Clinical trials: Anti-Aging
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Skin Condition, Skin Hydration
Efficacy Test of a Moisturizing and Anti-aging Facial Mask
The objective of this study is to evaluate the effect of Moisturizing facial mask and Anti-aging facial mask on human skin condition improvement.
- Conditions
- Skin Condition, Skin Hydration, Anti Skin Aging
- Trial name
- NCT07622160
- Testing
- Hydrating Repairing Mask, Anti-aging Rejuvenating Mask
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Ageing Signs, Cognitive Decline
Anti-Ageing Health Supplement From Ginger Extracts
This study examines the development and efficacy of a health supplement derived from ginger using water extraction. Designed to address aging-related issues such as muscle loss (sarcopenia) and cognitive decline, the capsule's…
- Conditions
- Ageing Signs, Cognitive Decline, Musculoskeletal
- Trial name
- NCT06828783
- Testing
- ginger extract
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Systemic Inflammation (hsCRP), Healthy Aging
Evaluation of AppleX™ Apple Extract on Anti-Inflammatory and Healthy Aging Effects
The goal of this clinical trial is to learn if AppleX™ Apple Extract can help lower systemic inflammation in adults aged 45-70 with signs of low-grade inflammation.
- Conditions
- Systemic Inflammation (hsCRP), Healthy Aging, Vitality, Healthy Adult Participants
- Trial name
- NCT07678346
- Testing
- Apple Extract
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Aging
To Evaluate the Efficacy and Safety of NMN as an Anti-ageing Supplement in Middle Aged and Older (40-65 Years) Adults
It will be a two-part study. Part I will be six arms; randomized, double blind, parallel design, placebo-controlled dose ranging study. Part II will be open-label single dose study at the highest dose.
- Trial name
- NCT04823260
- Testing
- Nicotinamide Mononucleotide
- Where
- 2 sites in India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abinopharm, Inc
Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin
Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin
This study is a single-center, prospective, split-face self-controlled pilot trial designed to evaluate the anti-aging and whitening efficacy of the "Deep Microspicule Cream" (containing patented crystal microspicules…
- Trial name
- NCT07774260
- Testing
- Deep Microspicule Cream
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Healthy Aging, Anti Aging
iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional…
- Trial name
- VITAL (NCT07407894)
- Testing
- Bifidobacterium adolescentis iVS-1
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Skin Aging
A Randomized, Double-blinded, Placebo Controlled, Monocentric Study to Evaluate the Anti-ageing and Skin Brightening Benefit of the Test Product in Healthy Female Subjects
Every day the cells of the outer layer of skin die off, shed, and regenerate. When young, skin cells turn over quickly, but that turnover rate begins to slow with age, beginning as early as twenties.
- Trial name
- NCT04276753
- Testing
- Terminalia Chebula Fruit Extract
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ratan K. Chaudhuri
Aging
Targeting Aging and Promoting Longevity with Exogenous Nucleotides (TALENTs)
To investigate the effects of dietary nucleotides (NTs) as an anti-aging supplement, a clinical trial is carried as a randomized, double-blind, parallel design, placebo-controlled.
- Trial name
- NCT05243108
- Testing
- dietary nucleotides
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Peking University
Aging
Evaluation of Anti-aging Performance and Tolerance of a Hyaluronic Acid-based Filler NCTF135HA®
The NCTF135HA medical device from Laboratoires FILL-MED by FILORGA Company is an injectable solution for the treatment of wrinkles and biorevitalization of injected mature skin using a multi-injection technique with CE marking.
- Trial name
- HEBE2 (NCT05609617)
- Testing
- injection, Cream application
- Where
- France
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Laboratoires FILLMED
Inflammation, Skin Abnormalities
Effects of Bend Beauty's Anti-Aging Formula on Inflammatory Markers
This is a phase IV, randomized, double-blind, placebo-controlled, three-arm, parallel intervention study including three groups of 25 subjects between 35-65 years of age, treated with either Bend Beauty's Anti-Aging Formula, fish…
- Conditions
- Inflammation, Skin Abnormalities, Skin Pigment, Inflammatory Response
- Trial name
- BENCHMARK (NCT03862872)
- Testing
- Anti-Aging Formula, Control Fish Oil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bend Beauty Inc.
Aging
Effects of NAD3 Supplementation on Biomarkers of Aging
This is a randomized, parallel-group, placebo-controlled, clinical trial in middle-aged and older male and female subjects from Ohio. Subjects will take an over-the-counter dietary supplement or a placebo for 12 weeks.
- Trial name
- NCT04276948
- Testing
- NAD3
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Healthy Volunteers
Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?
The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease.
- Trial name
- NCT01752868
- Testing
- Supplement
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Skin and Subcutaneous Tissue Disorders
Topical Preparation of Pomegranate and Ginkgo Biloba for Anti-aging Activities
As the quality of life improves, people are seeking to look as young as they feel. Ginkgo biloba (GB) and Pomegranate (PG) extract can be used to create efficacious topical anti-aging products.
- Trial name
- NCT03772418
- Testing
- Cream Base, Pomegrante and Ginkgo biloba group
- Where
- 3 sites in Egypt, Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahmed A. H. Abdellatif
Skin Quality, Lips Quality
Evaluation of the Effects of an Oral Supplementation Containing Hyaluronic Acid
This is a single center, double-blind, randomized, placebo-controlled study, performed on two parallel groups. A total of 130 adult female subjects meeting specific inclusion/exclusion criteria will be included in order to have…
- Conditions
- Skin Quality, Lips Quality, Persistence of the Effect
- Trial name
- NCT06774742
- Testing
- HAFS Supplementation
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- TS Biotech - Shandong Tiansheng Biotechnology Co., Ltd
Healthy
Efficacy and Tolerance Evaluation of a Topical "Revitalizing" Face Day Cream
Aim of the study was to evaluate clinically and by non-invasive instrumental evaluations the "revitalizing" activity of a face cream applied twice a day, morning and evening, for an uninterrupted period of 8 weeks, by healthy…
- Trial name
- NCT02230397
- Testing
- plantaricin a (active product)
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Ageing, Photo-aging
Effects of Isoflavone Combined With Astaxanthin on Skin Aging
Photoaging is caused by the superposition of chronic ultraviolet (UV)-induced damage on the intrinsic aging process, and accounts for the majority of age-associated changes in skin appearance.
- Trial name
- NCT02373111
- Testing
- Isoflavone, Astaxanthin
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Skin Aging
Evaluation of the Anti-aging Efficacy of a Novel Skin Health Product
The aim of this study is to investigate the effect of cosmetic products with two different concentrations of the active on skin aging and in acting on the mitochondrial health of skin in comparison to a placebo product.
- Trial name
- NCT05300984
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Aging, Well Aging
Evaluation of Anti-oxidant, Anti-aging and Wellbeing Effects of a Novel Nutraceutical Formulation (HealthSpan)
The study was designed as a randomized, placebo-controlled trial with follow-up at 3 months. The study is in accordance with the Declaration of Helsinki and was approved by the Institutional Bioethical Committee of the National…
- Conditions
- Aging, Well Aging, Oxidative Stress
- Trial name
- HealthSpan (NCT05202652)
- Testing
- HealthSpan
- Where
- Greece
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- National Hellenic Research Foundation