Clinical trials: Anti-inflammatory Agent
Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma
Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty
The type of anti-inflammatory medication used post selective laser trabeculoplasty (SLT) may have an impact on the intra-ocular pressure (IOP) lowering effect of SLT.
- Trial name
- NCT00485108
- Testing
- prednisolone 1%, ketorolac 0.5%, Artificial Tears (Methyl cellulose drops)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Queen's University
Gingivitis
Compare Anti-inflammatory Dentifrices
Plaque induced gingivitis
- Trial name
- NCT00762528
- Testing
- Triclosan/Copolymer/fluoride toothpaste, Sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Osteoarthritis, Knee
Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty
The purpose of this study is to identify whether corticosteroid use with anesthetics containing preservatives (parabens) reduces clinical effectiveness of the anti-inflammatory agent Up to 100 patients, both male and female…
- Trial name
- 5160373 (NCT03445611)
- Testing
- corticosteroid solution with lidocaine containing parabens., corticosteroid solution with lidocaine containing no paraben
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Periodontal Diseases, Gingivitis
The Effect of Vitamin D Supplementation on the Anti-inflammatory Response in Periodontal Diseases
A review of the literature revealed that while there are studies investigating the relationship between vitamin D and periodontal disease, there are no studies investigating the anti-inflammatory effect of vitamin D on…
- Conditions
- Periodontal Diseases, Gingivitis, Vitamin D Deficiency
- Trial name
- NCT07636733
- Testing
- Non-surgical periodontal treatment, Vitamin D administration, Oral Hygiene Education and Patient Motivation
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Periodontal Diseases, Periodontitis
The Role of Anti-inflammatory Cytokines and Antimicrobial Peptide LL-37 Biomarkers in the Treatment of Periodontal Disease.
Periodontal disease is an infectious pathology that consists of the destruction of the gums and supporting structures around the teeth. There are several mechanisms involved in this process.
- Trial name
- NCT04404335
- Testing
- Crevicular fluid analysis by using ELISA testing.
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Alzheimer Disease
Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)
The purpose of this trial is to test the ability of the non-steroidal anti-inflammatory medications naproxen and celecoxib to delay or prevent the onset of AD and age-related cognitive decline.
- Trial name
- NCT00007189
- Testing
- Naproxen Sodium (Aleve), Celecoxib (Celebrex)
- Where
- 6 sites in United States
- Volunteers
- 2,625 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Cutaneous Inflammation
Study on Anti-inflammatory Effects of Topical R115866 Gel
The purpose of this exploratory trial is to assess the anti-inflammatory effect(s) of topical R115866 in a model of UVB-induced inflammation and in a model of cutaneous irritation.
- Trial name
- NCT00719121
- Testing
- Talarozole, Differin™, 0.1% adapalene gel
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Pain, Hematuria
Diclofenac Suppository to Control Pain During Flexible Cystoscopy
Flexible cystoscopy has diagnostic as well as therapeutic role in many patients presenting in urology clinic with lower urinary tract symptoms (frequency, nocturia etc) and hematuria (blood in urine).
- Conditions
- Pain, Hematuria, Lower Urinary Tract Symptoms
- Trial name
- DUF (NCT01812928)
- Testing
- Diclofenac
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Functional Gastrointestinal Disorders
Intervention Study Focused on the Intestinal Microbiome to Evaluate the Impact of a Wild Thyme Extract (Thymus Serpyllum) Extract With Anti-inflammatory and Metabolic Properties Against Functional Gastrointestinal Disorders.
Functional gastrointestinal disorders (FGD), now known as disorders of gut-brain interactions (DGBI), are characterized by gastrointestinal symptoms linked to motility issues, visceral sensitivity, intestinal permeability, immune…
- Trial name
- InT-FGD (NCT06639126)
- Testing
- Wild thyme extract
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Gastrointestinal Hemorrhage, Ulcer
Gastroprotective Agent Compliance in Patients at Risk Suffering From a Gastrointestinal(GI) Ulcer
The purpose of this study is to assess gastroprotective agent compliance in patients at risk suffering from a gastrointestinal bleeding ulcer or a symptomatic ulcer with NSAID.
- Trial name
- NCT01215058
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Unrecognized Condition
Deep Diaphragmatic Breathing: Neurobiological and Anti-inflammatory Effects
The exposure to acute and\or chronic stress can produce an activation of sympathetic nervous system (SNS), leading to an increased level of cortisol and pro-inflammatory cytokines.
- Trial name
- NCT04102813
- Testing
- Functional Therapy
- Where
- Italy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Cardiovascular Disease
The Effect of Seaweed Derived Polyphenols on Inflammation and Oxidative Stress in Vivo - The SWAFAX Study
Cardiovascular disease (CVD) is currently the leading cause of death worldwide. Epidemiologic studies have shown a diet rich in plant food protects against chronic degenerative diseases especially cardiovascular disease.
- Trial name
- SWAFAX (NCT02295878)
- Testing
- Treatment capsule containing seaweed extract (treatment)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Tooth, Impacted, Trismus
Efficacy of Chronoterapy in Oral Surgery
Lower third molar extraction is one of the most common treatments in oral surgery practice. It is a treatment with inherent complications such as postoperative pain, swelling or trismus.
- Conditions
- Tooth, Impacted, Trismus, Pain, Inflammatory Response
- Trial name
- ECOS (NCT05126264)
- Testing
- Ibuprofen 400 mg
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Gingivitis, Dental Plaque
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction.
- Trial name
- NCT04723732
- Testing
- Myrrh mouthwash, Chlorhexidine mouthwash, Normal saline
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University