Clinical trials: Anxiety, Generalized
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia
INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1
The focus of this study is not about what it is like to have a mental disorder, but instead the diagnostic experience. Some people find diagnoses helpful, but some find them upsetting and harmful.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia, Generalised Anxiety Disorder, Bipolar Disorder
- Trial name
- INCLUDE (NCT03131505)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Generalized Anxiety Disorder
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
The purpose of this study is to determine if treatment with a single and/or repeat dose of RE104 for Injection reduces anxiety symptoms in participants with Generalized Anxiety Disorder (GAD) as compared to placebo.
- Trial name
- NCT07489651
- Testing
- RE104 for Injection
- Where
- 28 sites in United States
- Volunteers
- 160 people
- Sponsor
- Reunion Neuroscience Inc
Major Depressive Disorder, Generalized Anxiety Disorder
Internet-delivered Cognitive Behavioral Treatment of Depression and Anxiety in Latin American College Students
The aim is to evaluate short term and longer term treatment effects of internet-delivered cognitive behavioral therapy compared to treatment as usual for college students with anxiety and/or depression in low-middle income…
- Trial name
- NCT04780542
- Testing
- Yo Puedo Sentirme Bien- Clinician-Guided version, Yo Puedo Sentirme Bien- Self-Guided version
- Where
- 8 sites in Colombia, Mexico
- Volunteers
- 1,500 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Anxiety Disorders, Generalized Anxiety Disorder
Treatments for Anxiety: Meditation and Escitalopram
We propose the first randomized, controlled study to assess the comparative effectiveness of Mindfulness-Based Stress Reduction (MBSR) with a medication for anxiety disorders.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- TAME (NCT03522844)
- Testing
- Mindfulness-Based Stress Reduction, Escitalopram
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- Georgetown University
Anxiety
Sleep, Dreaming, and Virtual Reality for Mental Health
People spend approximately one-third of their lives asleep, yet sleep is often underused as an opportunity to support psychological well-being.
- Trial name
- NCT07408206
- Testing
- Dream Yoga Inspired Intervention, Sleep Health Enhancement Program (SHEP)
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Separation Anxiety Disorder, Social Anxiety Disorder
Effectiveness Study of CBT for Anxiety in Children
The study aims to evaluate the effectiveness of a cognitive behaviour therapy program (FRIENDS) for anxiety disorders in children aged 8-15 years who have been referred to child and adolescent mental health clinics in Western…
- Conditions
- Separation Anxiety Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- ATACA (NCT00586586)
- Testing
- Cognitive behavioural therapy
- Where
- Norway
- Volunteers
- 222 people
- Sponsor
- Haukeland University Hospital
Orthopedic Disorder, Anxiety
Brachial Plexus Block vs. General Anesthesia for Anesthesia Anxiety Before Orthopedic Upper Extremity Surgery
Surgical procedures and anesthesia applications are situations in which people do not feel safe due to the current vital risks. Anxiety is a natural reaction that occurs in such situations, it manifests itself with worry and…
- Conditions
- Orthopedic Disorder, Anxiety, Upper Extremity Injury, Surgery
- Trial name
- NCT05476198
- Testing
- Brachial plexus block, General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
General Anxiety Disorder
Interactive Voice Based Administration of the GAD 7
This study investigates a new delivery method for the General Anxiety Disorder - 7 (GAD 7), a clinically accepted tool for diagnosing general anxiety disorder.
- Trial name
- NCT04990492
- Testing
- Paper GAD 7, Voice Administered GAD 7
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Generalized Anxiety Disorder, Social Anxiety Disorder
Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study
This proposed study aims to evaluate the efficacy of a daily oral cannabinoid oil preparation in treating symptoms of DSM-5 anxiety disorders, using a two-arm, 8-week randomized, placebo-controlled trial in adults aged 21-65…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT04569760
- Testing
- 50:2 mg(CBD:THC)/ml - Cannabinoid Oil Oral Preparation- titrated as tolerated up to a maximum 8mls twice daily (200 mg- 800 mg total dose)
- Where
- Canada
- Sponsor
- McMaster University
Attention Deficit Hyperactivity Disorder, Generalized Anxiety Disorder
A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity
Other psychiatric disorders, including anxiety, often co-occur with adult ADHD; with 85% of ADHD patients having at least one other psychiatric condition.
- Conditions
- Attention Deficit Hyperactivity Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03785223
- Testing
- Methylphenidate Hydrochloride Controlled-Release Capsules
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Bipolar Disorder, Panic Disorder
Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of quetiapine SR monotherapy and divalproex sodium ER monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT00579280
- Testing
- quetiapine SR, divalproex sodium ER
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Disorders Generalized, Depression
Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners
This pilot study engaged pregnant couples experiencing elevated symptoms of maternal anxiety or depression with an existing online psychoeducation intervention, the Online Mothers and Babies Course (eMB).
- Trial name
- NCT05867680
- Testing
- Online Mothers and Babies Course (eMB)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Missouri-Columbia
Anxiety Disorders,Generalized Anxiety Disorder
A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder
This is a study in minors (7 to 17 years old) diagnosed with generalized anxiety disorder (GAD) and evaluated using standard questionnaires as having at least moderate severity of GAD.
- Trial name
- NCT03924323
- Testing
- Escitalopram
- Where
- 39 sites in United States
- Volunteers
- 273 people
- Sponsor
- AbbVie
Preoperative Anxiety
Effect of a Preparation Video on Preoperative Anxiety in Children Undergoing Dental Treatment Under GA
The present study investigated the effect of an animated preoperative preparation video in mitigating preoperative anxiety among children receiving comprehensive dental treatment under General Anesthesia (GA).
- Trial name
- NCT06612398
- Testing
- Preoperative preparation video
- Where
- Jordan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Generalized Anxiety, Introspective & Anxiety-Prone Patient
Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.
In France today, it is estimated that one in every 850 people aged between 20 and 45 is a childhood cancer survivor (CCS), equivalent to around 40,000 to 50,000 people.
- Conditions
- Generalized Anxiety, Introspective & Anxiety-Prone Patient, Depression, Anxiety, Survivors of Childhood Cancer
- Trial name
- HARMONY-Tool (NCT07117058)
- Testing
- New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale)
- Where
- 7 sites in France
- Volunteers
- 545 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Generalized Anxiety Disorder
CBT for GAD: Impact of Cognitive Processing on Treatment Outcome
Generalized anxiety disorder (GAD) is a condition characterized by chronic and excessive worry and anxiety. Over the past 15 years, the investigators have developed a cognitive-behavioural treatment that leads to the remission of…
- Trial name
- NCT03099772
- Testing
- CBT-IU
- Volunteers
- 80 people
- Sponsor
- Concordia University, Montreal
Social Anxiety, Generalized Anxiety
Imagery Rescripting and Imaginal Exposure for Anxiety Symptoms
This study will recruit 460 participants who self-report high symptoms of anxiety. Participants will be randomly assigned to one of 4 groups: one analog intervention of Imagery Rescripting (IR) for memories, an analog…
- Conditions
- Social Anxiety, Generalized Anxiety, Obsessive-Compulsive Symptom, Panic
- Trial name
- NCT05292807
- Testing
- Imaginal exposure for memories, Imaginal exposure for future events, Imagery rescripting for memories
- Where
- Israel
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Generalized Anxiety Disorder
Efficacy and Safety of Inhaled NC-107 As Compared to Placebo After 4 Weeks of Treatment in Patients with Anxiety
The goal of this clinical trial is to learn if inhaled drug NC-107 works to treat Generalized anxiety disorder in adults. It will also learn about the safety of the drug NC-107.
- Trial name
- CALM (NCT06656806)
- Testing
- Measure concentrations of CBD in spot urine collections from subjects treated with inhaled CBD, Determine the presence and concentration of CBD in subject's plasma with inhaled CBD
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Trinity Hypertension & Metabolic Research Institute
Dementia, Alzheimer Disease
Effectiveness of a 3-month Individual Reminiscence Therapy Program in Older Adults With Alzheimer's Disease
This research aims to evaluate the effectiveness of individual Reminiscence Therapy (RT) program, using a simple reminiscence format, to improve the overall cognitive function, mood, and quality of life (QoL) of older adults with…
- Conditions
- Dementia, Alzheimer Disease, Cognitive Impairment
- Trial name
- NCT06812442
- Testing
- Reminiscence therapy
- Where
- 4 sites in Portugal
- Volunteers
- 40 people
- Sponsor
- Rsocialform - Geriatria, Lda
Generalized Anxiety Disorder
6-Session Treatment for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a chronic condition that is characterized by excessive and uncontrollable worry and anxiety. In Canada, 3 to 4% of the population suffer from GAD at any point in time.
- Trial name
- NCT03433625
- Testing
- Behavioural experiments for intolerance of uncertainty (BE-IU)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais