Clinical trials: Antibiotic Usage
Antibiotic Side Effect, Antibiotic Resistant Infection
Antibiotic Use and Resistance KAP Among Dental Interns
The study is designed as a cross-sectional online-based questionnaire, and it will be distributed among dental interns. Assess the following among dental interns (1) The knowledge, attitude, and practices (KAP) towards…
- Trial name
- NCT06383637
- Volunteers
- 343 people
- Sponsor
- Cairo University
Infection Post Op, Hysterectomy
Does Additional Use of Preoperative Azithromycin Decrease Posthysterectomy Infections
During hysterectomy bacteria may enter into the peritoneal cavity through vaginal opening and contaminate the healing tissues. The risk for deep infection after hysterectomy is about 5%.
- Conditions
- Infection Post Op, Hysterectomy, Antibiotics, Prophylactic
- Trial name
- NCT05337566
- Testing
- Azithromycin Pill + Cefuroxime
- Where
- 6 sites in Finland
- Volunteers
- 2,278 people
- Sponsor
- Helsinki University Central Hospital
End Stage Renal Failure on Dialysis, Infection, Bacterial
Antimicrobial Use and Stewardship in an Outpatient Hemodialysis Unit
This quality improvement study will assess the antimicrobial use and prescribing practices of hospital and community prescribers for the ambulatory hemodialysis (HD) population in an urban academic outpatient HD unit in Ontario.
- Trial name
- NCT03172039
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University Health Network, Toronto
Gram Positive Bacterial Infection
Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics
This is a research study designed to look at the pharmacokinetics (distribution, breakdown, and removal) and tolerability of a single dose of daptomycin in patients aged 3 months to 24 months who have proven or suspected…
- Trial name
- NCT01019395
- Testing
- Daptomycin
- Where
- 8 sites in United States
- Volunteers
- 23 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Chronic Sinus Infection
The Use of Prophylactic Antibiotics in Endoscopy Sinus Surgery for Chronic Rhinosinusitis With or Without Polyp
This is a randomized, double-blind clinical trial on the prophylactic use of antibiotics in postoperative endoscopic sinus vs placebo surgery.
- Trial name
- NCT03809312
- Testing
- Amoxicillin / Clavulanic acid 875mg / 125mg
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- CHU de Quebec-Universite Laval
Urinary Tract Infection(UTI), Antimicrobial Stewardship
Diagnostic Stewardship Intervention to Reduce Inappropriate Antibiotic Use for Urinary Tract Infections in Primary Care
Urine culture is the most common microbiological test in the outpatient setting in the United States. Unfortunately, contamination during collection is prevalent and undermines test accuracy, leading to incorrect diagnosis…
- Conditions
- Urinary Tract Infection(UTI), Antimicrobial Stewardship, Primary Care
- Trial name
- NCT07246837
- Testing
- MSCC Educational Tool
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Baylor College of Medicine
Bacteremia, Antimicrobial Stewardship
Knowledge Attitude and Practice Regarding Bloodstream Bacterial Infections and Antibiotics Usage Among Doctors.
This study is designed to use a questionnaire to assess doctors' knowledge, attitudes, and practices regarding bloodstream bacterial infections and antibiotic use in Tawam and Al Ain tertiary Hospitals (both hospitals have the…
- Conditions
- Bacteremia, Antimicrobial Stewardship, Antibiotic Use, Antibiotic Abuse
- Trial name
- NCT06605677
- Testing
- Questionnaire
- Where
- United Arab Emirates
- Volunteers
- 100 people
- Sponsor
- Abu Dhabi Health Services Company
Gastroenteritis
Impact of the Introduction of a Gastro-intestinal Panel by Polymerase Chain Reaction (PCR).
Evaluation of the impact of the introduction of multiplex PCR panels on the clinical management of patients with gastroenteritis at the University Hospital of Lausanne, Switzerland.
- Trial name
- NCT03551340
- Testing
- Gastro-intestinal panel by PCR
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- University of Lausanne Hospitals
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Infection, Antimicrobial Stewardship
Quality Improvement Intervention for a Safe Antimicrobial Use Reduction in Critically Ill Patients
The goal of this clinical trial is to learn if an educational intervention with audit and feedback on physicians and health care professionals who participate in antimicrobial treatment decisions can reduce the use of…
- Conditions
- Infection, Antimicrobial Stewardship, Critically Ill Intensive Care Unit Patients
- Trial name
- SAFE-REDUCE (NCT07093450)
- Testing
- Educational Quality Improvement Intervention
- Where
- 9 sites in Brazil
- Volunteers
- 9,000 people
- Sponsor
- Hospital Sirio-Libanes
Chronic Periodontitis
STUDY ON THE EFFECTS OF PERIODONTAL TREATMENT ALONG WITH THE USE OF ANTIBIOTICS OVER HIGH SENSITIVE C-REACTIVE PROTEIN. RANDOMIZED CONTROLLED CLINICAL TRIAL.
Human periodontitis is a group of highly prevalent oral inflammatory diseases and infections with relatively easy treatment and preventive features.
- Trial name
- NCT01906450
- Testing
- Scaling and root planing plus Azithromycin
- Where
- Colombia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Antibacterial Agents, Ambulatory Care
Improving Antibiotic Use for ARIs in Urgent Care Clinics
Many clinicians prescribe antibiotics for patients with acute respiratory infections even when antibiotics will not benefit the patient because the infection is due to a virus.
- Trial name
- NCT06144242
- Testing
- Feedback on RTD metric
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniel Livorsi
Osteosynthesis, Infection Prevention
Use of a Taurolidine Containing Antimicrobial Wash to Reduce Prosthetic Device Infection After Trauma Surgery
A taurolidine-based antimicrobial solution, was evaluated for its safety and efficacy in preventing infections associated with prosthetic materials, such as joint replacements, plates, nails, and screws.
- Trial name
- Prosafeti (NCT06919770)
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- University of Kiel
Cellulitis
The Effect of Dermatology and Teledermatology Consultations on Length of Hospital Admission, 30 Day Readmission Rate, and Antibiotic Use in Patients Presenting With Cellulitis vs Pseudocellulitis in an Academic Inpatient Setting
The effect of teledermatology on length of hospital admission, length of stay, 30 day readmission rate, and antibiotic use in patients presenting with cellulitis vs pseudocellulitis in an academic emergency department setting.
- Trial name
- NCT03034694
- Testing
- teledermatology consult, Routine Care
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Recurrent Urinary Tract Infection
Effect of Nanotechnology Structured Water Magnalife for the Prevention of Recurrent Urinary Tract Infections.
This study investigates nanotechnology structured water magnalife in urology and to test its effects against lower urinary tract infections (UTI) in females.
- Trial name
- NCT04306731
- Testing
- Nanotechnology Structured water Magnalife, Trimethoprim, Ordinary bottled drinking water
- Where
- Iraq
- Volunteers
- 437 people
- Sponsor
- University of Sulaimani
Communicable Diseases
Computerized Antibiotic Stewardship Study
Prescribing antibiotics frequently poses problems in practice, since patients don't always receive the right dosage of the right antibiotic for the right period of time.
- Trial name
- COMPASS (NCT03120975)
- Testing
- Computerized decision support and audit & feedback, Audit & Feedback, Standard antibiotic stewardship
- Where
- 3 sites in Switzerland
- Volunteers
- 16,176 people
- Sponsor
- Benedikt Huttner
Skin Diseases, Infectious
Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management
The purpose of this study is to determine if antibiotics are required in the management of skin abscess following incision and drainage.
- Trial name
- NCT00679302
- Testing
- Trimethoprim-sulfamethoxazole
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- St. Louis University
Respiratory Disease, Acute Respiratory Infection
Dialogue Around Respiratory Illness Treatment
Unwarranted use of antibiotics for pediatric acute respiratory tract infections (ARTIs) and use of second-line, broad spectrum antibiotics for bacterial ARTIs has contributed to the rapid development of resistance in many strains…
- Conditions
- Respiratory Disease, Acute Respiratory Infection, Respiratory Infection, Upper Respiratory Infection
- Trial name
- DART (NCT02943551)
- Testing
- Online Tutorial, Webinars, Booster Sessions
- Where
- 20 sites in United States
- Volunteers
- 2,728 people
- Sponsor
- Seattle Children's Hospital
Hepatocellular Carcinoma
Study of ThermoDox With Standardized Radiofrequency Ablation (RFA) for Treatment of Hepatocellular Carcinoma (HCC)
The purpose of this study is to determine whether ThermoDox, a thermally sensitive liposomal doxorubicin, is effective in the treatment of non-resectable hepatocellular carcinoma when used in conjunction with standardized…
- Trial name
- OPTIMA (NCT02112656)
- Testing
- ThermoDox, Dummy infusion
- Where
- 61 sites in United States, Canada and 12 more
- Volunteers
- 554 people
- Sponsor
- Imunon
Urinary Tract Infections, UTI
Cranberry and Quillaja on Symptoms of Uncomplicated UTI
This study will investigate the effects of cranberry and quillaja capsules on symptoms of uncomplicated urinary tract infections.
- Conditions
- Urinary Tract Infections, UTI, UTI - Lower Urinary Tract Infection
- Trial name
- NCT04496726
- Testing
- Pacran and Sapnov P quillaja
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's