Clinical trials: Anti-bacterial Agents
Acute Respiratory Tract Infection, Urinary Tract Infections
Routine Antibiotic Prescription Monitoring in Primary Care Physicians: A Nationwide Trial
Antibiotic resistance is an increasingly serious problem in Switzerland which is associated with the exposure and overall uptake of antibiotics in a population.
- Trial name
- NCT03379194
- Testing
- Antibiotic stewardship program
- Where
- Switzerland
- Volunteers
- 3,426 people
- Sponsor
- University Hospital, Basel, Switzerland
Surgical Site Infection, Anastomotic Leak
Oral Antibiotic Prophylaxis in Colorectal Surgery
The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral…
- Trial name
- ABCR (NCT03759886)
- Testing
- Paromomycin Sulfate Powder
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Leipzig
Infection
Safety and Outcomes Associated With Continuous Versus Intermittent Infusion Vancomycin
Evaluate the safety and outcomes associated between the two treatment modalities
- Trial name
- NCT04648696
- Testing
- Vancomycin CI, Vancomycin II
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Severe Sepsis, Septic Shock
Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock
Sepsis is a significant cause health care expenditure and carries an extremely high rate of morbidity and mortality if not treated appropriately.
- Conditions
- Severe Sepsis, Septic Shock, Bacteremia
- Trial name
- NCT01867905
- Where
- 7 sites in United States, Canada
- Volunteers
- 330 people
- Sponsor
- University of British Columbia
Septicemia, Bacterial Infections
Efficacy and Safety of Colistin Based Antibiotic Therapy
To evaluate the efficacy and safety of antibiotic combinations containing Colistin in the treatment of children with multidrug-resistant gram negative infections admitted in the pediatric surgery intensive care unit.
- Trial name
- NCT04764058
- Testing
- Tienam 500, Infusion
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Crohn's Disease
Efficacy and Safety of Anti-MAP Therapy in Adult Crohn's Disease
The investigators hypothesize that RHB-104 will have greater efficacy than placebo in Crohn's disease.
- Trial name
- MAPUS (NCT01951326)
- Testing
- RHB-104
- Where
- 103 sites in United States, Australia and 8 more
- Volunteers
- 331 people
- Sponsor
- RedHill Biopharma Limited
Febrile Neutropenia, Fever
Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients
This trial uses an interview and a survey to gather information from cancer patients about the onset of their fever and the administration of antibiotics.
- Trial name
- NCT03968328
- Testing
- Interview, Survey Administration
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- M.D. Anderson Cancer Center
Cystic Fibrosis
LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cystic Fibrosis Patients
In this trial, various factors that may influence the antibiotic concentrations measured in the sputum of cystic fibrosis patients are studied. A first factor is aerosol use.
- Trial name
- NCT02840136
- Testing
- Piperacillin-tazobactam combination product, Meropenem, Ceftazidime
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Ghent
Health-Related Quality-of-Life, Social Capital
Cocreating Action to Improve Rationality in the Health System
Despite widespread recognition of social, economic, or environmental health determinants, health action remains heavily dominated by individual-level solutions (e.g., medication, patient counselling, vaccination).
- Conditions
- Health-Related Quality-of-Life, Social Capital, Health Literacy, Community Based Participatory Research
- Trial name
- CAIR (NCT07237971)
- Testing
- Cocreation process
- Where
- 2 sites in Spain
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Pancreatic Diseases
Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics
This phase II/III trial compares the effect octreotide and the duration of antibiotic treatment has on outcomes in patients undergoing a Whipple procedure.
- Trial name
- NCT04329039
- Testing
- Somatostatin analog
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Mayo Clinic
Diarrhea, Antibiotic Associated Diarrhea
Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial
The aim of this study is to assess the effect of Lactobacillus reuteri DSM 17938 administration for the prevention of diarrhea and AAD in children.
- Trial name
- NCT02871908
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Medical University of Warsaw
Sinusitis
The Study of Nasonex® Compared With Placebo for the Relief of Symptoms Associated With Acute Bacterial Sinusitis When Used With Antibiotics (Study P04824AM3)
The purpose of this study is to evaluate the efficacy and safety of Nasonex® (mometasone furoate nasal spray), when used together with an antibiotic, for the relief of symptoms associated with acute bacterial sinusitis.
- Trial name
- NCT00423176
- Testing
- MFNS and antibiotic
- Volunteers
- 237 people
- Sponsor
- Organon and Co
Enterobacteriaceae Infections, Bloodstream Infection
Antibiotic Treatment Duration (7 vs 14 Days) Comparison in Blood Stream Infection Causes by Enterobacteriaceae
The antimicrobial crisis is a real problem. Infections produced by multiresistant bacteria are becoming more and more frequent, and available antimicrobial agents are usually scarce.
- Trial name
- SHORTEN (NCT02400268)
- Testing
- 7 days course of antibiotic treatment, 14 days course of antibiotic treatment
- Where
- 4 sites in Spain
- Volunteers
- 238 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Respiratory Tract Infections, Anti-Bacterial Agents
An Intervention to Reduce Inappropriate Prescriptions of Antibiotics for Respiratory Infections in General Practice
This study will explore the possible effect of a tailored educational intervention towards general practitioners, in order to improve antibiotic prescriptions for respiratory infections.
- Trial name
- NCT00272155
- Testing
- Educational intervention, Educational intervention program
- Where
- Norway
- Volunteers
- 118,621 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Febrile Neutropenia
Observational Non-Interventional Study Of Febrile Neutropenia Patients To Evaluate Antibacterial Therapeutical Options
The purpose of this study was to define and classify antibacterial agents used in Turkey for patients with febrile neutropenia.
- Trial name
- NCT00945555
- Testing
- Antibacterial agent for the treatment of febrile neutropenia
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 264 people
- Sponsor
- Pfizer
Community Acquired Pneumonia
Comparative Study of EDP-420 Versus Another Antibiotic in the Treatment of Community Acquired Pneumonia
This study will compare the efficacy, safety and tolerability of EDP-420 versus another oral antibiotic in the treatment of community acquired pneumonia
- Trial name
- NCT00270517
- Testing
- EDP-420 / Duration of Treatment - 3 days, Telithromycin / Duration of Treatment - 7 days
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Enanta Pharmaceuticals, Inc
Osteomyelitis of Lower Extremities, Osteomyelitis - Foot
Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot
The goal of this clinical trial is to compare different classes of oral antibiotics (beta-lactam and non-beta-lactam antibiotics) for the treatment of bone infections of the leg and foot.
- Conditions
- Osteomyelitis of Lower Extremities, Osteomyelitis - Foot, Osteomyelitis of the Foot
- Trial name
- OSTEO (NCT07266753)
- Testing
- Oral Beta-Lactam Antibiotic, Oral Non-Beta-Lactam Antibiotic
- Where
- 3 sites in Canada
- Volunteers
- 1,418 people
- Sponsor
- Michael Garron Hospital
Childhood Mortality
Mortality Reduction After Oral Azithromycin: Mortality Study
Our long-term goal is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood mortality.
- Trial name
- MORDORIMort (NCT02047981)
- Testing
- Azithromycin
- Where
- 6 sites in United States, Malawi and 3 more
- Volunteers
- 190,238 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Atopic Dermatitis (AD), Scabies
Secondary Bacterial Infections and Nasal Colonization in Scabies and Atopic Dermatitis
This prospective observational study will evaluate the microbiological profile of secondary bacterial infection and nasal colonization in participants with scabies or atopic dermatitis.
- Conditions
- Atopic Dermatitis (AD), Scabies, Impetigo
- Trial name
- NCT07813611
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Urinary Tract Infection, Antibiotic
The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.
Given the high burden of post-catheter removal UTIs, this study aims to evaluate Irrisept instillation as a non-antibiotic intervention to reduce infection rates.
- Conditions
- Urinary Tract Infection, Antibiotic, Catheter Infection
- Trial name
- NCT07239219
- Testing
- 0.05% Chlorhexidine Gluconate, Normal Saline
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
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