Clinical trials: Anxiety, Generalized
ADHD, Depression Disorders
Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
The study aims to verify if the Gaize ocular device can effectively identify eye movements indicative of prescribed psychotropic medication usage by employing Drug Recognition Expert (DRE) testing protocols within a controlled…
- Conditions
- ADHD, Depression Disorders, Mood Disorders, Anxiety Disorder Generalized
- Trial name
- Rx Meds Gaize (NCT07389473)
- Testing
- Prescription Psychotropic Medications
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gaize
Fiberoptic Bronchoscopy
50% Nitrous Oxide and 50% Oxygen (MEOPA) Conscious Sedation Versus Placebo in Fiberoptic Bronchoscopy
Fiberoptic bronchoscopy may generate pain, anxiety or cough and dyspnea. It may then induce discomfort and then run down its yield.
- Trial name
- NCT00392522
- Testing
- 50% Nitrous Oxide and 50% Oxygen (MEOPA)
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Social Anxiety Disorder, Generalized Anxiety Disorder
Visual Mismatch Negativity in Attention Bias Modifcation Treatment for Anxiety
this study examines the emergence of the visual mismatch negativity (vMMN) ERP component in response to deviations from the embedded contingency in attention bias modification treatment (ABMT) for social and generalized anxiety…
- Trial name
- NCT03016052
- Testing
- ABMT
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel Aviv University
Hoarding Disorder, Virtual Reality Based Therapy
Non-Immersive Virtual Environments for the Treatment of Hoarding Disorder
This experimental trial investigates whether Virtual Reality Exposure (VRe) helps individuals reduce the difficulty of discarding personal possessions. It will also evaluate the psychological state impacts of the intervention.
- Conditions
- Hoarding Disorder, Virtual Reality Based Therapy, General Population (no Specific Condition or Disease)
- Trial name
- HD&VR (NCT07160543)
- Testing
- Imagination Exposure, Non-immersive Virtual Reality Exposure
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Depression, Anxiety
Effect of General and Non-general Anesthesia on Perioperative Depression or Anxiety
Perioperative depression and/or anxiety play a critical role in patient presentation, satisfaction and outcomes. The aim of this study is to assess the level of perioperative depression and/or anxiety in patients with…
- Trial name
- NCT05315648
- Testing
- anesthesia approach (general anesthesia or non-general anesthesia)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT
This study is a pivotal, randomised, controlled, non-inferiority trial evaluating "Nook," an AI-delivered, neurosymbolic, clinician-supervised digital psychological intervention for depression and anxiety, compared with standard…
- Trial name
- NCT07620340
- Testing
- AI-Digital CBT, Cognitive Behavioural Therapy
- Volunteers
- 400 people
- Sponsor
- PsyScale
Generalized Anxiety Disorder (GAD), Worrying
Text Message Safety Behavior Fading for Pathological Worry
The current study aims to explore the efficacy of a text message-based Safety Behavior Fading Intervention compared to a PMR control condition.
- Conditions
- Generalized Anxiety Disorder (GAD), Worrying, Anxiety
- Trial name
- NCT07391020
- Testing
- Safety Behavior Fading for Pathological Worry, Progressive Muscle Relaxation (PMR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida State University
Generalised Anxiety Disorder
A Neuro-Technological Intervention for Adolescents With GAD
This study aims to evaluate the safety and acceptability of a basic neuro-technological intervention in the treatment of adolescents with Generalised Anxiety Disorder (GAD).
- Trial name
- NCT03813290
- Testing
- Neuro-technological Intervention
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National Healthcare Group, Singapore
Generalized Anxiety Disorder, Social Phobia
Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety disorders in community health centers.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
- Trial name
- NCT01416805
- Testing
- Computerized Cognitive Behavioral Therapy, Treatment as usual
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Disorders
Effectiveness of Long-Term Versus Short-Term Treatment of Generalized Anxiety Disorder With Venlafaxine XR
This study will assess the effectiveness of venlafaxine XR, randomized to either venlafaxine XR or placebo in preventing the relapse of generalized anxiety disorder after 6 months of treatment versus 12 months of treatment.
- Trial name
- NCT00183274
- Testing
- Venlafaxine XR
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- University of Pennsylvania
Generalized Anxiety Disorder
Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD Subjects
To determine the safety and efficacy of SEP-225441 (eszopiclone) in subjects with generalized anxiety disorder (GAD).
- Trial name
- NCT00616655
- Testing
- eszopiclone
- Where
- 57 sites in United States
- Volunteers
- 456 people
- Sponsor
- Sumitomo Pharma America, Inc.
Depression Disorders, Bipolar Affective Disorder
Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
This study maps the current epidemiological situation of mental disorders in Slovakia. The aim of the study is to determine the prevalence of selected mental disorders in the adult population of the Slovak Republic, assess the…
- Conditions
- Depression Disorders, Bipolar Affective Disorder, Generalized Anxiety Disorder (GAD), Panic Disorder
- Trial name
- EpiMentDisSK (NCT07129408)
- Where
- Slovakia
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Comenius University
Generalized Anxiety Disorder
Continuous Theta Burst Stimulation for Generalized Anxiety Disorder
This randomized, rater-blinded clinical trial evaluates the effectiveness, safety, and tolerability of continuous theta burst stimulation (cTBS) in adults with generalized anxiety disorder (GAD).
- Trial name
- NCT07770919
- Testing
- Continuous Theta Burst Stimulation of the Right Posterior Parietal Cortex, Continuous Theta Burst Stimulation of the Right Dorsolateral Prefrontal Cortex
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Military Hospital 175
Children, Ambulatory Surgery
Analysis of the Link Between Flow State and Preoperative Anxiety in Children Undergoing Playful Distraction
This study focuses on preoperative anxiety in children and non-drug methods to reduce anxiety. During surgery under general anesthesia, children may be anxious because of separation from their parents, fear of anesthesia, or loss…
- Conditions
- Children, Ambulatory Surgery, General Anesthesia
- Trial name
- ALFA (NCT04079244)
- Testing
- Video game, Animated cartoon
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
Generalized Anxiety Disorder, Chest Pain
Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room
The goal of this research is to compare the benefits and risks of three anxiety treatments that are pragmatic, graduated in the level of resource intensity, and have demonstrated efficacy and feasibility for real world adoption.
- Conditions
- Generalized Anxiety Disorder, Chest Pain, Panic
- Trial name
- PACER (NCT04811521)
- Testing
- Primary care follow-up, Online Self-Administered Anxiety Management Program plus Peer Support Guidance, Therapist-Administered Cognitive Behavioral Therapy
- Where
- 5 sites in United States
- Volunteers
- 375 people
- Sponsor
- Indiana University
Generalized Anxiety Disorder
Virtual Reality for Generalized Anxiety Disorders
The goal of this clinical trial is to apply Virtual Reality as an adjunct treatment for Generalized Anxiety Disorder. The main question it aims to answer are: Determination of the efficacy of VR modules as an adjunct therapy in…
- Trial name
- VR-GAD (NCT05895721)
- Testing
- Virtual Reality
- Where
- 5 sites in Malaysia
- Volunteers
- 80 people
- Sponsor
- Clinical Research Centre, Malaysia
Anxiety Generalized
A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms
This is a Phase 2, multi-center, randomized, double-blind, parallel-group, dose-finding study to assess the effect of 4 doses of MM120 (25, 50, 100 or 200 μg freebase-equivalent) for the treatment of anxiety symptoms in subjects…
- Trial name
- NCT05407064
- Testing
- MM120
- Where
- 22 sites in United States
- Volunteers
- 198 people
- Sponsor
- Definium Therapeutics US, Inc.
Depressive Disorder, Major
Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder
The proposed study is for a 6 week open-label clinical trial in which Seroquel XR is added to a selective serotonin reuptake inhibitor (SSRI) medication for the treatment of depressive and/or anxiety symptoms.
- Trial name
- NCT00892463
- Testing
- Quetiapine (Seroquel) XR
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Sunnybrook Health Sciences Centre
Generalized Anxiety Disorder
Attention Training for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) has high prelevance (up to 8.5%; Roy-Byrne \& Wagner, 2004) and leads to functional impairment (Wittchen et al., 2002; Ballenger et al., 2001).
- Trial name
- NCT00602563
- Testing
- AMP, Applied Relaxation (AR), Clinical Monitoring (CM)
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- San Diego State University