Clinical trials: Anterior Wall Myocardial Infarction
ST-elevation Myocardial Infarction
Cooling in Myocardial Infarction
The primary goal in the treatment of acute myocardial infarction is to reperfuse the ischemic myocardium to reduce infarct size.
- Trial name
- STATIM (NCT01777750)
- Testing
- EMCOOLS flex pad; Philips Innercool RTx
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Acute Anterior Wall Myocardial Infarction
Autologous Stem Cell Transplantation in Acute Myocardial Infarction
Objectives Intracoronary transplantation of different cell populations have been used in acute myocardial infarction (AMI) with promising results.
- Trial name
- NCT00199823
- Testing
- Intracoronary aotologous stem cell transplantation
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Anterior Myocardial Infarction
Effects of Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) Therapy on miRNAs Expression and Absolute Microvascular Resistance by Continuous Thermodilution in ST-segment Elevation Myocardial Infarction (STEMI) Patients: PiCSO-STEMI TRIAL
In this study we pretend to determine the molecular (miRNAs expression, angiogenic and inflammatory biomarkers) and microcirculatory (assessed by the innovative continuous intracoronary thermodilution technique) effects of PiCSO…
- Trial name
- PiCSO-STEMI (NCT05644925)
- Testing
- PiCSO Impulse System, Percutaneous Coronary Intervention (PCI)
- Sponsor
- Fundacio Privada Mon Clinic Barcelona
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial
The purpose of this research study is to evaluate whether using the the IMPELLA® CP System temporary circulatory assist device for 30 minutes prior to a catheterization procedure has the potential to reduce the damage to the…
- Trial name
- DTU-STEMI (NCT03947619)
- Testing
- Impella CP® placement prior to reperfusion with Primary PCI
- Where
- 63 sites in United States, Canada and 4 more
- Volunteers
- 527 people
- Sponsor
- Abiomed Inc.
Intravascular Imaging and Microvascular Obstruction
Study on the Improvement of Myocardial Microcirculation After Acute Anterior Myocardial Infarction
This study is a prospective, single-center, randomized controlled clinical trial. Ninety patients with anterior wall ST-segment elevation myocardial infarction (STEMI) who are planned for primary percutaneous coronary…
- Trial name
- NCT06154395
- Testing
- OCT-guided PCI, 60 MHz HD-IVUS-guided PCI, Angiography-guided PCI
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Harbin Medical University
Acute Myocardial Infarction
Effect of Shexiang Tongxin Dropping Pills on Microcirculation in Patients With AMI
This study is a randomized, controlled clinical trial. Evaluation of microcirculation resistance by index of microcirculation resistance to explore the protective effect of Shexiang Tongxin dripping pills on microcirculation in…
- Trial name
- NCT04952259
- Testing
- Shexiang Tongxin Dropping Pills + routine treatment, routine treatment
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Myocardial Infarction (MI)
Hyperoxemic Oxygen Therapy in Patients With Acute Anterior Myocardial Infarction
The HOT-AAMI study investigates the efficacy of supersaturated oxygen therapy (SSO2) as an adjunct to standard percutaneous coronary intervention (PCI) with stent implantation in patients suffering from acute anterior myocardial…
- Trial name
- HOT-AAMI (NCT06742684)
- Testing
- PCI with following SSO2 Therapy
- Sponsor
- IHF GmbH - Institut für Herzinfarktforschung
STEMI - ST Elevation Myocardial Infarction, Anterior MI
Observational Registry to Evaluate Real World Usage of PiCSO Impulse System in STEMI Patients as Part of Post-marketing Surveillance
A prospective, multicenter, single-arm, open label registry of commercially treated patients with PiCSO Impulse System.
- Trial name
- PiCSO-AMI-IV (NCT04566289)
- Testing
- PiCSO
- Where
- Germany
- Sponsor
- Miracor Medical SA
Anterior Myocardial Infarction, Heart Failure
Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients
The main purpose of this study is to compare the myocardial protection effect of intravenous metoprolol combined with remote ischemic conditioning (RIC) and single treatment before reperfusion in Chinese patients with anterior…
- Trial name
- NCT03579914
- Testing
- Metoprolol Injectable Product, Romote Ischemic Conditioning (RIC), Metoprolol & RIC
- Where
- 16 sites in China
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Heart Injuries
Subclinical Hypothyroidism and Acute Anterior Myocardial Infarction: Is it Cardio-protective or Not?
The study plans to investigate whether recovery of the heart function after acute anterior myocardial infarction is dependent upon improvement in thyroid gland functioning.
- Trial name
- NCT03017157
- Testing
- Echo-cardiogram, Blood test
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Coronary Artery Disease, Acute Myocardial Infarction
Collateral Circulation to LAD and Wellens Sign
Overall Aim Coronary artery disease significantly contributes to morbidity and mortality in the United States. Atherosclerotic disease can lead to stenosis of the coronary arteries and subsequent cardiac hypoperfusion.
- Conditions
- Coronary Artery Disease, Acute Myocardial Infarction, Acute Myocardial Infarction of Anterior Wall, Collateral Circulation, Any Site
- Trial name
- NCT03707626
- Testing
- Wellens Sign
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Coney Island Hospital, Brooklyn, NY
STEMI - ST Elevation Myocardial Infarction, Anterior Wall Myocardial Infarction
A Study to Evaluate the Safety and Efficacy of PiCSO in Anterior STEMI Patients
The objective of this study is to assess the safety and efficacy of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) as adjunct to percutaneous coronary intervention (PCI) compared to PCI in the setting of acute…
- Trial name
- PiCSO-AMI-II (NCT05497011)
- Testing
- PiCSO Impulse System
- Sponsor
- Miracor Medical SA
Patient With Anterior Myocardial Infarction
Efficacy and Safety of Low Dose Rivaroxaban in Patients With Anterior Myocardial Infarction
Despite the use of guideline directed optimal medical therapy, 12% of patients with stable coronary heart disease and 18% of patients with recent acute coronary syndrome experience recurrent major adverse cardiovascular events 1.
- Trial name
- NCT05744804
- Testing
- -group of patients(75 patients) will receive low dose rivaroxaban myocardial infarction plus (acetylsalicylic acid 75 mg and clopidogrel 75 mg, (acetylsalicylic acid 75 mg once daily orally and clopidogrel 75 mg once daily orally only)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Anterior Myocardial Infarction
TACTIC Coronary Thrombus Aspiration With Cath Rx In Anterior Myocardial Infarction: A Randomized Control Trial.
The aim of this study is to evaluate the impact of sustained thrombectomy with INDIGO ASPIRATION SYSTEM using CAT RX versus no thrombectomy during primary percutaneous coronary intervention (PPCI) on microvascular obstruction and…
- Trial name
- TACTIC (NCT06887413)
- Testing
- THROMBOASPIRATION WITH INDIGO SYSTEM
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Ceric Sàrl
ST Elevation Myocardial Infarction, Heart Failure
Effect of Levosimendan on Left Ventricular Systolic Function and Heart Failure After PCI in Patients With Acute Anterior Myocardial Infarction
Reperfusion therapy for acute ST segment elevation myocardial infarction (STEMI) can significantly reduce mortality, but patients may still have heart failure and adverse cardiovascular events due to massive myocardial loss.
- Trial name
- NCT04970238
- Testing
- Levosimendan
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhijun Sun
Myocardial Infarction
AMI-DC in Patients With Anterior Wall Myocardial Infarction
The purpose of this trial is to assess the safety of AMI-DC treatment. The participants who voluntarily sign the consent form will be screened according to the inclusion/exclusion criteria then allocated either to the…
- Trial name
- AMI-DC (NCT05554484)
- Testing
- Autologous peripheral blood-derived tolerogenic dendritic cells
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- The Catholic University of Korea
Anterior Myocardial Infarction
A Research Study to Evaluate the Safety and Preliminary Efficacy of SGC001 in Patients With Myocardial Infarction
The research study is being done to see if SGC001 can be used to treat people scheduled to undergo percutaneous coronary intervention for Anterior ST-segment Elevation Myocardial Infarction.
- Trial name
- NCT07091929
- Testing
- SGC001
- Where
- 4 sites in China
- Volunteers
- 38 people
- Sponsor
- Beijing Sungen Biomedical Technology Co., Ltd
Anterior Wall Acute Myocardial Infarction
Evaluation of Intracoronary Hyperoxemic Oxygen Therapy in Anterior Acute Myocardial Infarction Patients (IC-HOT)
The primary objective of the study is to collect confirmatory data supporting the safety and effectiveness of SSO2 Therapy in treatment of anterior acute myocardial infarction (AMI) patients who have undergone successful…
- Trial name
- IC-HOT (NCT02603835)
- Testing
- SSO2 Therapy
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- TherOx
STEMI, Anterior MI
Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction
The objective of this study is to assess efficacy and safety of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) therapy started post flow restoration but prior to stenting during percutaneous coronary…
- Trial name
- PiCSO-AMI-I (NCT03625869)
- Testing
- PiCSO
- Where
- 17 sites in Denmark, France and 4 more
- Volunteers
- 145 people
- Sponsor
- Miracor Medical SA
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function
The primary endpoint is to assess the safety and tolerability of Cenderitide (CD-NP) with the incidence of symptomatic hypotension being one of the key safety variables.
- Trial name
- BELIEVE III (NCT02071602)
- Testing
- CD-NP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic