Clinical trials: Anxiety, Generalized
Anxiety Disorders
Efficacy, Safety and Tolerability of XBD173 in Patients With Generalized Anxiety Disorder
This study will test the efficacy, safety and tolerability of XBD173 in the treatment of generalized anxiety disorder in patients.
- Trial name
- NCT00108836
- Testing
- XBD173
- Where
- 23 sites in United States, Canada
- Volunteers
- 400 people
- Sponsor
- Novartis Pharmaceuticals
Pain, Anxiety
Pain, Anxiety, and Impacts on Oral Health-related Quality of Life for Patients With Orthodontic Treatment
The goal of this observational study is to learn about pain, anxiety, and impacts on oral health-related quality of life(OHRQoL) for patients before, during and after orthodontic treatment.
- Conditions
- Pain, Anxiety, Oral Health Related Quality of Life
- Trial name
- NCT06150911
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Worry, Anxiety
Effects of Duloxetine on Pathological Worry in Patients With Generalized Anxiety Disorder: A fMRI Study
(1) to compare the differences of neural activation of pathological worry between pre-treatment GAD patients and normal subjects; (2) to measure the differences of brain activation on worry in GAD patients before and after…
- Trial name
- NCT00491348
- Testing
- duloxetine hydrochloride
- Where
- Taiwan
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anxiety Disorders, Mental Health
St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD)
This study will determine whether the herbal product St. John's wort is safe and effective in treating generalized social anxiety disorder (GSAD). Study hypothesis: Hypericum perforatum (St.
- Trial name
- NCT00118833
- Testing
- Hypericum perforatum (St. John's wort)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
General Anxiety Disorder
Evaluate the Beneficial Effects of an Oral Nutritional Supplement Based on Leonurus Cardiaca for the Improvement of Mood and Anxiety
This study aims to evaluate the efficacy and safety of Leonurus cardiaca extract in reducing anxiety symptoms in adults with Generalized Anxiety Disorder (GAD).
- Trial name
- LEONORUS (NCT06954038)
- Testing
- Leonurus cardiaca extract 250 mg, Leonurus cardiaca extract 500 mg
- Volunteers
- 60 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Anxiety Disorders
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.
- Trial name
- EV-SoPRANO (NCT04221997)
- Testing
- sertraline
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Generalized Anxiety Disorder
A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder (3)
This is a 10-week trial that evaluates the efficacy and safety of PD 0332334 in subjects ages 18 and older with generalized anxiety disorder.
- Trial name
- NCT00658762
- Testing
- PD 0332334, paroxetine
- Where
- 28 sites in United States, Hungary
- Volunteers
- 286 people
- Sponsor
- Pfizer
Generalized Anxiety Disorder
Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety Disorder
The purpose of this study is to evaluate the efficacy, safety and tolerability of vilazodone relative to placebo in the treatment of generalized anxiety disorder (GAD)
- Trial name
- VLZ-MD-05 (NCT01629966)
- Testing
- Vilazodone
- Where
- 37 sites in United States
- Volunteers
- 680 people
- Sponsor
- Forest Laboratories
Generalized Anxiety Disorder, Social Anxiety Disorder
Metacognitive Therapy Compared to Cognitive-behavioral Therapy
This is a qualitative study of participants who have taken part in a randomized controlled trial comparing transdiagnostic metacognitive therapy and disorder-specific cognitive-behavioral therapy for anxiety disorders.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07382323
- Testing
- Transdiagnostic metacognitive therapy, Disorder-specific cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Generalized Anxiety Disorder
Duloxetine for the Treatment of Generalized Anxiety Disorder
This is a 15 week study comparing how well duloxetine and placebo treatments improve generalized anxiety disorder
- Trial name
- NCT00803361
- Testing
- Duloxetine
- Where
- 7 sites in China
- Volunteers
- 210 people
- Sponsor
- Eli Lilly and Company
Generalized Anxiety Disorder
Exercise Training for the Treatment of Generalized Anxiety Disorder
The purpose of this study is to compare the effects of 6 weeks of endurance or strength training and a wait list comparison condition on symptoms of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT00953654
- Testing
- Strength Training, Endurance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Georgia
Generalized Anxiety Disorder
Tandospirone Citrate in the Treatment of Patients With Generalized Anxiety Disorder
The purpose of this study is to evaluate the efficacy and safety of comparative high dose Tandospirone Citrate in the treatment of patients with generalized anxiety disorder.
- Trial name
- TACGAD (NCT01614041)
- Testing
- Usual dose treatment of Tandospirone, Comparative high dose of tandospirone treatment
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Marubeni Pharmaceuticals (Suzhou) Co., Ltd.
Anxiety, Obsessive Compulsive Disorder
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. Investigators aim to enhance this therapy with the use of virtual reality exposures and to make therapy more…
- Trial name
- NCT02713516
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD)
Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders
The primary goal of this randomized controlled trial is to compare the effectiveness of two transdiagnostic psychological treatments, Metacognitive Therapy (MCT) and the Unified Protocol for Transdiagnostic Treatment of Emotional…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Panic Disorder (With or Without Agoraphobia)
- Trial name
- NCT06971692
- Testing
- Metacognitive therapy (MCT), Unified protocol (UP)
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Karolinska Institutet
Anxiety Disorders
Therapeutic Effect of an Herbal Medicine on Anxiety
Phase III, double blind, randomized study, controlled by Valeriana officinalis L for evaluating the efficacy of association of Passiflora incarnata L; Crataegus Oxyacantha L and Salix alba L. in generalized anxiety disorder.
- Trial name
- NCT01178632
- Testing
- Passiflora, Valeriana officinalis
- Where
- Brazil
- Volunteers
- 136 people
- Sponsor
- Millet Roux
Depression, Anxiety Disorders
Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT
Depression and anxiety are common mental health problems. There are effective treatments for depression and anxiety and one of these is talking therapies using cognitive behaviour therapy (CBT).
- Conditions
- Depression, Anxiety Disorders, Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- D-IAPT (NCT03188575)
- Testing
- SilverCloud Internet-delivered Cognitive Behavioural Therapy, Waiting List
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- Silver Cloud Health
Post-traumatic Stress Disorder (PTSD)
A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
- Trial name
- NCT05189977
- Testing
- Propranolol, Prazosin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Generalized Anxiety Disorder, Major Depressive Disorder
Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in Pakistan
This study aims at developing an online system for the remote delivery of EMDR therapy in Pakistan. Moreover, this study will compare the efficacy of online EMDR therapy with face-to-face EMDR therapy.
- Conditions
- Generalized Anxiety Disorder, Major Depressive Disorder, Social Anxiety Disorder, Somatic Symptom
- Trial name
- NCT05785312
- Testing
- Online EMDR Therapy System, Face to Face Eye Movement Desensitization & Reprocessing Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Anxiety Disorders, Mood Disorders
Treating Emotional Disorders in Primary Care With Psychological Techniques
The strong demand for primary care (PC) services in Spain exceeds resources. Part of this demand is due to the increasing number of anxiety, depression, and somatization disorders that affect the general population.
- Conditions
- Anxiety Disorders, Mood Disorders, Somatization Disorder, Pain Disorder
- Trial name
- PsychPC (NCT01903096)
- Testing
- Cognitive Behavioral Treatment, Primary Care Treatment As Usual
- Where
- Spain
- Volunteers
- 1,126 people
- Sponsor
- Psicofundación: Fundación Española para Promoción, Desarrollo Científico y Profesional de la Psicolo
Pregnancy
on General Well-being, Anxiety, and Physical Activity in Pregnant Women
102 pregnant women will be randomly divided into 2 groups. Participants in the control group will be given pregnancy counseling that includes only nutrition, walking (3 days a week for 30 minutes), and breathing exercises, and…
- Trial name
- Qigong (NCT07023978)
- Testing
- Some movements in the qigong study called Ba Duan Jin, which will be applied to pregnant women, will be arranged for pregnant women and explained in detail. These are very slow, movements
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kocaeli University