Clinical trials: Antioxidant
Oxidative Stress
The Antioxidant Efficacy of a Product Probiotic in Research
Determine the efficacy of the investigational product versus placebo in reducing stress oxidative during the performance of a physical exercise of a certain intensity and duration.
- Trial name
- BIO (NCT03798821)
- Testing
- Lactobacillus rhamnosus, Lactobacillus casei y Bifidobacterium longum (100MG), Lactobacillus rhamnosus, Lactobacillus casei y Bifidobacterium longum (300MG)
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Preeclampsia
Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Preeclampsia is one of the most common complications of pregnancy and is characterized by high blood pressure and protein in the urine. This can cause problems in the second half of pregnancy for both the mother and fetus.
- Trial name
- CAPPS (NCT00135707)
- Testing
- Dietary Supplement/Vitamins
- Where
- 16 sites in United States
- Volunteers
- 10,154 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Gastrointestinal Neoplasms, Bronchial Carcinoma
Effect of an Antioxidant on Cancer-Cachectic Patients Undergoing Exercise Training
The purpose of the study is to tests the hypothesis, that N-acetylcysteine (a thiol-antioxidant)improves the exercise training effect on cancer patients that experience weight loss (cachexia) as assessed by muscle mass and…
- Conditions
- Gastrointestinal Neoplasms, Bronchial Carcinoma, Hodgkin Disease, Non-Hodgkin Lymphoma
- Trial name
- NCT00196885
- Testing
- N-acetylcysteine
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Acute Myocardial Infarction, Ischemia-reperfusion Injury
Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.
Background: Acute myocardial infarction (AMI) has remained a leading cause of mortality and disability worldwide. Although percutaneous coronary angioplasty (PCA) is the best treatment for these patients, paradoxically this…
- Conditions
- Acute Myocardial Infarction, Ischemia-reperfusion Injury, Reperfusion Injury, Myocardial, Reperfusion Arrhythmias
- Trial name
- NCT05215743
- Testing
- Antioxidant therapy, NaCl 0.9%
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chile
Heavy Smoker or Non-smoker
Antioxidant Effect of Aged Garlic Extract
This is a randomized, double-blind, placebo controlled, crossover study to determine the antioxidant effect of aged garlic extract. This study will also compare the oxidative status in heavy smokers with that in non-smokers.
- Trial name
- NCT02019368
- Testing
- Aged garlic extract
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Non-Alcoholic Fatty Liver Disease
Effect of Molecular Hydrogen in Patients With NAFLD
Molecular hydrogen H2 acts as antioxidant which selectively reduces cytotoxic harmful reactive oxygen species ROS and concomitantly acts as biological messenger, which mediates several signaling pathways that play cytoprotective…
- Trial name
- EMoHyNAFLD (NCT05325398)
- Testing
- HRW drink, HRW Natural Health Products Inc., Made in Vancouver, Canada
- Where
- Slovakia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Comenius University
Athlete
Effects of Coenzyme Q10 Supplementation on Oxidative Stress, Antioxidant Capacity, Inflammatory Responses, Fatigue Elimination, and Exercise Performance in Athletes
The aims of the study are 1) to compare the differences in plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances in athletes (i.e., soccer…
- Trial name
- NCT03321110
- Testing
- Coenzyme Q10
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Healthy
Impact of Exercise on Immune System and Metabolism in Football Players
Physical exercise, especially of high intensity, is a significant burden to the athlete's body. It should be emphasized that achieving high results in competitive sports requires significant, sometimes extreme, exercise loads…
- Trial name
- IEISM (NCT06201052)
- Testing
- Exercise test
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Male & Female Healthy Volunteers
Bioavailability Study of COQUN ORAL FORMULATION
The goal of the study is to evaluate the best dosage for COQUN ORAL FORMULATION in order to reach a level of plasma concentration which might assure its antioxidant effect if taken on a regular basis.
- Trial name
- NCT03819491
- Testing
- COQUN ORAL FORMULATION
- Where
- Romania
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- VISUfarma SpA
Diabetic Retinopathy
Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy
The present study aims to support previous research on antioxidant therapy effects in diabetic retinopathy outcome. The investigators intend to assess 180 patients with diabetic retinopathy in different stages (moderate, severe…
- Trial name
- NCT03702374
- Testing
- Combined antioxidant therapy
- Where
- Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Eye Diseases
Identification and Measurement of Antioxidants and Cytokines in the Anterior Chamber of Various Ocular Disorders
This study offers evaluation and treatment for patients with corneal or retinal diseases, such as corneal opacities or diabetic retinopathy.
- Trial name
- NCT04101591
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cancer
Study for the Liquid Chromatography-mass Spectrometry (LC-MS/MS) Assessment of Oxidative DNA Damage in Relation to Antioxidant Usage
The purpose of this study is to evaluate the basis for the reported good effects of antioxidant supplementation. A blood test using Mass Spectrometry will measure DNA damage which is expected to decrease with antioxidant…
- Trial name
- NCT01038024
- Testing
- 1 tablet composed of antioxidants and minerals
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Male Infertility
Supplementation for Male Subfertility
Old age, obesity, physical inactivity, environmental factors and genetics may contribute negatively to fertility in both males and females.
- Trial name
- FertEnhancer (NCT06091969)
- Testing
- Active multi-ingredient supplement (Fertility Enhancer, FE)
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Aging, Age-Related Memory Disorders
Effects of Blueberry on Cognition and Mobility in Older Adults
This study is being conducted to assess the effect of dietary blueberry supplementation on cognition and mobility in older adults.
- Trial name
- NCT01888848
- Testing
- Freeze-dried Blueberry
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- USDA Human Nutrition Research Center on Aging
Cardiovascular Diseases, Cardiovascular Abnormalities
The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults
Cardiovascular diseases (CVD), primarily heart disease and stroke, are the leading causes of death and prescription drug use in Canada.
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormalities, Heart Attack, Stroke
- Trial name
- NCT03826914
- Testing
- CardioFlex Q10
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Asthenozoospermia, Mitochondrial Damage
Evaluation of the Effects of Semen Incubation With ANDROSITOL®DGN on Sperm Motility and Mitochondrial Membrane Potential
Mitochondria is the cellular organelle responsible for the production of the energy necessary to fuel sperm motility. It has been demonstrated that mitochondrial efficiency is correlated to the fertilizing capacity of the…
- Trial name
- Androsi-Test (NCT04291495)
- Testing
- ANDROSITOL®TEST
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Catania
Arterial Stiffening, Aging
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
The purpose of this study is to find out why women's arteries stiffen as they go through menopause, and how this is affected by estrogen loss.
- Conditions
- Arterial Stiffening, Aging, Menopause
- Trial name
- SHAPE (NCT00608062)
- Testing
- GnRHant - Ganirelix acetate, Transdermal estradiol patch
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Effects of Water-soluble Olive Extract Supplementation
Six weeks of supplementation of an olive extract will: Improve antioxidant status Reduce inflammation Reduce muscle damage Improve exercise performance Improve exercise recovery as compared to a placebo.
- Trial name
- NCT01113827
- Testing
- Olive Extract
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Ischemic Reperfusion Injury
Ischemia Reperfusion: Prostaglandins and Antioxidants
The purposes of this study are two-fold. The first purpose is to determine the effect of taking vitamins on the recovery of an artery (blood vessel) following an induced temporary injury.
- Trial name
- NCT01666587
- Testing
- Antioxidant, Prostaglandin inhibitor (Ibuprophen)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Essex