Clinical trials: Antibiotic Allergy
Penicillin Allergy
Geisinger Antibiotic Allergy Pilot Program: Assess and Address
This is a prospective non-inferiority study to evaluate penicillin allergy history in patients with reported penicillin allergy, who require penicillin or penicillin-derivative antibiotic during inpatient admission using a…
- Trial name
- GAAP (NCT05464615)
- Testing
- Amoxicillin
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Geisinger Clinic
Community Acquired Pneumonia (CAP)
Local Antibiotic Delivery for Community Acquired Pneumonia
A randomized, double-blinded clinical pilot study to assess whether addition of inhaled levofloxacin 240 mg twice daily for three days leads to improved or worsened physiological status in CAP patients with and without…
- Trial name
- LANDCAP-1 (NCT06859450)
- Testing
- Levofloxacin
- Volunteers
- 36 people
- Sponsor
- Copenhagen Respiratory Research
Allergy
Negative Predictive Value and NIC of Beta-Lactam Antibiotics.
The researchers are trying to evaluate how much medication is required for allergy skin testing and to determine the likelihood that patients with a negative test truly don't have an allergy to the tested drug of skin testing to…
- Trial name
- NCT04126096
- Testing
- Skin Testing beta-lactams
- Where
- 2 sites in United States
- Volunteers
- 747 people
- Sponsor
- Mayo Clinic
Infectious Disease
Clinical Decision Support Tools for Antibiotic Prescribing
The goal of this study is to assess the utility of a data visualization tool for providers' understanding patients' past microbiological culture sensitivities.
- Trial name
- NCT03580603
- Testing
- Visualization tool
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetic Foot
Bacteriological Study of Diabetic Foot and Antibiotic Sensitivity Pattern in Eastern India
The pattern of organism causing diabetic foot infection are presumed to vary from location to location depending on the antibiotic prescription practice, geographical locations, environmental variations and therapeutic…
- Trial name
- NCT01351701
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Sun Valley Hospital, Guwahati
Asthma, Lung Diseases
Antibiotics in Infancy--Risk Factor for Childhood Asthma
To examine possible relationships between antibiotic use, as determined by prescriptions filled, and asthma in children ages 6 to 7.
- Trial name
- NCT00037726
- Sponsor
- Augusta University
Drug Allergy, Antibiotic Allergy
Improved Basophil Activation Test (BAT) in the Diagnostics of Drug Allergy
Current study evaluates the use of the improved Basophil Activation Test (BAT) in the diagnostics of IgE-mediated allergy to antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs).
- Conditions
- Drug Allergy, Antibiotic Allergy, NSAID-Induced Anaphylactoid Reaction
- Trial name
- NCT03164044
- Where
- Belarus
- Volunteers
- 45 people
- Sponsor
- The Republican Research and Practical Center for Epidemiology and Microbiology
Chronic Periodontitis
STUDY ON THE EFFECTS OF PERIODONTAL TREATMENT ALONG WITH THE USE OF ANTIBIOTICS OVER HIGH SENSITIVE C-REACTIVE PROTEIN. RANDOMIZED CONTROLLED CLINICAL TRIAL.
Human periodontitis is a group of highly prevalent oral inflammatory diseases and infections with relatively easy treatment and preventive features.
- Trial name
- NCT01906450
- Testing
- Scaling and root planing plus Azithromycin
- Where
- Colombia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Pulmonary Sarcoidosis, Lung Function
Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis
Sarcoidosis is a granulomatous disease for which the molecular and immunologic association with mycobacteria continues to strengthen.
- Trial name
- CLEAR Lung (NCT01169038)
- Testing
- levaquin; ethambutol; rifampin and azithromycin.
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Vanderbilt University
Beta-Lactams Allergy, Hypersensitivity
Genomic Study of Genetic Polymorphisms Involved in Immediate Allergic Reactions to Beta-lactam Antibiotics
Beta-lactam antibiotics include penicillin and cephalosporins and are among the most prescribed antibiotics. This category of drugs is the most involved in immediate allergic manifestations with 2% reactions in treated subjects…
- Trial name
- PANGENOMIC-BL (NCT02895646)
- Testing
- Collection of blood sample
- Volunteers
- 2,356 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Atopic Dermatitis
Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema
The purpose of this study is to determine the effect of topical pimecrolimus on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with eczema.
- Trial name
- NCT00946478
- Testing
- Pimecrolimus, Vehicle cream
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Antibiotic Sensitivity Testing and Genotypic Caharacterization of Ecoli
Phenotypic and Genotypic Characterization of Escherichia Coli
Collection of urine samples Cultivation Antibiotic sensitivity test PCR
- Trial name
- NCT06462261
- Volunteers
- 100 people
- Sponsor
- Sohag University
Postoperative Complications, Antibiotic Reaction
Complications After Lower Third Molar Surgery
Surgical removal of impacted mandibular wisdom teeth is a frequent intervention, usually accompanied by unpleasant sequelae (pain, swelling and trismus) in the postoperative period, sometimes even with possibly serious…
- Conditions
- Postoperative Complications, Antibiotic Reaction, Antibiotic Side Effect, Antibiotic Resistant Infection
- Trial name
- NCT05027893
- Testing
- Moxifloxacin 400 mg Oral Tablet, Cefixime 400 mg Oral Tablet
- Where
- Serbia
- Volunteers
- 157 people
- Sponsor
- University of Novi Sad
Orthopedic Surgery
Biofilm Formation and Antibiotic Sensitivity Patterns
Detection of bacteria that form biofilm and its sensitivity to antibiotics in patients with surgical site infection after orthopedic surgery.
- Trial name
- NCT05181163
- Testing
- swab
- Volunteers
- 100 people
- Sponsor
- Sohag University
Atopic Dermatitis (AD), Scabies
Secondary Bacterial Infections and Nasal Colonization in Scabies and Atopic Dermatitis
This prospective observational study will evaluate the microbiological profile of secondary bacterial infection and nasal colonization in participants with scabies or atopic dermatitis.
- Conditions
- Atopic Dermatitis (AD), Scabies, Impetigo
- Trial name
- NCT07813611
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Atopic Dermatitis
Observer-Blinded Dose Escalating, Single Dose to Study Safety and Antimicrobial Efficacy of Gel vs. Placebo
A Randomized, Observer-Blinded, Vehicle Controlled, Single Dose, Dose Escalating, Single Application Within-patient Bilateral Comparison. The goal is to determine the safety and tolerability of DBI-001 Gel vs.
- Trial name
- NCT04192513
- Testing
- J. lividum
- Where
- Dominican Republic
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- DermBiont, Inc.
Severe Atopic Dermatitis
Efficacy of Combining Topical Antibiotic/Steroid/Moisturizer Therapy Compared to Active Comparator in Atopic Dermatitis.
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease that occurs most commonly during early infancy and childhood.
- Trial name
- NCT03052348
- Testing
- Polyethylene glycol hexadecyl ether & Betamethasone valerate cream 0.1%, Fusidic acid, polyethylene glycol hexadecyl ether & Betamethasone valerate cream 0.1%
- Where
- 3 sites in South Africa
- Volunteers
- 78 people
- Sponsor
- Red Cross War Memorial Childrens Hospital
Obesity, Insulin Resistance
The Importance of the Gut Microbiota in Body Weight Control and Insulin Sensitivity
BACKGROUND: The relation between gut microbiota and obesity originates from animal studies, showing that the change of gut microbiota can induce changes in both insulin resistance and body composition.
- Trial name
- ANTIBIOTICS (NCT02241421)
- Testing
- Amoxicillin, Vancomycin
- Where
- Netherlands
- Volunteers
- 57 people
- Sponsor
- Maastricht University Medical Center
Drug Allergy
Multiple Drug Hypersensitivity Syndrome
Background: Multiple drug hypersensitivity syndrome (MDH) is defined as confirmed drug hypersensitivity reactions (DHRs) to at least 2 chemically and pharmacologically unrelated drugs.
- Trial name
- MDH (NCT03784482)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Nosocomial Infection in Neonatal Intensive Care Unit
Bacteriological Profile and Antibiotic Sensitivity in Neonatal Intensive Care Unit at Assuit University Children Hospital
The study aims to assess the bacteriological profile and antibiotic sensitivity in NICU of pediatric hospital of assuit university.
- Trial name
- NCT06891768
- Testing
- Blood culture
- Volunteers
- 134 people
- Sponsor
- Assiut University