Clinical trials: Anthocyanin Metabolism
Hyperuricemia, Insulin Resistance
Tart Cherry Juice and Markers of Inflammation, CVD, and Diabetes
In this study, the investigators recruited at-risk individuals (n=26) who were overweight (25.0-29.9 kg/m2) and obese (> 30.0 kg/m2) and likely to exhibit one or more conditions associated with Metabolic Syndrome (MetS).
- Conditions
- Hyperuricemia, Insulin Resistance, Obesity, CVD
- Trial name
- NCT03636529
- Testing
- Tart cherry juice
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Metabolic Syndrome, Insulin Resistance
Continuous Tart Cherry Juice Supplementation With Metabolic Syndrome Participants
The present study examined the effect of Montmorency tart cherry juice on functional and blood-based cardio-metabolic markers in humans with Metabolic Syndrome.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Hypertension
- Trial name
- NCT03619941
- Testing
- Montmorency Tart Cherry Juice
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Hertfordshire
Metabolism and Clearance of Cyanidin 3 Glucoside
Tracing the Path of an Ingested Plant Pigment Through the Human Body
This study will trace the path of a natural plant pigment, (cyanidin-3-glucoside; C3G), through the human body after consumption.
- Trial name
- NCT01106729
- Testing
- Cyanidin 3 glucoside
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Metabolic Syndrome
Effect of Mulberry Fruit Powder in Metabolic Syndrome
Metabolic syndrome is a raising concern globally, especially in developing countries such as Pakistan. To prevent its risk factors diet and lifestyle modification is major solution.
- Trial name
- NCT05956106
- Testing
- Black Mulberry Fruit Powder
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Healthy
Different Types of Fruits on Metabolic Function and Cognitive Performance
Primary objective is to assess the effect of the intake of different types of fruits on memory and attention. Secondary objective is to assess effect of intake of different types of fruits on metabolic markers, including glucose…
- Trial name
- WBB2 (NCT02736331)
- Testing
- Treatment 1, Treatment 2
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Diabetes Mellitus，Type 2
Purified Anthocyanins Supplementation in Type 2 Diabetes Mellitus
Anthocyanins, the water-soluble compounds that make plants appear different colors, have been shown to prevent insulin resistance, reduce the blood glucose and oxidative stress in rodents.
- Trial name
- NCT02317211
- Testing
- Anthocyanin
- Volunteers
- 70 people
- Sponsor
- Sun Yat-sen University
Insulin Resistance, Metabolic Syndrome X
The Health Effects of Blueberry Anthocyanins in Metabolic Syndrome (the CIRCLES-study)
The purpose of this study is to determine the dose-dependent impact of 6 month freeze-dried blueberry powder intake on insulin sensitivity and resistance, cardiovascular disease risk factors, and lung and cognitive function in…
- Trial name
- CIRCLES (NCT02035592)
- Testing
- Full dose blueberry, Half dose blueberry, Control
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 144 people
- Sponsor
- University of East Anglia
Nonalcoholic Fatty Liver Disease
Purified Anthocyanin and Nonalcoholic Fatty Liver Disease
Oxidative stress and inflammation are involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Anthocyanins from different plant foods have been shown to improve features of experimental NASH, such as oxidative…
- Trial name
- NCT01940263
- Testing
- Anthocyanin
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Shaoguan University
Dyslipidemia, Obesity
Chronic Effects of Freeze-Dried Strawberry Beverage on Cardiovascular Risk Factors
Berry anthocyanins have been shown to improve lipid profile in subjects with dyslipidemia while no such studies with whole strawberries have been reported in the US population.
- Trial name
- NCT01883401
- Testing
- Freeze-dried strawberries, Dietary fiber
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oklahoma State University
Metabolic Syndrome
The Effect of Blueberry Powder Supplementation on Cardiovascular Risk Factors in Subjects With the Metabolic Syndrome
The purpose of this study is to examine the effects of a blueberry powder on insulin sensitivity, blood pressure, and vascular reactivity in subjects with metabolic syndrome.
- Trial name
- NCT01399138
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Effect of Oryza Sativa l Extract to LPS, ZO-1, and Intestinal Microbiota in Obese Individuals
Background : Obesity prevalence rises among adults and leads to morbidity and mortality due to subsequent inflammation pathway activation.
- Trial name
- NCT04827628
- Testing
- Oryza Sativa Extract, Control
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Myocardial Infarction
Effects of Bilberry and Oat Intake After Type 2 Diabetes and/or MI
Background: Bilberries from Sweden, rich in polyphenols, have shown cholesterol-lowering effects in small studies, and the cholesterol-lowering properties of oats, with abundant beta-glucans and potentially bioactive…
- Trial name
- BioDiaMI (NCT03620266)
- Testing
- Bilberry, Bioprocessed oat bran, Combination bilberry/oats
- Where
- 8 sites in Denmark, Sweden
- Volunteers
- 900 people
- Sponsor
- Ole Frobert, MD, PhD
Insulin Resistance, Glucose Metabolism Disorders
Effect of Anthocyanins on Metabolic Profiles in Subjects With Pre-diabetes
Metabolic problems represent one of the major health concerns which are attractive for being addressed by nutritional interventions, as these are directly connected to dietary habits.Anthocyans possess cardiovascular disease…
- Conditions
- Insulin Resistance, Glucose Metabolism Disorders, Type 2 Diabetes, Lipid Metabolism Disorders
- Trial name
- NCT02689765
- Testing
- Anthocyanins
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Sun Yat-sen University
Coronary Disease, Inflammation
Metabolic, Vascular and Cognitive Effects of Treatment With Anthocyanins
The purpose of this study is to examine weather treatment with anthocyanins will affect lipid profile, markers of inflammation and oxidative stress in addition to antioxidative level in serum to the better in persons with…
- Conditions
- Coronary Disease, Inflammation, Cognitive Impairment
- Trial name
- NCT02409446
- Testing
- Anthocyanin
- Where
- Norway
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Postprandial Hyperglycemia
Glycaemic Index (GI) Evaluation of Carbohydrate-based Food with Functional Ingredients Derived from Food Sources
In Singapore, the Ministry of Health has declared a "War on Diabetes" and major efforts will be made to develop and deploy programs to prevent diabetes.
- Trial name
- NCT03989674
- Testing
- Anthocyanin
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Obesity
Cherries Role in Gut Microbiota-liver-brain Function
Sweet cherries (Prunus avium) are a good source of bioactive compounds including dietary fiber and phytochemicals which have been credited with multiple health benefits, including anti-inflammatory and antioxidant properties as…
- Trial name
- NCT05586386
- Testing
- Cherry group
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Type 2 Diabetes
Study of Oral Anthocyanins on Insulin Resistance
Dietary strategies for alleviating the metabolic complications such as diabetes associated with obesity are actively being pursued as alternatives to pharmaceutical interventions The genus Vaccinium (e.g.
- Trial name
- NCT01180712
- Testing
- Mirtoselect
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Aberdeen
Metabolic Syndrome, Inflammation
Impacts of Aronia on Inflammation and the Gut Microbiome
The overall goal of this project is to determine the inflammation lowering impact of anthocyanin-rich Aronia berries. Inflammation is an underlying mechanism driving the development of several diseases.
- Conditions
- Metabolic Syndrome, Inflammation, Hypertriglyceridemia, Obesity
- Trial name
- NCT04128839
- Testing
- Aronia berry juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Montana State University
Healthy
Metabolism of Anthocyanins and Heart Health
This study aims to find out if consuming a single dose of blueberries, rich in anthocyanins, within an energy dense meal, improves blood vessel function and biomarkers of heart health.
- Trial name
- AMP (NCT03869086)
- Testing
- Freeze dried blueberry powder
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Postprandial Hyperglycemia, Lipidemia
Black Rice Anthocyanin in Mixed Meals: Influence on Postprandial Glycaemic and Lipid Responses Among Healthy Individuals
The diabetes epidemic is a pertinent concern globally. The prevalence of this metabolic disease among adults had been disclosed by the World health Organisation (WHO), reporting a total of 422 million diabetic adults and 3.7…
- Trial name
- NCT04063137
- Testing
- Anthocyanin fortified bread with beef patty (35% fat)
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National University of Singapore