Clinical trials: Anxiety, Generalized
Generalized Anxiety Disorder, Separation Anxiety Disorder
Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep
1 out of 8 children, adolescents, and young adults suffer from an anxiety disorder. Studies over the past decade show that selective serotonin-reuptake inhibitors (SSRIs), a class of medication that treats anxiety in adults, also…
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- NCT02189213
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Anxiety Disorders
A Study To Evaluate PRX-00023 In Patients With Generalized Anxiety Disorder (GAD)
This is a randomized, double-blind, placebo controlled, multi-center outpatient study, in adults with GAD. Patients 18-65 years of age, with the diagnosis of GAD according to DSM-IV criteria, who fulfill the inclusion/exclusion…
- Trial name
- NCT00248183
- Testing
- PRX-00023
- Where
- 20 sites in United States
- Volunteers
- 310 people
- Sponsor
- Epix Pharmaceuticals, Inc.
Generalised Anxiety Disorder
A Non-randomized Controlled Trial Was Conducted to Observe the Improvement in the Level of HAMA in Patients With Generalized Anxiety Disorder During the 6-week Period of Oral Treatment With Chaihu Jia Longgu Muli Tang (Bupleurum Plus Dragon Bone and Oyster Shell Decoction) Combined With Sertraline.
The purpose of this study is to clinically observe the efficacy of Bupleurum Plus Dragon Bone and Oyster Shell Decoction in the treatment of Generalized Anxiety Disorder to improve the scores of HAMA
- Trial name
- NCT06725771
- Testing
- Bupleurum Plus Dragon Bone and Oyster Shell Decoction Combined with Sertraline, Sertraline Hydrochloride Tablets
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Lin Xiaoqian
General Anxiety Disorder
A Dose-Response Safety Study of ENX-102 in Patients With GAD
This is a randomized, double-blind, placebo-controlled study to evaluate the safety and tolerability of ENX-102 and determine a dose-response for the effects of ENX-102 in patients with GAD
- Trial name
- NCT06653296
- Testing
- ENX-102
- Where
- 3 sites in United Kingdom
- Volunteers
- 38 people
- Sponsor
- Engrail Therapeutics INC
Generalized Anxiety Disorder
RCT of Short-Term Psychoanalytic vs. Cognitive Behavioral Therapy for GAD
This study is a randomized controlled trial designed to compare the effectiveness of two types of short-term psychotherapy-psychoanalytic therapy and Cognitive Behavioral Therapy (CBT)-in treating Generalized Anxiety Disorder…
- Trial name
- (RCT-GAD) (NCT06831708)
- Testing
- Psychoanalytic Psychotherapy, Cognitive Behavioral Therapy (CBT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beykoz University
Posttraumatic Stress Disorder, Major Depressive Disorder
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI).
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05527509
- Testing
- Emotional Resilience Skills Training (ERST), Active Monitoring
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Regina
Depression NOS, Generalized Anxiety Disorder
Metacognitive Therapy for Depression and Generalized Anxiety Disorder in Primary Care, Blended Version of Mediated Treatment
The goal of this clinical trial is to investigate a new format of metacognitive therapy (MCT) for primary care patients with depression or generalized anxiety disorder (GAD) called blended MCT (bMCT).
- Trial name
- NCT06928428
- Testing
- Metacognitive therapy, blended format
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Stockholm
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Anxiety Disorders
Efficacy Study of Abdominal Massage Therapy to Treat Generalized Anxiety Disorder of Deficiency of Both Heart and Spleen Type
Generalized Anxiety Disorder (GAD) is characterized by the presence of persistent worry or fear of no explicit object and fixed content, or things that might occur in real life，which not corresponds with the realities.
- Trial name
- NCT02186366
- Testing
- Abdominal Massage Therapy, Buspirone
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sun Qing
Anxiety Disorders
Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults With Generalized Anxiety Disorder.
A 12-Month, Open-Label, Flexible-Dosage Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults with Generalized Anxiety Disorder.
- Trial name
- NCT00214994
- Testing
- Gabitril
- Where
- 93 sites in United States, Canada
- Sponsor
- Cephalon
Generalized Anxiety Disorder
A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder
The purpose of this study is to evaluate the safety and efficacy of an investigational anti-anxiety medication relative to placebo in patients with generalized anxiety disorder (GAD)
- Trial name
- NCT00236054
- Testing
- Gabitril
- Where
- 19 sites in United States
- Volunteers
- 440 people
- Sponsor
- Cephalon
Anxiety Disorders, Generalized Anxiety Disorder
Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children
Anxiety disorders are the most common form of psychopathology, and frequently begin in childhood, resulting in lifelong impairment.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05503017
- Testing
- Psycho-social, computerized intervention targeting error sensitivity, Psycho-social, computerized intervention on healthy lifestyle choices
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Florida State University
Schizophrenia, Major Depressive Disorder
PHARMO Institute Seroquel Safety Study
The purpose of this observational study is to study specific outcomes of interest in users of quetiapine compared with all other atypical antipsychotics and specifically olanzapine and risperidone.
- Conditions
- Schizophrenia, Major Depressive Disorder, Bipolar Disorder, Generalized Anxiety Disorder
- Trial name
- PHARMO II (NCT01342120)
- Volunteers
- 18,325 people
- Sponsor
- AstraZeneca
Treatment Adherence, Generalized Anxiety
Cerina-A Pilot Randomized Controlled Trial
The goal of this pilot Randomized Controlled Trial is twofold: 1) To learn about the feasibility and usefulness of a mobile application for generalised anxiety symptoms (Cerina); 2) To test the preliminary effects of Cerina in…
- Conditions
- Treatment Adherence, Generalized Anxiety, Treatment Adherence and Compliance
- Trial name
- Cerina (NCT06146530)
- Testing
- Treatment
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Cerina Therapeutics
Preoperative Anxiety
Music for Reducing Anxiety Before Surgery
The goal of this clinical trial is to learn whether listening to self-selected music through headphones for 30 minutes before surgery lowers state anxiety in adults waiting for elective surgery.
- Trial name
- NCT07902765
- Testing
- music listening
- Where
- Vietnam
- Volunteers
- 92 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Generalized Anxiety Disorder, Panic Disorder
Treatment of Late-life Anxiety in Primary Care Settings
The research study proposed is designed to examine the outcomes of a cognitive behavioral guided self-care intervention with older adults diagnosed with generalized anxiety disorder and recruited from a primary care setting.
- Conditions
- Generalized Anxiety Disorder, Panic Disorder, Anxiety Disorder Not Otherwise Specified
- Trial name
- NCT00938093
- Testing
- Cognitive behavioral therapy, Enhanced usual care
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Generalized Anxiety Disorder
Stress Reduction and Anxiety: Effects on the Function and Structure of the Brain
The aim of the study is to test whether Generalized Anxiety Disorder (GAD) patients that participate in a Stress Reduction Intervention show a brain activation pattern (assessed by MRI) indicative of improved emotion regulation…
- Trial name
- NCT01128309
- Testing
- Stress Reduction Intervention, Active Control intervention
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Massachusetts General Hospital
Anxiety Disorders
Duloxetine Compared With Placebo in the Prevention of Relapse in Generalized Anxiety Disorder
This is a clinical trial assessing the time to relapse of anxiety symptoms among patients with generalized anxiety disorder who have responded to duloxetine therapy.
- Trial name
- NCT00122863
- Testing
- Duloxetine Hydrochloride
- Where
- 47 sites in United States, Austria and 5 more
- Volunteers
- 380 people
- Sponsor
- Eli Lilly and Company
Generalized Anxiety Disorder, Social Anxiety Disorder
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03925987
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Social Anxiety Disorder, Generalized Anxiety Disorder
Where We All Meet: ACT Approach to Adolescents Anxiety Disorders
Transdiagnostic approaches have been proposed as more truthfully representing mental health problems. Acceptance and Commitment Therapy (ACT) is a transdiagnostic approach that proposes Psychological Inflexibility/Flexibility…
- Trial name
- NCT05906849
- Testing
- ACT for anxiety disorders
- Where
- Portugal
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Coimbra