Clinical trials: Anxiety, Generalized
Depressive Symptoms, Generalized Anxiety, or Psychological Stress
Mobile Intervention for Mental Health of Family Caregivers in Thailand
The primary objective of this study is to evaluate the effectiveness of the CAMMA intervention in reducing psychological distress among family caregivers of adults with chronic conditions in Thailand.
- Trial name
- NCT06722287
- Testing
- Caregiver Mental Health Mobile Application (CAMMA) Intervention, Usual Care Group
- Where
- Thailand
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Attention Deficit Hyperactivity Disorder, Anxiety, Separation
Treatment of Youth With ADHD and Anxiety
The purpose of this NIMH-sponsored pilot study is to collect information on the efficacy and safety of drug treatments for children and adolescents who suffer from both ADHD and anxiety disorders.
- Conditions
- Attention Deficit Hyperactivity Disorder, Anxiety, Separation, Social Phobia, Generalized Anxiety Disorder
- Trial name
- NCT00012584
- Testing
- methylphenidate, fluvoxamine
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder, Obsessive-Compulsive Disorder
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe.
- Conditions
- Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder
- Trial name
- Expedition (NCT06376734)
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Brigham and Women's Hospital
Depression, Anxiety Disorders
Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT
Depression and anxiety are common mental health problems. There are effective treatments for depression and anxiety and one of these is talking therapies using cognitive behaviour therapy (CBT).
- Conditions
- Depression, Anxiety Disorders, Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- D-IAPT (NCT03188575)
- Testing
- SilverCloud Internet-delivered Cognitive Behavioural Therapy, Waiting List
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- Silver Cloud Health
Generalized Anxiety Disorder (GAD), Major Depressive Disorder
Therapy and Tech Study
The investigators want to test if gen AI can support therapy by recruiting patients already in therapy.
- Trial name
- NCT07225192
- Testing
- Chatbot Therapy
- Volunteers
- 204 people
- Sponsor
- University of California, Irvine
Anxiety Disorders
Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning
The purpose of this study is to increase researchers understanding of the biological basis of generalized anxiety disorder and social anxiety disorder.
- Trial name
- NCT00062517
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Generalized Anxiety Disorder
A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)
A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Generalized Anxiety Disorder - Voyage
- Trial name
- NCT06741228
- Testing
- DT120
- Where
- 34 sites in United States
- Volunteers
- 214 people
- Sponsor
- Definium Therapeutics US, Inc.
Anxiety Disorder Generalized
A Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety Disorder
This is a multicenter, randomized, double-blind, placebo- and active-controlled study to assess the efficacy and safety of CD-008-0045 in patients with generalized anxiety disorder (GAD).
- Trial name
- NCT04598867
- Testing
- CD-008-0045, Afobazol
- Volunteers
- 200 people
- Sponsor
- ChemRar Research and Development Institute, LLC
Generalized Anxiety Disorder
Cognitive Behavior Treatment of Older Adults With Generalized Anxiety Disorder in Primary Care
The purpose of this study is to determine whether cognitive behavior treatment (CBT) can be delivered effectively by providers of different expertise levels in adults age 60 and older in a primary care setting.
- Trial name
- NCT00765219
- Testing
- CBT, Usual Care
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety, Anger
Experiences of Anger in Patients in Primary Health Care With Symptoms of Generalized Anxiety
Symptoms of generalized anxiety is common in the general population and is often treated in primary health care. Anger is an emotion that can lead to interpersonal problems but can also be an agent for justice and change.
- Conditions
- Generalized Anxiety, Anger, Primary Health Care
- Trial name
- NCT04702711
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Kronoberg County Council
Generalized Anxiety Disorder
Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study
The goal of this feasibility study is to determine the tolerability and safety of add on treatment with L-methylfolate in patients with treatment-resistant generalized anxiety disorder (GAD).
- Trial name
- NCT06218030
- Testing
- L-methylfolate
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Queen's University
Generalized Anxiety Disorder
Implementation of Psychological Treatment in Generalized Anxiety
Pragmatic randomized controlled trial (expected N = 80) of cognitive-behavioral therapy (CBT) to contrast two psychotherapeutic implementation strategies (State-of-the-Art welcome phase vs. prolonged focus on sudden changes).
- Trial name
- IMPLEMENT2_0 (NCT03079336)
- Testing
- Implementation - SOTA, Implementation - Prolonged focus on changes, Mastery your Anxiety and Worry (MAW)
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Obsessive-Compulsive Disorder, Anxiety Disorders
Improving Access to Child Anxiety Treatment
There is strong evidence that cognitive behavioral therapy (CBT) with exposure is the preferred treatment for youth with anxiety disorders, but outpatient services that provide this type of treatment are limited.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety
- Trial name
- IMPACT (NCT03528109)
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 379 people
- Sponsor
- Bradley Hospital
Anxiety Disorders
An Investigation of General Predictors for CBT Outcome for Anxiety Disorders in a Naturalistic Setting
The aim of this study is to investigate the predictive value of emotion regulation and attentional control for outcome of Cognitive Behavioural Therapy for adults with anxiety disorders in a naturalistic setting.
- Trial name
- NCT02638363
- Testing
- Cognitive behavioral therapy
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Copenhagen
Obsessive Compulsive Disorder (OCD), Bipolar Disorders
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
This is a research study looking at whether the way people speak can help predict how well they'll respond to certain mental health treatments.
- Conditions
- Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD
- Trial name
- NCT06823024
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Psyrin Inc.
Generalized Anxiety Disorder
Anxiety Symptoms in Relation to Use of Hemp-derived, Full Spectrum Cannabidiol (CBD)
Generalized anxiety disorder affects about 6.8 million adults in the United States, therefore its treatment is of major public health interest.
- Trial name
- NCT05023759
- Testing
- Formula30A Full Spectrum Hemp Cannabidiol 25mg Capsules
- Where
- 6 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- Formula30A LLC
Major Depressive Disorder, Generalized Anxiety Disorder
Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat
The primary objective of the study is to determine whether quetiapine extended-release in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo in treating depressive and anxiety symptoms in…
- Trial name
- NCT01971203
- Testing
- seroquel xr, CBT
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Generalized Anxiety Disorder
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
A Phase 3, Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Generalized Anxiety Disorder - Panorama
- Trial name
- NCT06809595
- Testing
- DT120
- Where
- 36 sites in United States, Czechia and 4 more
- Volunteers
- 245 people
- Sponsor
- Definium Therapeutics US, Inc.
Anxiety Disorder (Panic Disorder or GAD), Well Being
Religiously Integrated Cognitive Behavioral Therapy
This study aims to examine the effect of a newly developed religously oriented cognitive behavioral group therapy program on the level of anxiety and well-being in young adults compared to the traditional cognitive behavioral…
- Trial name
- NCT07334769
- Testing
- Religiosly Integrated Cognitive Behavioral GroupTherapy, Traditional Cognitive Behavioral Group Therapy, Waiting Group
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ibn Haldun University
Anxiety Disorders, Depressive Disorder
Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression
The goal of this clinical trial is to test the efficacy of a transdiagnostic Internet-delivered interventions for Romanian adolescents with anxiety and/ or depression.
- Conditions
- Anxiety Disorders, Depressive Disorder, Social Anxiety Disorder, Major Depressive Disorder
- Trial name
- NEURO4C (NCT06724666)
- Testing
- Transdiagnostic Internet-delivered intervention
- Where
- 2 sites in Romania
- Volunteers
- 198 people
- Sponsor
- Babes-Bolyai University