Clinical trials: Anxiety, Mild to Moderate
Mild-to-Moderate Stress
Prebiotic Effects on Anxiety, Cortisol, and Emotional Processing in Mild-to-Moderately Stressed Adults
The levels of stress that we experience as a population are continuing to rise due to financial, social and work pressures, particularly in mid-life where additional factors such as family and career often compound these issues.
- Trial name
- PEACE (NCT06991023)
- Testing
- Prebiotic (Bimuno®)
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University of Reading
Anxiety
Pilot Study to Assess the Effect of a Postbiotic Blend on Moderate Self-reported Anxiety
This study evaluates the efficacy of a multistrain postbiotic administered in the form of a capsule in the management of moderate self-reported anxiety in adults aged 18-65
- Trial name
- Anx (NCT05562739)
- Testing
- Postbiotic
- Where
- Ireland
- Volunteers
- 10 people
- Sponsor
- The Archer-Daniels-Midland Company
Depressive Symptoms
EVALUATION OF EFFICACY OF SAMEUP IN SUBJECTS WITH DEPRESSION SYMPTOMS: A RANDOMIZED STUDY
This study is planned to assess the efficacy of SAMEUp versus placebo after six weeks of treatment in subjects characterized by depression symptoms according to ICD-10 (International Classification of Diseases - 10th revision)…
- Trial name
- SAMEUP (NCT03932474)
- Testing
- SAMEUp
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Nutrilinea srl
Anxiety Mild to Moderate, Inhibition (Psychology)
Tiny Heroes Compared to Treatment as Usual to Decrease and Prevent Anxiety Problems in Young Children - a Randomized Controlled Study
The aim of this randomized controlled trial is to evaluate the effectiveness and cost-effectiveness of Tiny Heroes, a parent-directed internet-delivered cognitive behavioral therapy (iCBT) program for anxiety problems in children…
- Trial name
- NCT07870213
- Testing
- Parent-directed online cognitive behavioral therapy, Treatment as Usual (TAU)
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Anxiety, Anxiety and Fear
Effectiveness of a Digital Application for Adolescents With Mild to Moderate Anxiety
The goal of this randomized controlled trial is to investigate the effectiveness of a new therapist-guided rule based intervention in Bergen Municipality, Child and Family help center.
- Conditions
- Anxiety, Anxiety and Fear, Adolescent - Emotional Problem
- Trial name
- NCT06531980
- Testing
- Modi, Treatment as usual
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Haukeland University Hospital
Long-term Physical Health Conditions, Mild to Moderate Anxiety and/or Depression
A Component Analysis of Acceptance and Commitment Therapy
The purpose of this study is to determine whether a specific component of Acceptance and Commitment Therapy (ACT) called 'Self as Context' is an important and necessary part of this therapeutic approach.
- Trial name
- NCT02162030
- Testing
- Acceptance and Commitment Therapy
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Sheffield
Anxiety, Mild to Moderate Depression
Guided Internet-based Interventions in Primary Care Effectiveness-implementation Randomized Controlled Trial
Internet-based cognitive behavioral therapy for anxiety and depression have far-reaching potential to overcome common barriers to accessing evidence-based treatment, such as waiting lists, travel distance and costs.
- Trial name
- INTERMENTAL (NCT05118828)
- Testing
- Guided internet-based cognitive behavioural therapy, Treatment as usual in Prompt Mental Health Care (TAU-PMHC)
- Where
- 6 sites in Norway
- Volunteers
- 1,000 people
- Sponsor
- Norwegian Institute of Public Health
Depression, Anxiety
Mindfulness Based Cognitive Therapy (MBCT) for Primary Care Patients
This study is done to evaluate the effects of Mindfulness Based Cognitive Therapy (MBCT) for primary care patients that have mild to moderate symptoms of depression and anxiety.
- Trial name
- NCT03272516
- Testing
- Mindfulness based cognitive therapy (MBCT), Treatment as usual (TAU)
- Where
- 2 sites in Iceland
- Volunteers
- 120 people
- Sponsor
- University of Iceland
Cognitive Impairment, Alzheimer Disease
Impact of Hypno-analgesia on Pain During a Lumbar Puncture for Diagnosis of Alzheimer's Disease
One of the missions of the Memory of Resources and Research Center (CMRR) is to establish a diagnosis of expertise in patients with amestic, language or behavioral cognitive complaint.
- Trial name
- PLHYMANEDE (NCT03352024)
- Testing
- Relational care, Hypno-analgesia
- Sponsor
- University Hospital, Montpellier
Anxiety, Mild to Moderate, Inhibited Temperament
Tiny Heroes: Decrease and Prevent Anxiety Problems in Young Children
In Sweden, there is a lack of evidence-based methods to reduce and prevent young children's emotional problems, such as worry and anxiety.
- Trial name
- NCT06817304
- Testing
- Tiny Heroes
- Where
- 2 sites in Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska Institutet
Anxiety Disorder, Chronic Myeloproliferative Disorders
Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation
RATIONALE: Music therapy may be effective in relieving pain and emotional distress in patients who are undergoing cancer therapy.
- Conditions
- Anxiety Disorder, Chronic Myeloproliferative Disorders, Depression, Lymphoma
- Trial name
- NCT00014482
- Testing
- pain therapy, psychosocial assessment and care
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
RATIONALE: Ketamine hydrochloride may lessen neuropathic pain in patients with cancer. It is not yet known whether ketamine hydrochloride given together with the best pain management is more effective than a placebo given…
- Trial name
- NCT01316744
- Testing
- ketamine hydrochloride, pharmacogenomic studies, questionnaire administration
- Where
- 3 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Glasgow
Stress, Healthy Subjects
The Effects of Chicory Root-derived Prebiotic on Mood and Stress Responsiveness in Healthy Adults With Mild to Moderate Levels of Stress and Anxiety
Emerging evidence from preclinical research suggests that prebiotic fibres may play a beneficial role in supporting mental health through modulation of the gut-brain axis-a complex communication network linking the…
- Conditions
- Stress, Healthy Subjects, Anxiety, Mild to Moderate
- Trial name
- PRIME (NCT07058324)
- Testing
- Prebiotic fiber
- Where
- Germany
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Anxiety, Anxiety Disorders
A Feasibility Study of Nature-based Health Interventions for People With Mild to Moderate Anxiety, Depression and Stress
Background and aimThe increased burden on mental health both globally and nationally is a serious challenge that requires attention and action from healthcare professionals, politicians, and decision-makers.
- Conditions
- Anxiety, Anxiety Disorders, Depression - Major Depressive Disorder, Depressive Disorder
- Trial name
- NCT06981000
- Testing
- Locally adapted nature-based health intervention
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Copenhagen
Anxiety
Probiotics for Anxiety Study
The purpose of this study is to observe the effect of a consumer-grade probiotic capsule called GABA (gamma-aminobutyric acid ) Probiotic ("Study Product"), a probiotic capsule containing Lactiplantibacillus plantarum 815, on…
- Trial name
- NCT06466603
- Testing
- GABA Probiotic Dose 1, GABA Probiotic Dose 2
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Verb Biotics LLC
Depression, Anxiety Disorders
Investigating Transcranial Ultrasound as a Potential Intervention for Depression
Depression is the leading cause of disability worldwide. Because a significant number of people with depression do not respond to medication or therapy, alternative treatment options are greatly needed.
- Trial name
- NCT02685488
- Testing
- Transcranial Ultrasound Power
- Volunteers
- 26 people
- Sponsor
- University of Arizona
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Depression and/or Anxiety in the Mild-to-moderate Range
Personalized Need-focused Single Session Intervention
This is a two-site randomized controlled trial, with two goals. First, the investigators aim to demonstrate that single-session interventions for mild-to-moderate anxiety and depression can generate statistically significant…
- Trial name
- NCT05953779
- Testing
- Clinician-administered Need-focused Single Session Intervention
- Where
- 2 sites in United States, Israel
- Volunteers
- 240 people
- Sponsor
- Bar-Ilan University, Israel
Preeclampsia Mild to Moderate
The Effect of Awareness-Based Stress Reduction Training on Preeclampsia and Anxiety
Preeclampsia is a multisystem disease that occurs during pregnancy and carries risks into the postpartum period. This condition, which threatens maternal and fetal health, requires close monitoring and good care.
- Trial name
- NCT06841367
- Testing
- Mindfulness-based stress reduction training
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Dementia, Mild Cognitive Impairment
Virtual Chair Yoga for Older Adults and Caregivers: Randomized Controlled Trial
Over 700,000 Canadians are affected by dementia costing the health care system approximately $10 billion/year. Due to COVID-19, the government has urged individuals over the age of 70 to stay home, putting this population at risk…
- Trial name
- NCT04884529
- Testing
- Chair-yoga program
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute