Clinical trials: Antibiotic Resistance Genes
Polio
Environmental Surveillance (ES) for Polio and AMR Using the TaqMan Array Card
This study will be used to develop a tool to streamline poliovirus environmental surveillance for the polio endgame and to provide a tool for detecting polio in places where there is no capacity to carry out the gold standard…
- Trial name
- NCT03818477
- Where
- Bangladesh
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Infectious Disease
Effects of Phenoximethylpenicillin, Amoxicillin and Amoxicillin-clavulanic Acid on the Gut Microbiota
The overall aim of the project is to fill an important knowledge gap on the ecological effects of selected antibiotics. The results will be used to guide treatment decisions for common infections to as much as possible reduce the…
- Trial name
- EPAAC (NCT04084106)
- Testing
- Phenoxymethylpenicillin, Amoxicillin, Amoxicillin-clavulanic acid
- Where
- Sweden
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Microbiome
Effect of a Probiotic or Postbiotic on Gut Microbiome During Antibiotic Treatment
This study assesses the effects of a probiotic or postbiotic on gut microbiome during antibiotic treatment.
- Trial name
- POTATO-2 (NCT07594860)
- Testing
- Probiotic, Postbiotic
- Where
- Greece
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Periodontal Disease, Periodontitis
Antibiotic Resistance Genes in Periodontitis
Antimicrobial resistance (AMR) is a major global public health concern, and the oral microbiome may serve as an important reservoir of antibiotic resistance genes (ARGs).
- Conditions
- Periodontal Disease, Periodontitis, Antibiotic Resistance Genes
- Trial name
- NCT07887204
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
ISOLATION OF KLEB. by Culture on macConkey Agar, Antibiotic Sensitivity Testing of Different Antibiotics According to Clsi 25
Effect of Ceftazidime-Avibactam on Carbapenemase-Producing Klebsiella Pneumoniae
Specimen Collection : Clinical specimens included blood, urine, bronchoalveolar lavage fluid, wound, peritoneal fluid, and tracheal aspirate obtained from patients with suspected bacterial infections collected in dry sterile…
- Conditions
- ISOLATION OF KLEB. by Culture on macConkey Agar, Antibiotic Sensitivity Testing of Different Antibiotics According to Clsi 25, Effect of Ceftazidime-Avibactam on Carbapenemase-Producing Klebsiella Pneumoniae, Detection of Resistance Gene in Isolates Using Conventional Pcr
- Trial name
- NCT07369518
- Testing
- . - Genotypic detection of carbapenemase genes by conventional PCR.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Antimicrobial Resistance (AMR), Oral Microbiota
Salivary Microbiota and Antimicrobial Resistance in Relation to Chlorhexidine Use
This study evaluated the ecological effects of 0.06% chlorhexidine toothpaste on the salivary microbiota of healthy individuals, focusing on taxonomic composition, functional shifts, and prevalence of predicted antimicrobial…
- Conditions
- Antimicrobial Resistance (AMR), Oral Microbiota, Oral Microbiome Health, Chlorhexidine
- Trial name
- SMARCH (NCT07570927)
- Testing
- 0.06% Chlorhexidine Digluconate Toothpaste
- Where
- 2 sites in Czechia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Peri-implant Mucositis, Oral Bacterial Infection
Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments
The aim of this study is to determine the relative abundances of the different bacterial phyla and families in the microbiota present on the surface of PEEK implant-supported provisional abutments compared to titanium…
- Conditions
- Peri-implant Mucositis, Oral Bacterial Infection, Bacterial Resistance
- Trial name
- NCT03998865
- Testing
- Provisional abutment material
- Where
- Chile
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Michael Wendler Ernst
Diarrhea Travelers, Antibiotic Resistant Infection
Bismuth Subsalicylate's Role in the Prevention of Travelers' Diarrhea
The purpose of this study is to determine if the use of prophylactic bismuth subsalicylate (BSS) has an effect on the acquisition of travelers' diarrhea (TD) or antimicrobial resistance (AMR) genes in fecal samples among…
- Trial name
- NCT03535272
- Testing
- Bismuth subsalicylate
- Where
- United States
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Intensive Care Unit
Intestinal Microbiota and Their Antibiotic Resistance Genes of ICU Health Care Workers
In this study, metagenomic sequencing (10G) results of stool samples from health care workers in ICU and non-medical professionals were compared to observe whether there are significant differences in community diversity…
- Trial name
- NCT06524765
- Testing
- Living conditions
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology