Clinical trials: Anthocyanin Metabolism
Type 2 Diabetes
Effect of Soft Fruit on Postprandial Blood Glucose
Dietary strategies for alleviating health complications associated with type 2 diabetes (T2D) are being pursued as alternatives to pharmaceutical interventions.
- Trial name
- NCT02291250
- Testing
- Blackcurrants with polycal OGTT, Greencurrants with polycal OGTT, Blackcurrants with glucose OGTT
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Healthy, Metabolic Syndrome
Effect of Cherry Juice on Fat Oxidation and Cardio-metabolic Markers
The present study examined the effect of Montmorency tart cherry juice and FATMAX (intensity eliciting maximal fat oxidation) exercise on fat oxidation rates, body composition and blood-based cardio-metabolic markers.
- Trial name
- NCT02999256
- Testing
- Montmorency Tart Cherry Juice
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Hertfordshire
Hyperlipidemia
Bilberry Fruit and Black Rice Derived Anthocyanins on Lipid Status
The primary aim of this study is to directly compare the two major types of anthocyanins found in the diet (cyanidin-type and delphinidin-type) on lipid status in adults.
- Trial name
- NCT03213288
- Testing
- Delphinidin type anthocyanins, Cyanidin type anthocyanins
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Metabolic Syndrome
Pivotal Assessment of the Effects of Bioactive on Health and Wellbeing. From Human Genome to Food Industry
This is a multi-centre, randomised, double-blind, placebo-controlled, parallel-arm dietary intervention study. In total, 800 men and women at risk for Metabolic Syndrome (MS) will be recruited.
- Trial name
- PATHWAY-27 (NCT02702713)
- Testing
- Dairy BEF, Egg BEF, Bakery BEF
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Iron Deficiencies, Inflammation
Effect of Supplementation With Anthocyanins on Iron Metabolism in Female Swimmers
The study included 8-weeks supplementation of black chokeberry extract with 18% standardization of the anthocyanins content (dose 2×200 mg per day), or a placebo product that was made from chokeberry fiber.
- Conditions
- Iron Deficiencies, Inflammation, Oxidative Stress, Female Athlete Triad
- Trial name
- NCT06486623
- Testing
- Black chokeberry extract in capsules with 18% standardization of the anthocyanins content, Chokeberry fiber in capsules
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Poznan University of Physical Education
Overweight and Obesity
Effect of Açaí Juçara Consumption on Endothelial Function and Arterial Stiffness
This study evaluates the consumption of Açaí Juçara pulp in endothelial function and arterial stiffness in overwheight and obese individuals.
- Trial name
- NCT04434534
- Testing
- Hipocaloric Diet with Açaí Juçara, Hipocaloric Diet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Gout
Pharmacokinetics and Pharmacodynamics of Anthocyanins
The purpose of the study is to establish the pharmacokinetic parameters of cherry juice concentrate and identify its potential to alter inflammatory markers in gout patients.
- Trial name
- NCT03650140
- Testing
- Tart cherry extract 60 mL, Tart cherry extract 120 mL
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Anthocyanin Metabolism
Gastric pH and Anthocyanin Absorption
Anthocyanins are phytonutrients that provide blue, purple and red colors to fruits and vegetables. The purpose of the study is to determine whether absorption of anthocyanins occurs in the acid pH of the stomach and to determine…
- Trial name
- NCT01122160
- Testing
- omeprazole
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Diabetes, Insulin Resistance
Glycemic Index and Polyphenol Bioavailability of Potatoes
The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.
- Trial name
- GI (NCT01053793)
- Testing
- Glycemic response to different varieties of potatoes
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Guelph Food Research Centre
Glucose Intolerance, Glucose Metabolism Disorders
Acute Study of Anthocyanin-rich Bilberry and Polyphenol-rich Apple Extracts on Postprandial Glycaemic Response
Strategies to control chronic postprandial hyperglycaemia by optimizing the functionality of foods would strengthen efforts to reduce the risk of developing T2D in the general population.
- Trial name
- NCT04004182
- Testing
- Fruit bar with addition of polyphenols
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Bioavailability, Cardiovascular Disease
Bioavailability and Metabolism of Anthocyanins Following Acute Cranberry Consumption
This study hypothesis is that anthocyanins from cranberry juice are bioavailable and can be measured in blood and urine after a single acute consumption of cranberry juice.
- Trial name
- NCT00809900
- Testing
- Experimental
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tufts University
Hypertension, Hypercholesterolemia
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk Factors
The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods.
- Conditions
- Hypertension, Hypercholesterolemia, Type II Diabetes, Obesity
- Trial name
- NCT01564498
- Testing
- vegetable
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Guelph
Diabetes Mellitus，Type 2
Purified Anthocyanins Supplementation and High-Density Lipoprotein (HDL) Function
HDL function is impaired in patients with type 2 diabetes mellitus. Anthocyanin, a water-soluble compounds,is beneficial for vascular function by increasing nitric oxide (NO) bioavailability and decreasing oxidative stress.
- Trial name
- NCT02650726
- Testing
- Anthocyanin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Type 2 Diabetes
A Single Supplement of a Standardised Bilberry Extract Modifies Glycaemic Response
Dietary strategies for alleviating health complications associated with type 2 diabetes (T2D) are being pursued as alternatives to pharmaceutical interventions.
- Trial name
- NCT01245270
- Testing
- Bilberry capsule first, then control cap, Control capsule first then bilberry cap
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Aberdeen
Overweight, Healthy
Maximizing the Anti-inflammatory Effects of Strawberry Bioavailability
Primary objective is to determine if the efficacy of strawberries delivering polyphenols to prevent metabolic inflammation will be influenced by timing of consumption relative to meal intake.
- Trial name
- NCT01856153
- Testing
- Before meal, With Meal, After meal
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Overweight and Obesity, Healthy
Bioavailability of Blackberry Juice Anthocyanins
The main aim of this study is to evaluate the bioavailability of blackberry juice anthocyanins, with or without ethanol, in normal weight and overweight/obese adults.
- Trial name
- NCT02613715
- Testing
- Blackberry juice with 12% ethanol, Blackberry juice
- Where
- Portugal
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Dietary Exposure, Metabolic Disturbance
Influence of Tart Cherry Juice Intervention on Vascular Function
Diets containing fruit rich in anthocyanins have been shown (in meta-analyses) to be beneficial for health, but intervention trials have shown inconsistent results.
- Trial name
- NCT04840160
- Testing
- Cherry juice
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy Diet, Nutrition Aspect of Cancer
Metabolism and Absorption of Anthocyanins From Extract and Whole Blueberry Powder Confections in Healthy Adults
This trial studies how well a group of compounds found in blueberries called anthocyanins are absorbed into the body from 2 different types of blueberry confections (blueberry extract and whole blueberry powder).
- Trial name
- NCT04329962
- Testing
- Blueberry Powder Food Product, Dietary Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Insulin Sensitivity
The Effect of Blueberries on Enhancing Insulin Sensitivity in Humans: A Pilot Study
The purpose of this study is to evaluate the effect of blueberry powder on insulin sensitivity in obese, non-diabetic, and insulin resistant subjects.
- Trial name
- BLUEBERRY (NCT01005420)
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Anthocyanins
Inflammatory and Metabolic Responses to Long-term Dietary Supplementation With Anthocyanin-rich Blend
This study will investigate the capacity of an anthocyanin-rich blend (ACRB) dietary supplement to improve the alterations in lipid and glucose homeostasis triggered by consumption of a high-fat meal.
- Trial name
- NCT04637945
- Testing
- ACRB
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharmanex