrhaphy
Anterior colporrhaphy (AC) is commonly used for anterior vaginal wall prolapse, but suffers high recurrence rates. This randomized trial assessed whether adding transobturator lateral suspension (TOLS) to AC decreases objective…
- Trial name
- TLSAC (NCT07144397)
- Testing
- TOLS
- Where
- Slovenia
- Volunteers
- 44 people
- Sponsor
- University Medical Centre Maribor
Stress Urinary Incontinence
Correction of Asymptomatic 2nd Degree Cystocele in Patient With Stress Incontinence
The aim of our study is to assess the value of concomitant surgical correction of asymptomatic grade II anterior vaginal wall prolapse with the placement of midurethral sling for treatment of female patients with stress…
- Trial name
- NCT03296748
- Testing
- trans-obturator tape inside-out usingsoft tapes., anterior colporraphy
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Kasr El Aini Hospital
Vaginal Prolapse
Anterior Vaginal Wall Reconstruction
The purpose of this study is to assess the effectiveness of the polypropylene tape in preventing cystocele recurrence when placed underneath the bladder base as a concomitant measure to the anterior colporrhaphy procedure.
- Trial name
- NCT00571350
- Testing
- tvt-o operation, tvt o operation
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Hippocration General Hospital