Clinical trials: Anxiety Depression Disorder
Anorexia Nervosa, Obsessive-Compulsive Disorder
Radical Openness for Adolescents Pilot
Heightened performance monitoring and overcontrol (HPM/OC) is characterized by inflexibility, a need for control, perfectionism, anxious apprehension and high error monitoring.
- Conditions
- Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety
- Trial name
- ROA (NCT05913557)
- Testing
- Radically Open Dialectical Behavior Therapy (RO DBT)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Psychological Distress, Anxiety
The Short-term Effects of PRISMA on Mental Health
Given the high prevalence of mental health issues, such as anxiety and depression, in pretrial detainees, the Swiss Federal Justice Department (SFJD) approved a model trial ("Modellversuch Untersuchungshaft", MV).
- Conditions
- Psychological Distress, Anxiety, Depression, Suicidal Ideation
- Trial name
- PRISMA (NCT06197711)
- Testing
- PRISMA
- Where
- Switzerland
- Volunteers
- 1,480 people
- Sponsor
- University of Zurich
Diabetes Mellitus, Depressive Disorder
Precision Mental Health in Diabetes - Subtypes of Mental Health, Trajectories, and Patterns With Glycaemic Control
PRO-MENTAL is a non-interventional, prospective, observational study investigating longitudinal associations between diabetes distress, mental disorders, and glycemic outcomes in people with type 1 diabetes (T1D) and type 2…
- Conditions
- Diabetes Mellitus, Depressive Disorder, Depressive Symptoms, Anxiety Disorders
- Trial name
- PRO-MENTAL (NCT05548699)
- Where
- 2 sites in Germany
- Volunteers
- 1,290 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Pain, Postoperative, Surgical Procedures, Operative
Postoperative Pain in Adult Patients.
Each surgical intervention associated with even a minor tissue injury is a source of pain which needs to be effectively controlled.
- Trial name
- NCT03731039
- Testing
- Observational study
- Where
- Poland
- Volunteers
- 620 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Anxiety, Depression
Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties
Emotion Focused Family Therapy (EFFT) is a promising intervention that aims to teach parents advanced skills to support their child's development of emotion skills and increase their adaptive behaviours, potentially leading to…
- Conditions
- Anxiety, Depression, Behavior Problem
- Trial name
- NCT05603000
- Testing
- Emotion Focused Family Therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Guelph
Depression, Anxiety
Implementation of Brief Dynamic Interpersonal Therapy at the VA
The goal of the proposed project is to collect data from clinician files and the electronic medical record to describe the clinical implementation of Brief Dynamic Interpersonal Therapy (DIT), an individual psychotherapy for…
- Trial name
- DIT (NCT03945136)
- Testing
- Dynamic Interpersonal Therapy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Depression, Anxiety
Depression and Anxiety in the Aetiology and Prognosis of Specific Cardiovascular Disease Syndromes: a CALIBER Study
People report feeling sad and low (depression) or worried (anxiety) appear more likely to subsequently suffer a heart attack, or angina. However it is not known whether depression or anxiety actually causes heart disease.
- Conditions
- Depression, Anxiety, Coronary Disease, Cardiovascular Disease
- Trial name
- NCT01240798
- Where
- United Kingdom
- Sponsor
- University College, London
Depression, Anxiety
Effects of Probiotics on Mood
Recent demonstration that probiotics administration has positive effects on depressive feelings in healthy populations suggests its possible role as an adjuvant therapy for depression in clinical populations and as a non-invasive…
- Trial name
- NCT03539263
- Testing
- Bifihappy
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Probiotical S.p.A.
Mental Health Wellness 1, Depression, Anxiety
Mental Health in Fitness Instructors
The aim of this project is to improve the evidence-base regarding lifestyle and mental health symptoms among fitness instructors.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety, Eating Disorders, Eating Behavior
- Trial name
- NCT04135729
- Where
- Norway
- Volunteers
- 304 people
- Sponsor
- Norwegian School of Sport Sciences
Depression, Anxiety
Cognitive Behavioral Therapy Versus Ericksonian Hypnosis Therapy for Depression and Anxiety Symptoms
Title: Comparison of Cognitive Behavioral Therapy and Ericksonian Hypnosis Therapy for Depression and Anxiety Symptoms; A Controlled Randomized Study. Principal Investigator: Dr.
- Trial name
- NCT06484400
- Testing
- Cognitive Behavioral Therapy, Ericksonian Hypnotehrapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Depression, Anxiety
HIV Engagement and Adolescent Depression Support (HEADS-UP)
This pilot study will individually randomize 105 adolescents living with HIV 1:1:1 to standard of care, adapted intervention, or enhanced intervention.
- Conditions
- Depression, Anxiety, Adolescent Behavior, HIV Infections
- Trial name
- HEADS-UP (NCT06173544)
- Testing
- Standard of Care (SOC), Adapted Friendship Bench (AFB), Enhanced Friendship Bench (EFB)
- Where
- 5 sites in Malawi
- Volunteers
- 106 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Depressive Symptoms
Does a Novel Intervention Targeting Derailment Decrease Depressive Symptoms?
The goal of this clinical trial is to explore the efficacy of a reflective journaling intervention-"Me Through Time"- in decreasing levels of derailment, and its impact on downstream depressive symptoms.
- Conditions
- Depression, Depressive Symptoms, Derailment, Anxiety
- Trial name
- NCT06265701
- Testing
- Derailment-Focused Reflective Journaling, Everyday Tasks Reflective Journaling
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Cornell University
Depression
Collabri Flex - Effect of Collaborative Care for People With Depression in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with depression in general practice, based on past experience gained in the Collabri Project.
- Trial name
- Collabri Flex (NCT03113201)
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 389 people
- Sponsor
- Amager Hospital
Coronary Artery Disease, Coronary Artery Ectasia
Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck…
- Conditions
- Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon, Endothelial Dysfunction
- Trial name
- STRAIN-TIMI (NCT02831153)
- Testing
- coronary angiography
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Ertan YETKIN
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam
Depression, Generalized Anxiety Disorder
A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients
For this trial, the investigators propose a prospective trial of a collaborative care program to identify and treat depression, generalized anxiety disorder, and panic disorder among patients admitted to the hospital for an acute…
- Conditions
- Depression, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- MOSAIC (NCT01201967)
- Testing
- Collaborative care, Usual care
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Massachusetts General Hospital
Cancer Breast, Colon Cancer
The Effect of Acceptance and Commitment Approach-Based Psychoeducation in Cancer Survivors
The study is planned to be conducted in a randomised controlled experimental design in accordance with CONSORT. The study is planned to be conducted between September 2025 and December 2026 at X Hospital with individuals who have…
- Conditions
- Cancer Breast, Colon Cancer, Cancer Survivors
- Trial name
- NCT07205965
- Testing
- Experimental Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Multiple Sclerosis, Nurse's Role
The Effect of Nurse Practitioner (NP-led) Care Upon Mood in People With Multiple Sclerosis
MS is the leading cause of non-traumatic disability in young adults. Canada and Alberta, have the highest prevalence of people with multiple sclerosis (PwMS) in the world.
- Trial name
- NCT04388592
- Testing
- Nurse Practitioner (NP) Led Care Arm
- Where
- Canada
- Volunteers
- 248 people
- Sponsor
- University of Alberta
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Health Care Utilization, Depression
Health and Health Care Utilization Effects of Medical Debt Forgiveness
The goal of this study is to estimate the direct, causal impact of medical debt on health care utilization, mental health, and wellbeing of patients.
- Conditions
- Health Care Utilization, Depression, Anxiety, Subjective Wellbeing
- Trial name
- NCT04835012
- Testing
- Medical debt forgiveness
- Where
- United States
- Volunteers
- 15,008 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
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