Clinical trials: Antibiotic Prescription
Urinary Tract Infections
Reducing Antibiotic Prescriptions for Urinary Tract Infection in Long-Term Care Facilities
This cluster randomized controlled study evaluates the effect of a tailored observation, reflection and communication tool on used by long-term care facility staff on antibiotic prescription for urinary tract infection in…
- Trial name
- NCT03715062
- Testing
- Dialogue tool
- Where
- Denmark
- Volunteers
- 1,491 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Fracture Femur, Fracture Tibia
Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail
Long-bone fractures, particularly of femur and tibia, are common following fall injury and road traffic accidents.1,2 The standard treatment is "intramedullary nailing," where a metal rod is inserted into the center of the bone…
- Conditions
- Fracture Femur, Fracture Tibia, Surgical Site Infection (SSI), Antibiotic
- Trial name
- NCT07554079
- Testing
- Short Course Antibiotics, Standard Course Antibiotics
- Where
- Nepal
- Volunteers
- 56 people
- Sponsor
- Kathmandu University School of Medical Sciences
Acute Respiratory Tract Infection, Urinary Tract Infections
Routine Antibiotic Prescription Monitoring in Primary Care Physicians: A Nationwide Trial
Antibiotic resistance is an increasingly serious problem in Switzerland which is associated with the exposure and overall uptake of antibiotics in a population.
- Trial name
- NCT03379194
- Testing
- Antibiotic stewardship program
- Where
- Switzerland
- Volunteers
- 3,426 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Upper Respiratory Tract Infections
Trial of Post-Dated Delayed Antibiotic Prescriptions
Delayed prescriptions have been shown to lower antibiotic use for upper respiratory tract infections (which are mostly viral). This trial will test the hypothesis that if the clinician post-dates the delayed prescription by 2…
- Trial name
- NCT02732847
- Testing
- A delayed prescription dated 2 days after clinical office visit, Usual Dated
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- Memorial University of Newfoundland
Acute Febrile Illness
Electronic Algorithms Based on Host Biomarkers to Manage Febrile Children
Health professionals in developing countries have limited ability to identify children at risk of dying and those in need of antibiotics.
- Trial name
- e-POCT (NCT02225769)
- Testing
- Management of febrile children using e-POCT, Management of febrile children using ALMANACH
- Where
- Tanzania
- Volunteers
- 3,192 people
- Sponsor
- Swiss Tropical & Public Health Institute
Pneumonia
Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected Pneumonia
Pneumonia is a common pathology with significant morbidity and mortality. It is recommended in his diagnostic approach to perform either a chest X-ray or a pleuropulmonary ultrasound.
- Trial name
- PRE-EPPA (NCT07703852)
- Testing
- Pleuropulmonary ultrasound performed by the investigator for patient with suspicion od Pneumonia
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Antibiotic Prescription
Prescription Pattern and Awareness About Antibiotic Prophylaxis and Resistance
To assess the knowledge of Pediatric dentists regarding the prescription of antibiotics, antibiotic prophylaxis and antibiotic resistance
- Trial name
- NCT04031443
- Where
- Egypt
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sepsis, Septic Shock
A STUDY BEFORE/AFTER THE IMPLEMENTATION OF AN ANTI-INFECTIOUS PRESCRIPTION AID
Anti-infective strategy is a major public health problem. This is a before-and-after study of an anti-infectious prescription tool with a comparison of mortality at 30 days (then 3 and 6 months) between the two inclusion phases…
- Trial name
- NCT05140213
- Testing
- Anti-infectious prescription support tool
- Where
- France
- Volunteers
- 371 people
- Sponsor
- University Hospital, Montpellier
Antibiotic Prescriptions, Infection
Optimizing Management and Medication of Febrile Children in Out-of-hours Primary Care: CHILI Cluster RCT
The CHILI cluster randomised controlled trial (RCT) will investigate whether the use of an interactive information booklet during consultations for febrile children at General Practice (GP) out-of-hours centres can reduce the…
- Trial name
- CHILI (NCT02594553)
- Testing
- GP-parent information-exchange tool
- Where
- Netherlands
- Volunteers
- 1,262 people
- Sponsor
- Maastricht University Medical Center
Antibiotic Side Effect
Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District
Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic…
- Trial name
- NCT04127682
- Testing
- Antibiotic KAP questionnaire
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Assiut University
Children
Children With Fever and Respiratory Symptoms at Out-of-hours Services in Norway
Viral self-limiting infections in respiratory organs among children are common in primary care. Serious infections have low prevalence and are challenging to distinguish from self-limiting infections.
- Trial name
- NCT02496559
- Testing
- Pre-consultation CRP
- Volunteers
- 401 people
- Sponsor
- NORCE Norwegian Research Centre AS
Respiratory Tract Infection
Antibiotics in Patients With Acute Respiratory Tract Infection With Procalcitonin as Parameter
Antibiotics in patients with acute respiratory tract infections in primary care in consideration of procalcitonin as additive parameter.
- Trial name
- NCT00688610
- Testing
- laboratory value procalcitonin
- Where
- Germany
- Volunteers
- 571 people
- Sponsor
- Hannover Medical School
Febrile Neutropenia
Impact of Computerized Decision Support for ANTIBIOtic Prescription in Cancer Patients With Febrile NEutropenia in the Emergency Department on Treatment Failure.
Treatment of patients with febrile neutropenia (FN) attending Emergency Departments (EDs) relies on rapid antibiotic initiation in order to control a presumed infection.
- Trial name
- ANTIBIONEED (NCT05206006)
- Testing
- routine care, Computerized Decision support app (CDSA)
- Volunteers
- 540 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prescribing, Off-Label
CMO Letter to Reduce Unnecessary Antibiotic Prescribing March 2018
This trial aims to reduce unnecessary prescription of antibiotics by general practitioners (GPs) in England. Unnecessary prescriptions are defined as those that do not improve patient health outcomes.
- Trial name
- NCT03582072
- Testing
- letter from the CMO
- Where
- United Kingdom
- Volunteers
- 4,796 people
- Sponsor
- Public Health England
Hospital Infection, Standardized Antibiotic Prescribing Ratio (SAR)
InPART RX - Epicenters
InPART Rx is a collaborative research study to measure the impact of a planned quality improvement initiative to reduce unnecessary antibiotic prescribing by the Hospital Medicine Service through a process of receiving…
- Trial name
- InPART RX (NCT07368660)
- Testing
- Messaging Hospitalists, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Emory University
Modality of Discharge Instructions
Effect of Modality on Discharge Instruction in Patients Receiving Outpatient Antibiotic Prescriptions From the Emergency Department
Outpatient antibiotics are frequently prescribed from the emergency department, and limited health literacy may impact compliance with recommended treatments.
- Trial name
- NCT01775969
- Testing
- Text Message, Voicemail
- Where
- United States
- Volunteers
- 2,874 people
- Sponsor
- Hennepin Healthcare Research Institute
Fever
The Impact of C-reactive Protein Testing
PRIMARY OBJECTIVE To assess the impact of C-reactive protein (CRP) Point-of-care (POC) testing on health care worker prescribing behaviour in patients presenting to primary healthcare centres with an acute fever or recent history…
- Trial name
- NCT02758821
- Testing
- No CRP will be measured onsite, CRP cut-off of 20mg/L., CRP cut-off of 40mg/L.
- Where
- Thailand
- Volunteers
- 2,410 people
- Sponsor
- University of Oxford
Upper Respiratory Tract Infections, Urinary Tract Infections
Routine Prescription Feedback and Peer Comparison to Lower Antibiotic Prescriptions in Primary Care
To evaluate the effect of a continuous postal and web-based feedback and peer comparison system of individual antibiotic prescription rates on the prescription behaviour of primary care physicians in Switzerland.
- Trial name
- NCT01773824
- Testing
- Antibiotic prescription feedback, No Feedback
- Where
- Switzerland
- Volunteers
- 2,900 people
- Sponsor
- University Hospital, Basel, Switzerland
Pseudomonas
Impact of Modifications to the Rendering of the Antibiogram on the Prescriptions of Meropenem in Pseudomonas Bacteremia
Modification of the rendering of the antibiogram at the Strasbourg University Hospital in November 2019 with the appearance of the concept of "standard dose" or "high dose" sensitivity.
- Trial name
- Mero-Pyo (NCT06113107)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Non-Prescription Drug Misuse, Antibiotic Use
Intervention on Non-prescription Antibiotic Use Among the Public
The purpose of this study is to test the effectiveness of health education int led by community health workers for non-prescription antibiotic use among the public.
- Trial name
- NCT06317415
- Testing
- WeChat-based health education on antibiotic use, Regular public health education
- Where
- China
- Volunteers
- 1,550 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology