Clinical trials: Antioxidant Capacity
Diabetes Mellitus, Oxidative Stress
Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals
Since diabetes has multiple etiologies and oxidative stress one of the proposed mechanisms, the objective is to determine the effect of supplementation with β-carotene to type 2 diabetics and healthy individuals, on iron…
- Conditions
- Diabetes Mellitus, Oxidative Stress, Iron Metabolism Disorders
- Trial name
- NCT01477112
- Testing
- Betacarotene, Controls. No treatment
- Where
- Venezuela
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Retinopathy of Prematurity
Effect of Vitamin E for Prevention of Retinopathy of Prematurity: A Randomized Clinical Trial.
The retinopathy of prematurity (ROP) is a public health problem, the main causes of ROP are prematurity, use of oxygen, malnutrition and oxidative stress.
- Trial name
- NCT03274596
- Testing
- Vitamin E
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Mothers, Lactation
Effect of Intracellular Content From Lactobacillus Casei CRL-431 on Antioxidant Capacity of Breast Milk
The objective of the present study was to evaluate the effect of the consumption of the intracellular content of Lactobacillus casei CRL-431 on the antioxidant capacity of breast milk
- Trial name
- NCT04335708
- Testing
- Postibiotic formulation
- Where
- Mexico
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centro de Investigación en Alimentación y Desarrollo A.C.
Healthy
High Total Antioxidant Capacity Products Added to Diet
The purpose of this study is to evaluate the antioxidant activity on skin photo induced damage of a food supplement and its anti-age properties.
- Trial name
- NCT00975728
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Protein-energy Malnutrition, Kwashiorkor
Study of Antioxidants and Oxidants in Malnourished Children
It is believed that the organs of severely malnourished children malfunction because harmful compounds called oxidants injure the tissues in these organs.
- Conditions
- Protein-energy Malnutrition, Kwashiorkor, Marasmus
- Trial name
- NCT00069134
- Testing
- sulfur amino acids
- Where
- Jamaica
- Volunteers
- 86 people
- Sponsor
- Baylor College of Medicine
Healthy
Anthocyanin & Phenolic Acids Bioavailability & Antioxidant Capacity After Consumption of Purple Wheat Products in Adults
This study will determine the bioavailability of anthocyanins and phenolic compounds from two purple wheat products, i.e. bran-enriched wholegrain purple wheat crackers and bran-enriched wholegrain purple wheat granola bars.
- Trial name
- NCT02730910
- Testing
- Purple Wheat Crackers, Purple Wheat Granola Bars
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Cystic Fibrosis
Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF
Cystic fibrosis has many health consequences. A reduction in the ability to perform exercise in patients with CF is related to greater death rates, steeper decline in lung function, and more frequent lung infections.
- Trial name
- CF-AOX (NCT02690064)
- Testing
- Acute Antioxidant, Chronic Antioxidant
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Augusta University
Xerostomia Due to Hyposecretion of Salivary Gland, Diabetes Mellitus, Type 2
The Artificial Saliva Spray Reduces Xerostomia in Diabetes Type II
In diabetes Type II the xerostomia is a quite frequent symptom. In evaluating the activity of an artificial saliva spray compared to a water gel in patients with Diabetes Type II patients had to follow a three day treatment with…
- Trial name
- NCT03452085
- Testing
- artificial saliva spray (AS), maritime throat spray (TT)
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Certmedica International GmbH
Female Breast Cancer, Older Adults
Melatonin Supplementation and Exercise Program in Breast Cancer Women
Introduction: Breast cancer (BC) remains the leading cause of cancer in women with nearly 1.4 million new cases worldwide annually and 27.000 in Spain.
- Conditions
- Female Breast Cancer, Older Adults, Exercise Trainning Progrmam
- Trial name
- MEXBSO (NCT06696378)
- Testing
- Melatonin 6 mg
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valladolid
Dyspepsia
Total Antioxidant Effects of Esomeprazole in Dyspeptic Patients Receiving Non-steroidal Anti-inflammatory Drugs
The principal investigator hypothesizes that participants receiving NSAID drugs with dyspeptic symptoms have increased production of gastric levels of free radicals.
- Trial name
- NCT00443963
- Testing
- Esomeprazole Magnesium
- Where
- United States
- Sponsor
- Medstar Health Research Institute
Stroke
Nutrition and Aerobic Exercise in Chronic Stroke
Strokes are very common in the United States and occur more in the elderly. The number of strokes is likely to double in the next 50 years.
- Trial name
- NEXIS (NCT02043574)
- Testing
- Treadmill Exercise, Stretching (control)
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- VA Office of Research and Development
Skin Aging, Hair and Scalp Health
CyanthOx™ Capsule Efficacy Study
The goal of this clinical trial is to learn whether daily intake of CyanthOx™80 capsules can improve skin, scalp, hair, and selected blood biomarkers in healthy adults after 12 weeks.
- Conditions
- Skin Aging, Hair and Scalp Health, Hair Loss
- Trial name
- NCT07774117
- Testing
- CyanthOx™80 Group
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Cardiotoxicity, Anthracycline Related Cardiotoxicity in Breast Cancer
ANTthracycline-induced Inflammation and OXidative Stress: 10-year Follow-up
The goal of this observational study is to learn about the long-term effects of anthracycline chemotherapy on inflammation, oxidative stress, and heart function in adult women with breast cancer.
- Conditions
- Cardiotoxicity, Anthracycline Related Cardiotoxicity in Breast Cancer, Breast Cancer
- Trial name
- ANTIOX-10 (NCT07680855)
- Volunteers
- 17 people
- Sponsor
- University of Chile
Total Knee Arthroplasty, Tourniquet-Induced Ischemia-Reperfusion Injury
The Effect of Propofol Infusion on Total Antioxidant Status During Tourniquet-Induced Ischemia-Reperfusion Injury
The release of tourniquet produces reactive oxygen species which can cause injury. Propofol is chemically similar to phenol-based free radical scavengers.
- Trial name
- NCT01638624
- Testing
- Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Diskapi Teaching and Research Hospital
Low HDL Cholesterol
Association Between HDL Functions and Atherosclerotic Burden in Healthy Individuals
This is a study of HDL function in healthy individuals classified in three groups according to their HDL-cholesterol levels (Low HDL-C, Intermediate HDl-C and High HDL-C), with the purpose of investigating which characteristics…
- Trial name
- NCT02106013
- Where
- Brazil
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Abdominal Obesity
INNUPREC (Nutrigenetic Intervention for the Prevention of Cardiovascular Disease)
Background: Abdominal obesity (AO) is a multifactorial disease that affects 81.6% of the Mexican population; it is characterized by the excessive accumulation of adipose tissue in abdominal region.
- Trial name
- INNUPREC (NCT06847243)
- Testing
- Nutrigenetic diet according the genetic test, Control intervention group
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
High Oxidation Stress, Oxidized LDL Level
Pilot Study to Evaluate the Effect of ENI Patented Whole Grape Extract on Antioxidant Status
This is a Randomized, Double-blind, Placebo-controlled, Pilot Study to Evaluate the Effect of ENI Patented Whole Grape Extract on Antioxidant Status.
- Trial name
- NCT01551706
- Testing
- ENI Patented Whole Grape Extract
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ethical Naturals, Inc.
Obesity
Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys
Our study aims to evaluate if the consumption of a Fruit and Vegetable Juice Concentrate (FVJC) vs. placebo can exert changes in the serum levels of Retinol Binding Protein 4 (RBP4), carotenoids, tocopherol, antioxidant capacity…
- Trial name
- FVJC (NCT00842543)
- Testing
- Fruit and Vegetable Juice Concentrate (FVJC)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Hypercholesterolemia, Healthy
Effects of Dietary Antioxidants to Prevent Cardiovascular Disease
Background \& Aims: The role of red wine in cardiovascular risk prevention has been documented by several epidemiological studies in patients and normocholesterolemic healthy individuals.
- Trial name
- RWTAC (NCT02409537)
- Testing
- red wine, resveratrol
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Aeromedical Center, Thessaloniki
Recurrent Miscarriage
Role of Sildenafil Citrate in Patients With Unexplained Recurrent Miscarriages
The purpose of this study is to determine whether sildenafil citrate is effective in improving uterine artery blood flow and oxidative stress in patients with unexplained recurrent miscarriages
- Trial name
- NCT01419392
- Testing
- Sildenafil citrate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University