Clinical trials: Anticoagulated Patients
Head Injury, Traumatic Brain Injury
Selective CT for Anticoagulated Head Injured Patients
The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1.
- Conditions
- Head Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Traumatic, Blunt Head Injury
- Trial name
- Can-SCAHn (NCT05364749)
- Where
- 7 sites in Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Atrial Fibrillation, Venous Thromboembolism
START-Register: Survey on Anticoagulated Patients Register
This is a phase 4 cohort prospective, open, national, multicentre study that collects data on history of patients treated chronically with anticoagulant drugs, including the novel direct oral anticoagulants (DOACs).
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases or Prosthesis
- Trial name
- NCT02219984
- Testing
- Anticoagulants
- Where
- Italy
- Volunteers
- 15,410 people
- Sponsor
- GUALTIERO PALARETI
Hip Fractures, Anticoagulants and Bleeding Disorders
Caudal Block & Hip Fracture Surgery in Anticoagulated Patient
Hip fractures are common in elderly patients, and require surgery. Many elderly patients take anticoagulants for vasculopathy treatment.
- Trial name
- NCT05946863
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Coronary Artery Disease
Drug-Coated Balloon in Anticoagulated and Bleeding Risk Patients Undergoing PCI
The purpose of this study is to compare DCB with DES in stable CAD or ACS patients who are at high risk of bleeding. The hypothesis of the DEBATE trial is that the strategy using DCB and a shorter DAPT regimen is non-inferior to…
- Trial name
- DEBATE (NCT04814212)
- Testing
- Percutaneous coronary intervention using drug-coated balloon, Percutaneous coronary intervention using drug-eluting stent
- Where
- 14 sites in Finland, France and 2 more
- Volunteers
- 546 people
- Sponsor
- North Karelia Central Hospital
Lumbar Pain Syndrome, Anticoagulants and Bleeding Disorders
Caudal Analgesia & Anticoagulated Patient
Caudal analgesia is an effective intervention for lumbosacral pain. Some chronic pain patients take anticoagulants for vasculopathy treatment.
- Trial name
- NCT05946850
- Testing
- Caudal analgesia
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Anticoagulated Patients
Clinical Validation of a New Algorithm for Computerized Dosing of Vitamin K Antagonist Therapy
The purpose of this study is to determine whether the new algorithm is safety and effective in proposing the dosage and the timing of oral anticoagulant therapy.
- Trial name
- NCT01392040
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Of Perugia
Atrial Fibrillation, Venous Thromboembolism
Verification of XAPPORT: a Decision Support App for Physicians Used for Patients Anticoagulated With Rivaroxaban in Terms of Anticoagulation Management in Elective Surgery: Verification Process of Medical Decision Algorithm
This study shall determine whether XAPPORT - a mobile device app based on different guidelines, the summary of product characteristics of rivaroxaban, and clinical facts and practice - provides adequate guidance to physicians…
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Pulmonary Embolism
- Trial name
- VeriXAPPORT (NCT02900404)
- Testing
- XAPPORT, Expert Panel ("gold standard")
- Sponsor
- Bayer
Health Education, Patient Education as Topic
Efficacy of a Didactic Intervention in Anticoagulated Patients (TAOPE Study)
Background: Oral anticoagulant drugs represent an essential tool in thrombo-embolic events prevention. Most used are vitamin K antagonists (VKA), which plasma level is monitored measuring prothrombin time using the International…
- Conditions
- Health Education, Patient Education as Topic, Blood Coagulation Tests
- Trial name
- TAOPE (NCT03647254)
- Testing
- Patient education group
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Francisco Javier Navarro Moya
Anticoagulated Patients
Short-term Interruption Versus Continuous Anticoagulation in Colorectal Polypectomy
This study is designed to find out if it is safe to keep taking blood-thinning medicine during the removal of polyps from the colon or rectum.
- Trial name
- POLYPHEM (NCT07185295)
- Testing
- To maintain anticoagulant therapy during the polypectomy of colorectal lesions
- Where
- 10 sites in Spain
- Volunteers
- 481 people
- Sponsor
- Outcomes'10
Atrial Fibrillation, Venous Thromboembolism
The Portuguese Survey on Anticoagulated Patients Register (START-Portugal-Register)
Anticoagulants are used to prevent thrombotic events in patients with predisposing factors. However, the use of such therapies is associated with bleeding complications, which can be a serious safety issue.
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases or Prosthesis
- Trial name
- START-Portugal (NCT03977363)
- Testing
- Anticoagulant drugs
- Where
- Portugal
- Volunteers
- 25 people
- Sponsor
- CHAD
Atrial Fibrillation, Acute Coronary Syndrome
Assessment of the Incidence of Hemorrhagic and Ischemic Events in Post-angioplasty in Anticoagulated Coronary Patients with Atrial Fibrillation
Atrial fibrillation (AF) is a supraventricular arrhythmia characterized by uncoordinated and fast atrial activity, and coronary artery disease (chronic and acute coronary syndrome) is characterized by a generally atheromatous…
- Conditions
- Atrial Fibrillation, Acute Coronary Syndrome, Thrombosis, Hemorrhage
- Trial name
- FACOREV (NCT05068414)
- Testing
- Blood panel
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bleeding
Incidence of Late Haemorrhage After Invasive Gastroenterological Endoscopic Manoeuvre in Patients Treated With Anticoagulants Compared to Non-anticoagulated Patients
Patients on oral anticoagulant therapy with vitamin K antagonists (AVKs; warfarin and acenocoumarol) and direct oral anticoagulants (DOACs; apixaban, dabigatran, edoxaban and rivaroxaban), are advised to consider discontinuing…
- Trial name
- EMOSCOPIO (NCT07019077)
- Where
- Italy
- Volunteers
- 4,719 people
- Sponsor
- Centro Cardiologico Monzino
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Pulmonary Embolism
Prevalence Rate of Pulmonary Embolism Among Not Anticoagulated Patients
The purpose of this study is to evaluate the prevalence rate of pulmonary embolism among not anticoagulated patient older than 75 years old admitted with syncope and hospitalised in the Toulon Hospital
- Trial name
- MAXIME (NCT03525535)
- Testing
- data collection
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Long-Term Oral Anticoagulated Patients
Major Outcomes in Elderly Patients With Self-Management of Oral Anticoagulation (SPOG60+)
Self-management is safe and reliable in patients with long-term oral anticoagulation (OAC). However, no study has yet assessed the safety and efficacy of OAC self-management in elderly patients with major thromboembolic and…
- Trial name
- SPOG60+ (NCT00560911)
- Testing
- educational program for the self-management of OAC, 1 hour education - afterwards physician leaded OAC control
- Where
- 3 sites in Austria, Germany
- Volunteers
- 216 people
- Sponsor
- Medical University of Graz
Atrial Fibrillation, Stroke
Colchicine in Atrial Fibrillation to Prevent Stroke
The purpose of this study is to determine the feasibility of performing a randomized controlled trial to investigate the efficacy of an anti-inflammatory drug, colchicine, at reducing well validated markers of thrombosis…
- Trial name
- CIAFS-1 (NCT02282098)
- Testing
- Colchicine
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Population Health Research Institute
Covid19
Evolution of COVID-19 in Anticoagulated or Antiaggregated Patients (CORONA Study)
CORONA is a retrospective, observational, one center study to investigate the clinical evolution (in terms of survival and thromboembolic complications) of patients on chronic treatment with anticoagulants or antiplatelet agents…
- Trial name
- CORONA (NCT04518735)
- Testing
- Antithrombotic Therapy (anticoagulant and/or antiplatelet) before admission for Covid19
- Where
- Spain
- Volunteers
- 1,707 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Post Polypectomy Bleeding in Anticoagulated Patients, Gastrointestinal Hemorrhage
Hemorrhage Following Small Polyp Resection in the Colon in Anticoagulated Patients
One of the well-known of complications post colonic polypectomy is bleeding usually occuring in the 2-week period following the procedure. Patients treated with oral anticoagulation (e.g.
- Trial name
- NCT02375646
- Testing
- Warfarin, LMW Heparin
- Volunteers
- 286 people
- Sponsor
- Hadassah Medical Organization
Oral Anticoagulant Therapy
Dental Implants in Patients Under Oral Anticoagulant Therapy
This study evaluated the outcomes in the post-operative recovery following dental implant surgery in patients who continued on oral anticoagulated therapy (OAT) with warfarin.
- Trial name
- NCT04846114
- Testing
- Dental implant surgery
- Where
- Argentina
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Jorge Ernesto Aguilar
Total Shoulder Athroplasty
TXA in Anticoagulated Patients Study
This is a randomized, single-blind, single-center study comparing calculated total blood loss, surgical drain output and hematoma formation in anticoagulated patients who receive 2 doses of Tranexamic Acid (TXA) versus control…
- Trial name
- NCT04560010
- Testing
- Tranexamic Acid Injection (TXA)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health