Clinical trials: Antioxidant Status
Cardiovascular Risk Factors
Cocoa Extract-enriched Meals and Cardiovascular Risk in Older Population
Obesity prevalence in elderly populations has increased in the last years, and the reduction of overweight and obesity is a priority target in populations of all age ranges worldwide.
- Trial name
- NCT01596309
- Testing
- Cocoa extract
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Thyroidectomy, Oxidative Stress
Opioid-Free Versus Opioid-Based Anesthesia in Thyroid Surgery
This study will compare opioid-free anesthesia and opioid-based anesthesia in adult euthyroid patients undergoing elective thyroidectomy.
- Conditions
- Thyroidectomy, Oxidative Stress, Anesthesia
- Trial name
- OFA-OBA (NCT07864155)
- Testing
- Fentanyl (IV), Dexmedetomidine and lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Iron Deficiency (Without Anemia)
Effect of Ferrous iROn and cUrcumin sTatus on Inflammatory and Neurotrophic markErs
INTRODUCTION: Iron is a vital nutrient for many physiological processes including DNA production, oxygen transport and neuronal processes.
- Trial name
- Fe-ROUTINE (NCT04465851)
- Testing
- Ferrous Sulphate 65 mg, Curcumin, Ferrous Sulphate 18mg
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Asthma, Wheezing
Evaluation of Toxic Metals, Trace Elements and Total Antioxidant Activity in Children With Recurrent Wheezing
The purpose of this study is to evaluate hair trace elements and toxic metals and plasma total antioxidant activity in children with recurrent wheezing and to evaluate whether these toxic metals and trace elements have any impact…
- Trial name
- NCT00749528
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Periodontal Diseases, Gingival Diseases
Asprosin and Total Antioxidant/Oxidant Status in Diabetes and Periodontal Disease
The goal of this observational study is to learn about how different periodontal health status affects the levels of asprosin (a hormone) and total oxidant/antioxidant status in the gingival crevicular fluid and blood serum of…
- Conditions
- Periodontal Diseases, Gingival Diseases, Type 2 Diabetes
- Trial name
- NCT07691060
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Antioxidant Status
Rapid Effects of a Biofield Patch on Antioxidant Status and Cellular Energy
The goal for this clinical proof-of-concept study is to compare an active biofield skin patch to a placebo patch on antioxidant function and mitochondrial function.
- Trial name
- NCT07314359
- Testing
- Active dermal patch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Coronary Artery Disease, Diabetes
Benefits of Eggs in Combination With a Plant-based Diet
The main objective of the study is to demonstrate that the inclusion of eggs to a plant-based diet will not increase the risk for heart disease but will increase the concentration of lutein and zeaxanthin, two important…
- Conditions
- Coronary Artery Disease, Diabetes, Metabolic Syndrome
- Trial name
- NCT04234334
- Testing
- Consume 2 eggs with spinach per day, Egg Subsitute with spinach per day
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Menopause, Nutritional Intervention
Short-term Supplementation, Bone Turnover and Antioxidant Status in Menopause
This is a 8-week, double-blinded, placebo-controlled, randomized intervention trial to investigate the effects of Mg and Zn supplementation on antioxidant status and bone hormonal parameters.
- Conditions
- Menopause, Nutritional Intervention, Bone Diseases
- Trial name
- NCT03672513
- Testing
- Zinc Supplement, Magnesium supplement
- Where
- Spain
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Infertility, Pregnancy
Lifestyle and Fertility Study on Antioxidant Status, Diet and Early Pregnancy
Researchers believe that certain lifestyle factors can influence a couple's ability to conceive and have a baby. The ISIS Study will look at the health habits of couples who are planning their first pregnancy, and then attempt to…
- Conditions
- Infertility, Pregnancy, Fertility, Nutrition
- Trial name
- NCT00642590
- Where
- 2 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Immune Surveillance, Stem Cell Surveillance
Rapid Effects on Antioxidant Status, Immune Alertness, and Regenerative Activity
This clinical study aims at documenting rapid effects after consuming single doses of test product, when compared to consuming a placebo. A double-blind, placebo-controlled, cross-over study design will be used.
- Trial name
- NCT07142720
- Testing
- A low dose of seaweed extract, A high dose of seaweed extract
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
High Oxidation Stress, Oxidized LDL Level
Pilot Study to Evaluate the Effect of ENI Patented Whole Grape Extract on Antioxidant Status
This is a Randomized, Double-blind, Placebo-controlled, Pilot Study to Evaluate the Effect of ENI Patented Whole Grape Extract on Antioxidant Status.
- Trial name
- NCT01551706
- Testing
- ENI Patented Whole Grape Extract
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ethical Naturals, Inc.
Osteoarthritis, Knee
Evaluatıon of Nutrıtıonal Status and Total Antıoxıdant Capacıty in Osteoarthritis
This is a descriptive cross-sectional study conducted to evaluate the nutritional status and total antioxidant/oxidant capacity of individuals diagnosed with osteoarthritis.
- Trial name
- NCT05214469
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Obesity
Postprandial Response of Fresh-squeezed and Processed Orange Juice of Lean and Obese Subjects
This study aimed investigated the acute intake effect of fresh-squeezed orange juice (FOJ), processed orange juice (POJ), and an isoenergetic orange-flavored drink (control) on postprandial response of blood serum biomarkers…
- Trial name
- NCT03032120
- Testing
- Orange juice, Control
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Vitamin D Deficiency
Effects of Vitamin D3 Supplementation on Antioxidant Enzymes Status in Vitamin D3 Deficient Asthma COPD Overlap (ACO) Patients
Asthma-COPD overlap (ACO) is a new entity in the world of respiratory ailments. The respiratory tract of these patients are continuously exposed to oxidants (due to cigarette smoking) causing oxidative stress.
- Trial name
- NCT03931889
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Dietary Supplements
Effects of Astaxanthin Supplementation
Astaxanthin is a potent antioxidant and anti-inflammatory carotenoid. Research examining whether astaxanthin (AX) could counteract exercise-induced muscle damage and improve exercise capacity reported inconsistent…
- Trial name
- NCT06511960
- Testing
- Astaxanthin (12 mg/day) intervention, 36 mg/day astaxanthin intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Metabolic Syndrome
Study to Assess Antioxidant Efficacy of Spirulina on oxLDL and Lipids Metabolism on Subjects With Metabolic Syndrome
The purpose of this pilot study is to assess the beneficial effect of a spirulina water extract (product named Spirulysat®) compared to a placebo in the blood level ratio of oxidized LDL / total LDL cholesterol in subjects with…
- Trial name
- SPIROX (NCT02817620)
- Testing
- Spirulysat®
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Algosource
Interstitial Lung Diseases, Sarcoidosis
The Occurence of Inflammation and Oxidative Stress in Lung Diseases
Reactive oxygen species (ROS) are suggested to play a pivotal role in ILD. Little is known, however, about the endogenous antioxidant levels in ILD that can offer protection against ROS.
- Conditions
- Interstitial Lung Diseases, Sarcoidosis, Idiopathic Pulmonary Fibrosis, COPD
- Trial name
- NCT00512967
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy
Effects of Statins on Pro- and Antioxidant Status : Link With Statin-Associated Myopathy.
To evaluate the effects of a 8-week treatment with 80 mg/day simvastatin on prooxidant and antioxidant status at rest and after exercise, on mitochondrial respiration and calcium release in skeletal muscle, and on aérobic…
- Trial name
- NCT00285181
- Testing
- Simvastatin
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dermatitis, Allergies
Salmon in Pregnancy Study
The number of infants and children with allergic disease (dermatitis, allergies, asthma) has increased over the last several decades. This may be related to changes in diet.
- Conditions
- Dermatitis, Allergies, Asthma
- Trial name
- SiPS (NCT00801502)
- Testing
- Oily fish consumption, Control
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Diabetes Mellitus, Oxidative Stress
Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals
Since diabetes has multiple etiologies and oxidative stress one of the proposed mechanisms, the objective is to determine the effect of supplementation with β-carotene to type 2 diabetics and healthy individuals, on iron…
- Conditions
- Diabetes Mellitus, Oxidative Stress, Iron Metabolism Disorders
- Trial name
- NCT01477112
- Testing
- Betacarotene, Controls. No treatment
- Where
- Venezuela
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas