Clinical trials: Antidepressive Agents, Second-Generation
Stroke
Effects on Clinical and Functional Outcome of Escitalopram in Adult Stroke Patients
Rehabilitative treatment in stroke survivors has shown to be effective in improving functional outcome and reducing dependency. Plasticity of the central nervous system, along with coping strategies and adaptations, seems to play…
- Trial name
- NCT00967408
- Testing
- Escitalopram, Rehabilitative treatment
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Antidepressive Agents, Second-Generation
Antidepressants, Emotions and Personality
Neuroticism is a personality trait described as an enduring tendency to experience negative emotional states and to respond poorly to environmental stress.
- Trial name
- NCT01946607
- Testing
- Citalopram
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Non-erosive Reflux Disease
Comparing Omeprazole With Fluoxetine for Treatment of Non Erosive Reflux Disease and Its Subgroups: a Double-blind Placebo-controlled Clinical Trial
Gastro-esophageal reflux disease (GERD) is highly prevalent, affecting up to 20% of the adult population in North America. Up to 70% of GERD patients have non-erosive reflux disease (NERD), a term used to describe symptoms…
- Trial name
- NCT01269788
- Testing
- Fluoxetine, Omeprazole
- Where
- Iran
- Volunteers
- 144 people
- Sponsor
- Tehran University of Medical Sciences
Obsessive-Compulsive Disorder
Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder
This study measures the occurrence of certain side effects linked to antidepressant use and evaluates the effectiveness of the medication sertraline plus cognitive behavioral therapy to treat people with obsessive-compulsive…
- Trial name
- NCT00382291
- Testing
- Regular Titration, Slow Titration
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Depression, Depressive Disorder
Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE)
Depression is common among elderly with an estimated prevalence of 5%. Due to ageing the national burden will double in the coming decade.
- Conditions
- Depression, Depressive Disorder, Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant, Intermediate Metabolizer Due to Cytochrome P450 CYP2D6 Variant
- Trial name
- CYSCE (NCT01778907)
- Testing
- Genotype information accompanied by a drug dosing advice
- Where
- 11 sites in Netherlands
- Volunteers
- 202 people
- Sponsor
- University of Groningen