Clinical trials: Antibiotic Usage
Pneumonia
Anaerobic Antibiotic Usage for Pneumonia in the Medical Intensive Care Unit
Observation of prescription usage of anaerobic antibiotics for patients admitted to the ICU with pneumonia.
- Trial name
- NCT03046082
- Testing
- Antibiotics
- Volunteers
- 192 people
- Sponsor
- Henry Ford Health System
Infection
Antimicrobials Stewardship by Pharmacist
To study the outcome of antibiotics stewardship
- Trial name
- NCT02768454
- Testing
- medical review of controlled broad-spectrum antibiotics
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Healing Wound
Adjunctive Use of an Antibacterial Honey Dressing for Palatal Wound Healing After Harvesting a Free Gingival Graft
This case-control study will afford a more understanding of the clinically benefits that the antibacterial honey dressing material has in palatal wound healing and the subsequent effects in post-operative morbidity.
- Trial name
- NCT04269694
- Testing
- Medihoney dressing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Infection With Multi-drug Resistant Organisms
FMT for Multidrug Resistant Organism Reversal
This proposed protocol involves the use of the fecal microbiota transplantation (FMT) to suppress or reverse colonization with multidrug resistant organisms (MDRO) in subjects with recurrent MDRO infections due to organisms of…
- Trial name
- NCT02312986
- Testing
- Fecal microbiota transplantation (FMT)
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Antibacterial Agents, Ambulatory Care
Improving Antibiotic Use for ARIs in Urgent Care Clinics
Many clinicians prescribe antibiotics for patients with acute respiratory infections even when antibiotics will not benefit the patient because the infection is due to a virus.
- Trial name
- NCT06144242
- Testing
- Feedback on RTD metric
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniel Livorsi
Severe Sepsis, Septic Shock
Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections
In this study the investigators aim to test if C-reactive protein (CRP)or procalcitonin(PCT) - guided strategy allows to reduce the antibiotic use in patients wiht severe sepsis and septic shock.
- Trial name
- NCT00934011
- Testing
- C-reactive protein guided antibiotic therapy, Procalcitonin guided antibiotic therapy
- Where
- Brazil
- Volunteers
- 94 people
- Sponsor
- Federal University of Minas Gerais
Hypospadias
Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair
The purpose of this study is to evaluate the efficacy of prophylactic antibiotics following distal or mid-shaft hypospadias repair in influencing the rate of postoperative urinary tract infection and complications.
- Trial name
- NCT02593903
- Testing
- Septra
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Medical College of Wisconsin
Catheter-Associated Urinary Tract Infections (CAUTIs)
Evaluate of the Use of Uromune as a Potential Non-antibiotic Prophylactic Strategy for Catheter-associated Urinary Tract Infection in Patients With Long-term Catheterization.
A self-controlled pilot study to evaluate the use of oral bacterial immunotherapy for prevention of catheter-associated urinary tract infection.
- Trial name
- NCT07869992
- Testing
- Uromune
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Infections Joint Prosthetic, Overweight or Obesity
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients
To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk…
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA
- Trial name
- NCT04297592
- Testing
- Cephalexin, Doxycycline, Cefadroxil
- Where
- 2 sites in United States
- Volunteers
- 4,618 people
- Sponsor
- Mayo Clinic
Diarrhea
Impact of Bismuth Subsalicylate on Antimicrobial Use Among Adult Diarrhea Outpatients--Pakistan
The purpose of this study is to learn whether bismuth subsalicylate can reduce use of antibiotics among adults with diarrhea in Pakistan.
- Trial name
- NCT02047162
- Testing
- Bismuth subsalicylate
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Respiratory Syncytial Virus Infections, Antibiotic Stewardship in Community Hospitals
RSV Antibiotic Drivers And Resource-use
This study retrospectively evaluated the clinical, laboratory, and radiologic factors that influence the decision to prescribe antibiotics in children under 2 years of age hospitalized with RSV-positive acute lower respiratory…
- Trial name
- RADAR (NCT06977971)
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Multi-antibiotic Resistance
Use of New Antibiotics in Sweden
Antibiotic resistance is a growing global health problem of great concern, especially multidrug-resistant Gram-negative bacteria. In recent years some new antibiotics targeting these bacteria have been developed.
- Trial name
- NCT05048693
- Where
- 7 sites in Sweden
- Volunteers
- 41 people
- Sponsor
- Uppsala University
Urinary Tract Infections, Sepsis
Use of Antibiotic Based Irrigation for Ureteroscopic Treatment of Urolithiasis
The purpose of the study is to investigate whether the use of gentamicin-based irrigation fluid during ureteroscopy decreases the risk of UTIs and other post-operative infections after surgery.
- Trial name
- NCT06007352
- Testing
- Gentamicin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Periodontal Diseases, Oral Halitosis
The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.
Objective: To compare three different oral hygiene regimens regarding plaque index (PI), bleeding on probing (BOP), the number of deepened periodontal pockets ≥4 mm (PPD), oral halitosis, and changes in oral health-related…
- Trial name
- e-DENT II (NCT07166224)
- Testing
- Oral-B Powered toothbrush, Dual-Light aPDT Treatment - Lumoral
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Blekinge Institute of Technology
Community-acquired Pneumonia
Impact on the Use of Antibiotics of a Multimodal Algorithm for the Diagnosis and Management of Acute Community-acquired Pneumonia in the Emergency Room
Reducing antibiotics prescription is still to date, the main goal in low respiratory tract infections (LRTI). Several studies have shown conflicting results on the impact of multiplex PCR as a point of care tool.
- Trial name
- PROMCAP (NCT05657275)
- Testing
- CRP dosage, multiplex PCR, chest scan without injection
- Where
- 2 sites in France
- Volunteers
- 295 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bloodstream Infection, Acute Myeloid Leukemia
Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia
There is no specific recommendation about antimicrobial treatment length for documented infections in chemotherapy induced febrile neutropenia.
- Conditions
- Bloodstream Infection, Acute Myeloid Leukemia, Febrile Neutropenia
- Trial name
- NCT04910698
- Testing
- Antibiotic
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Poitiers University Hospital
Infection
Use of Collatamp G Antibiotic Impregnated Sponges in the Treatment of Peri-prosthetic Total Joint Infections
The purpose of this study is to determine if Collatamp, a small flat sponge soaked with antibiotics will help to improve the success rate of the treatment of acute joint infections after a joint replacement surgery.
- Trial name
- NCT01667874
- Testing
- Collatamp G sponge
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Oral Bacteria Levels in the Mouth
Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria
The primary objective was to evaluate the antibacterial effects of two toothpastes containing 0.3% triclosan, 2% copolymer and 0.234% sodium fluoride in a silica base as compared to a control regular fluoride toothpaste on…
- Trial name
- NCT02194621
- Testing
- Total Flavor option 1, Total Flavor option 2
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Cirrhosis, Liver, Hypertension, Portal
Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal Bleeding
Whether prophylactic antibiotics should be administered in the endoscopic secondary prevention of GVB or not is unclear. In this non-inferiority trial, we are aimed to evaluate whether prophylactic antibiotics are essential in…
- Conditions
- Cirrhosis, Liver, Hypertension, Portal, Variceal Hemorrhage
- Trial name
- NCT06437964
- Testing
- No use of prophylactic antibiotics, Prophylactic Antibiotics
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract
Intraocular Steroid After Cataract Surgery Study
The use of one dose of an antibiotic and steroid injected into the eye at the end of cataract surgery is as safe and effective as the post operative use of eyedrops after cataract surgery.
- Trial name
- NCT00478764
- Testing
- intraocular triamcinolone and gatifloxicin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Dean Health System