Clinical trials: Anxiety Depression Disorder
Anxiety, Depression
Feasibility and Acceptability Trial of a Culturally Adapted Manual Versus Standard CBT Manual: A Randomized Control Trial
This randomized controlled trial (RCT) will compare the efficacy and feasibility and acceptability of a culturally adapted CBT manual with a standard CBT manual, focusing on addressing cultural factors in therapy delivery.
- Trial name
- NCT06646900
- Testing
- Culturally adapted CBT (CaCBT) based guided self-help manual, Standard CBT Manual
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Craving, Depression, Anxiety
Repetitive Transcranial Magnetic Stimulation in Amphetamine Addiction
The study aims to test whether transcranial magnetic stimulation (TMS) improves the craving, depression, anxiety and cognitive function during the abstinent period of methamphetamine users.
- Conditions
- Craving, Depression, Anxiety, Amphetamine Addiction
- Trial name
- NCT04993300
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Anxiety, Depression
Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties
Emotion Focused Family Therapy (EFFT) is a promising intervention that aims to teach parents advanced skills to support their child's development of emotion skills and increase their adaptive behaviours, potentially leading to…
- Conditions
- Anxiety, Depression, Behavior Problem
- Trial name
- NCT05603000
- Testing
- Emotion Focused Family Therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Guelph
Panic Disorder, Generalized Anxiety Disorder
Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project.
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Social Phobia, Obsessive-Compulsive Disorder
- Trial name
- NCT03113175
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 302 people
- Sponsor
- Amager Hospital
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Parkinson Disease
Feasibility of a Behavioural Activation Protocol to Support People With Parkinson's Enhanced by VR
The proposed research project will involve developing and testing the feasibility of a 6 week Behavioural Activation (BA) programme for people with Parkinson's Disease, which will be enhanced by Virtual Reality exercise…
- Trial name
- BAPP-VR (NCT07038603)
- Testing
- BAPP-VR
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Depressive Symptoms, Anxiety
Probiotics, Brain Structure and Psychological Variables
Theory and research on the gut-brain-axis emphasize complex interactions between the gut microbiota, immunological and hormonal responses, brain function, brain structure, as well as resulting behavioral manifestations, such as…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- ProBrain01 (NCT03478527)
- Testing
- Vivomixx® powder
- Where
- Germany
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression, Anxiety
The Efficacy of Cranial Electrostimulating Therapy for Depression and Anxiety Among Homeless Adults
This is a trial of the use of cranial electrostimulating therapy for depression and anxiety among homeless adults.
- Trial name
- NCT02732561
- Testing
- Alpha Stim device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Depression, Anxiety
Impact of Ketamine On Depressive Symptoms In Patients Undergoing Lumbo-peritoneal Shunt Insertion
Postoperative depression is a perioperative psychological complication that severely affects patient recovery and quality of life. In extreme cases, it may lead to suicidal behavior.
- Trial name
- NCT06060210
- Testing
- normal Saline, Ketamine
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Benha University
Depression, Anxiety
Exploring the Role of Online Discussion Forums in Internet-Delivered Therapy for Canadian Public Safety Personnel
This study is a randomized trial designed to evaluate unguided (i.e., purely self-help), transdiagnostic internet-delivered cognitive behavioural therapy tailored specifically for public safety personnel both with and without a…
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT05145582
- Testing
- The Self-Guided PSP Wellbeing Course, Online Discussion Forum
- Where
- 2 sites in Canada
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Regina
Depression, Anxiety, Healthy
Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy)
The aim of this study is to identify biologically viable targets for the treatment of major depressive disorder (MDD) and anxiety disorder (AD) with the ultimate goal of guiding physicians' therapeutic strategies and identifying…
- Trial name
- GAPsy (NCT06167590)
- Testing
- GAPsy protocol
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Depression, Anxiety
Neurofeedback Training For Older Adults
Symptoms of depression and anxiety are common in older adults and are associated with poor outcomes and the risk of dementia. The prefrontal cortex (PFC) is crucial for emotion regulation.
- Trial name
- NCT05936697
- Testing
- fNIRS, EEG, Baseline Training
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Spina Bifida
Evaluation of Depression and Anxiety Levels of Parents of Children with Spina Bifida
Studies in the literature have measured the anxiety and depression levels of parents of children with spina bifida. Additionally, it has been reported that parents of children with non-neurogenic lower urinary tract dysfunction…
- Trial name
- NCT06802770
- Testing
- Anxiety, Depression levels
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Depression, Anxiety
Internet-Delivered Cognitive Behaviour Therapy for Adolescent Depression
The purpose of this study is to determine whether tailored internet-administrated cognitive behaviour therapy (CBT) is a feasible approach in the treatment of depressive symptoms and comorbid anxiety symptoms.
- Trial name
- NCT02363205
- Testing
- Tailored Internet-administrated CBT-Treatment
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Linkoeping University
Anxiety Disorders, Psychotic Disorders
Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness
This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings…
- Conditions
- Anxiety Disorders, Psychotic Disorders, Depressive Disorder, Psychosocial Functioning
- Trial name
- NCT05962879
- Testing
- Resilience Training for Teens
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Stroke, Internet-Delivered Cognitive Behavioural Therapy
ICBT for Persons With Stroke
Despite evidence for ICBT among those with other chronic conditions, its efficacy has yet to be evaluated among those with neurological conditions, including stroke.
- Conditions
- Stroke, Internet-Delivered Cognitive Behavioural Therapy, Depression, Anxiety
- Trial name
- NCT04667754
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms
Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT
This single-blinded, multicentered, randomized controlled trial aims to evaluate the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) in reducing post-traumatic stress…
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms, Anxiety Symptoms, Somatic Symptoms
- Trial name
- TF-CBT (NCT06975280)
- Testing
- Trauma - Focused Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theodora Anastasiou
Hematologic Disease
Anxiety and Depression in Patients With Hematologic Malignancies
Assessment of Anxiety and Depression Status in Patients with Hematologic Malignancies
- Trial name
- NCT07883070
- Testing
- Baseline Anxiety and/or Depression
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Infertility
Psychological Profile of Women With Infertility in Egypt: A Comparative Study
The aim of this study is to determine the prevalence of psychological affection in infertile egyptian women
- Trial name
- NCT02638441
- Testing
- hospital anxiety and depression scale
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Substance Abuse, Executive Dysfunction
Working Memory Training in Adults With Substance Abuse and Executive Function Deficits.
The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse…
- Conditions
- Substance Abuse, Executive Dysfunction, Anxiety, Depression
- Trial name
- NCT02068261
- Testing
- Computerized Cogmed working memory training, Treatment as usual
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Örebro Läns Landsting
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