Clinical trials: Antiphospholipid Syndrome in Pregnancy
Antiphospholipid Syndrome in Pregnancy
The Value of Placental Vascularization and Placental Volume in Pregnancy in APLS
Antiphospholipid antibodies are autoantibodies directed against phospholipid-binding proteins. Among these groups of antibodies, lupus anticoagulant (LA) and anticardiolipin antibodies (aCL)
- Trial name
- NCT03505840
- Testing
- Ultrasound with Doppler and 3D technology
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Normal Pregnancy
Determination of Reference Values for Diluted Russell's Viper Venom Time (dRVVT) Specific to Pregnant Women (GRAPL)
Pregnancy is associated with significant changes in several aspects of haemostasis, especially an imbalance between procoagulant and anticoagulant factors.
- Trial name
- GRAPL (NCT06133621)
- Testing
- dosage dRVVT
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Recurrent Pregnancy Losses, Positive Anti Phospholipid Syndrome
Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Preconceptional use of low molecular weight heparin (enoxaparin) and aspirin in patient with recurrent miscarriages with positive anti phospholipid antibodies increase the implantation rate and the duration of pregnancy with low…
- Trial name
- NCT01661439
- Testing
- low molecular weight heparin (enoxeparine)
- Where
- Egypt
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Antiphospholipid (aPL)-Positive, Rheumatic Arthritis
MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)
The primary objective of this multicenter observational registry is to characterize the clinical, epidemiological, and biological profiles of individuals of Middle Eastern, North African, and Levantine ancestry, including…
- Conditions
- Antiphospholipid (aPL)-Positive, Rheumatic Arthritis, Celiac Disease, Focal Segmental Glomerulosclerosis (FSGS)
- Trial name
- MERIT (NCT07892651)
- Where
- Jordan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Axiom Bioregistry
Systemic Lupus Erythematosus, Antiphospholipid Syndrome
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
The PROMISSE Study is an observational study of 700 pregnant patients, enrolled at nine major clinical centers. The purpose of the study is 1) to determine whether certain proteins (called complement split products) that can…
- Trial name
- PROMISSE (NCT00198068)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Antiphospholipid Syndrome, Pregnancy Related
Evaluation of the Incidence of Cancer in the Follow-up of Women With 3 Consecutive Embryonic Demises Before 10 Weeks or 1 Fetal Death, According to Their Thrombophilia Status, With a Special Focus on Women With an Obstetric Antiphospholipid Symdrome (oAPS)
A number of case reports describe the association of antiphospholipid antibodies (aPL Abs) with hematological and solid organ malignancies.
- Conditions
- Antiphospholipid Syndrome, Pregnancy Related, Cancer
- Trial name
- NOHA-K (NCT03969498)
- Where
- France
- Volunteers
- 1,592 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Antiphospholipid Syndrome in Pregnancy
Placental Pathology and Inflammatory Factor Analysis of OAPS
This investigation is on placental pathological changes and inflammatory factors associated with obstetric antiphospholipid syndrome.
- Trial name
- NCT05378516
- Testing
- no intervention
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital