Clinical trials: Anti-aging
Obesity, Overweight
Can Intermittent Fasting Mimic the Metabolic and Cardiovascular and Anti-aging Effects of Calorie Restriction?
The purpose of Intermittent Fasting study is to investigate whether intermittent fasting could decrease the chronic inflammation levels in overweight/obese people.
- Trial name
- IF (NCT01964118)
- Testing
- Intermittent Fasting group, control group
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Skin Smoothness, Radiance
Clinical Case Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment on Healthy Females with Fitzpatrick Skin Types V and VI
This single-center, open-label, clinical case trial was conducted to evaluate the efficacy and tolerability of a topical facial treatment when applied by a license esthetician in clinic in a series of 3 sessions with 1 month…
- Conditions
- Skin Smoothness, Radiance, Overall Appearance
- Trial name
- NCT06633731
- Testing
- Biocellulose Mask, Post Procedure Cream, Gentle Cleanser
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Aging, Dry Skin
Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Aging
This is a single-center, double-blinded, placebo-controlled, split-face, prospective clinical study to evaluate the anti-ageing efficacy and safety of a topical cosmetic formulation containing a botanical extract.
- Trial name
- NCT07780799
- Testing
- Cosmetic Topical Formulation 1, Cosmetic Base of Topical Formulation 1, Cosmetic Topical Formulation 2
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Uveitis, Iritis
Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications
Retinal optical coherence tomography (OCT) is an established technology which enables a detailed cross-sectional visualization of the retinal micro-anatomy, and an objective measurement of its thickness in-vivo.
- Conditions
- Uveitis, Iritis, Iridocyclitis, Anterior Uveitis
- Trial name
- NCT00476593
- Testing
- Diclofenac, Dexamethasone
- Where
- 2 sites in Norway
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Frailty
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Aging Frailty
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Aging Frailty
- Trial name
- NCT05018767
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 86 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Skin, Aging
The Effect of Autologous Stromal Vascular Fractions on Skin Regeneration
The purpose of this study is to observe whether the transplantation of autologous stromal vascular fraction (SVF) in adipose tissue is safe and its effect on improving skin regeneration.
- Trial name
- NCT03189628
- Testing
- stromal vascular fraction, Saline
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Genetics, Skin Aging
Relationship of Skin Related SNP to Topical Skin Care Product
Demonstrate the relationship between single nucleotide polymorphisms (SNP) and response to a topical skin care product.
- Trial name
- NCT03446079
- Testing
- Topical Anti Aging Cream
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- HelicalCodeMD
Skin Aging
A Randomized, Double-blinded, Placebo Controlled, Monocentric Study to Evaluate the Anti-ageing and Skin Brightening Benefit of the Test Product in Healthy Female Subjects
Every day the cells of the outer layer of skin die off, shed, and regenerate. When young, skin cells turn over quickly, but that turnover rate begins to slow with age, beginning as early as twenties.
- Trial name
- NCT04276753
- Testing
- Terminalia Chebula Fruit Extract
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ratan K. Chaudhuri
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Aging Well
Effect of Anti-aging Therapy on Fitness Enhancement in Perimenopausal Women
Aging is an important fact to consider from the woman's health perspective. One of the most significant stages of aging is menopause, in which involves physical, psychological, and social changes in life
- Trial name
- NCT06224465
- Testing
- aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Facial Wrinkles, Skin Aging
Anti-Wrinkle Efficacy of a Syringic Acid-Containing Emulsion
This randomized, double-blind, split-face controlled study was conducted to evaluate the anti-wrinkle efficacy and safety of a Syringic acid-containing emulsion in healthy female subjects.
- Trial name
- NCT07850817
- Testing
- Synox-containing Emulsion, Control Emulsion
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BioSpectrum Inc
COPD
Exploring the Anti-ageing Effects of Metformin in COPD
Prospective, multicentre, double-blind, placebo-controlled, randomised, prospective clinical trial comparing the effect of metformin 850 mg twice daily with placebo in COPD patients with evidence of emphysema (by CT scan or…
- Trial name
- AMICO (NCT06999343)
- Testing
- Metformin 850Mg Tab
- Volunteers
- 212 people
- Sponsor
- Fundación Instituto de Investigación Sanitaria de Navarra
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Skin Aging
Effectiveness of a Bilayering Serum and Cream Containing GABA, DMAE, Cysteamine, and Bakuchiol for Skin Whitening and Anti-Aging
This study aims to evaluate the clinical efficacy and safety of a multi-functional bilayering skincare regimen-consisting of a serum and cream-for improving skin brightness and reducing wrinkles.
- Trial name
- NCT07477288
- Testing
- GABA, DMAE, Cysteamine
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Wrinkles, Fine Lines
Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.
This is a randomized, double-blind, comparative, two-arm, prospective, interventional, multi-centre clinical study to evaluate the safety, efficacy, and in-use tolerability of test products, standardized saffron extract capsules…
- Conditions
- Wrinkles, Fine Lines, Hyperpigmentation, Dark Spots
- Trial name
- GLOW (NCT07324759)
- Testing
- Standardized Saffron Extract (Crocus Sativus L) 10 mg Capsule
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Aging Problems, Aging
Evaluating the Safety and Efficacy of Autologous Adipose Tissue-derived Mesenchymal Stem Cell Transplantation on Proinflammatory Cytokines and Anti-inflammatory Cytokines on Ageing-related Low-grade Inflammation Patients.
Single-group, open-label, phase I / II clinical trial: Evaluation of the safety of autologous adipose tissue-derived mesenchymal stem cell transplantation in inflammaging (Ageing-related low-grade inflammation) patients.
- Conditions
- Aging Problems, Aging, Chronic Inflammation
- Trial name
- NCT05827757
- Testing
- autologous adipose-derived mesenchymal stem cell transplantation
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- DNA International Hospital
Aging, Wrinkle Appearance
Anti-aging Efficacy Study on One Cosmetic Product Containing Mitopure
The aim of this study is to investigate the impact of a topical product on skin health and aging
- Trial name
- HCP-S1 (NCT07517887)
- Testing
- Skin care product
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Anti-Aging, Skin Aging
Evaluation of the Anti-aging Efficacy of Four Skin Health Products
The purpose of this study is to assess the anti-wrinkle and anti-aging efficacy of four different cosmetic products compared to an untreated control (split-face study design)
- Trial name
- NCT05473832
- Testing
- Day Cream cosmetic product compared to untreated side, Night cream cosmetic product compared to untreated side, Eye cream cosmetic product compared to untreated side
- Where
- Germany
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Anti-aging
Anti-aging Repairing Serum: Efficacy and Tolerability Study
The study aimed to evaluate the effectiveness and tolerability of a dermocosmetic serum containing hyaluronic acid, vitamin B5, madecassoside and La Roche-Posay Thermal Spring Water in reducing skin aging signs.
- Trial name
- NCT06059274
- Testing
- Topical serum
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International