Clinical trials: Anxiety Depression Disorder
Depression, Anxiety
HIV Engagement and Adolescent Depression Support (HEADS-UP)
This pilot study will individually randomize 105 adolescents living with HIV 1:1:1 to standard of care, adapted intervention, or enhanced intervention.
- Conditions
- Depression, Anxiety, Adolescent Behavior, HIV Infections
- Trial name
- HEADS-UP (NCT06173544)
- Testing
- Standard of Care (SOC), Adapted Friendship Bench (AFB), Enhanced Friendship Bench (EFB)
- Where
- 5 sites in Malawi
- Volunteers
- 106 people
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety, Depressive Symptoms
The Effects of High-intensity Interval Training on Mental Health and Inflammation
The present study investigated the effects of high-intensity interval exercise training and placebo-exercise on mental health and inflammation using a randomized control trial.
- Conditions
- Anxiety, Depressive Symptoms, Inflammation
- Trial name
- NCT04118309
- Testing
- Exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Depression, Anxiety
Evaluating a Mobile App for Students Seeking Care for Depression and Anxiety at Harvard University Health Services
Brief Summary: Background: There is a growing demand for mental health services on college campuses. At the same time there has been a dramatic surge in development of mobile mental health apps.
- Trial name
- NCT03552900
- Testing
- 7cups Mobile App, Bliss
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Harvard University
Neoplasm Metastases
Cognitive Outcome After Gamma Knife Radiosurgery in Patients With Brain Metastases (CAR-Study A)
Stereotactic radiosurgery (SRS) is increasingly applied in patients with brain metastases (BM) and is expected to have less adverse effects on cognitive functioning than Whole Brain Radiation Therapy (WBRT).
- Trial name
- NCT02953756
- Testing
- Gamma Knife radiosurgery
- Where
- Netherlands
- Volunteers
- 92 people
- Sponsor
- Elisabeth-TweeSteden Ziekenhuis
Physical Disability, Depression
Prognostication of Need for Rehabilitation and Special Support in ICU Survivors
Title: PROGnostication of need for REhabilitation and Special Support after Intensive Care Unit Stay - a multinational, observational study Objectives: 1.
- Conditions
- Physical Disability, Depression, Posttraumatic Stress Disorder, Anxiety
- Trial name
- PROGRESS-ICU (NCT02679157)
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 573 people
- Sponsor
- Karolinska University Hospital
Postpartum Depression (PPD), Perinatal Anxiety
Midwife-led Childbirth Review and Psychological Outcomes in New Parents
The aim of this clinical trial is to support psychological well-being and facilitate adjustment to parenthood among postpartum mothers and fathers through a midwife-led childbirth review (MLCR).
- Conditions
- Postpartum Depression (PPD), Perinatal Anxiety, Postpartum Mental Health
- Trial name
- CROWN (NCT07678801)
- Testing
- Midwife-led childbirth review (MLCR)
- Where
- 2 sites in Czechia
- Volunteers
- 1,300 people
- Sponsor
- Charles University, Czech Republic
Anxiety Symptoms, Depressive Symptoms
Psychological Prevention of Internalizing Disorders
The purpose of this study is to determine whether cognitive-behavioral group prevention (CBT-G) for german children is effective and to what extent parental group training moderates outcome.
- Conditions
- Anxiety Symptoms, Depressive Symptoms, Somatoform Symptoms
- Trial name
- NCT00564239
- Testing
- Cognitive Behavioral Group Therapy
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- Philipps University Marburg
Depression, Anxiety
Hippocampal Plasticity of Young Adults With Childhood Adversity
This study investigates the clinical and neural effects of stress management skill building programs for young adults with childhood adversity.
- Trial name
- NCT02816502
- Testing
- Stress Management Skill Building Program A, Stress Management Skill Building Program B
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Mental Health Disorder, Depression
Digital Lifestyle Intervention for Mental Health Among Migrants: Randomized Controlled Trial
Migrant populations experience elevated levels of psychological distress while facing barriers to accessing mental health care. Lifestyle factors such as physical activity, sleep, diet, and social engagement are closely linked to…
- Conditions
- Mental Health Disorder, Depression, Anxiety, Psychological Distress
- Trial name
- LIFT-RCT (NCT07545239)
- Testing
- Digital Lifestyle Intervention
- Volunteers
- 240 people
- Sponsor
- Karolinska Institutet
Depression, Anxiety
Mechanisms of Mindfulness-based Interventions
Mindfulness-based Interventions (MBIs) are a family of standardized cognitive and behavioral therapies that focus on cultivating mindfulness-related skills for improving maladaptive cognitive, emotional, and behavioral processes.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- MBI (NCT03571386)
- Testing
- Mindfulness-based Cognitive Therapy (MBCT), Mindfulness-based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Vanderbilt University Medical Center
Mental Health Issue, Depression, Anxiety
PRIDE - Pilot Trial of an Online Digital Problem-solving Intervention for School-going Adolescents in Goa, India
This study is part of a Wellcome Trust-funded research programme in India called PRIDE (PRemIum for aDolEscents, 2016-2022) led by Principal Investigator Prof. Vikram Patel (Harvard Medical School).
- Conditions
- Mental Health Issue, Depression, Anxiety, Stress
- Trial name
- NCT04672486
- Testing
- POD Adventures
- Where
- India
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Sangath
Cancer Survivors, Anxiety
Pilot Study of Internet-Delivered Psychological Treatment for Cancer Survivors
Negative psychological effects of cancer are common, but cancer survivors are rarely offered structured psychological treatment.
- Conditions
- Cancer Survivors, Anxiety, Depression
- Trial name
- IN-FACT-0 (NCT06046573)
- Testing
- Support and information, Behavioral activation, Systematic exposure with mindfulness training
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Mood Disorder, Neurobehavioral Manifestation
Adolescence, Puberty, and Emotion Regulation
The purpose of this study is to use brain imaging technology to compare how the brains of adolescents and adults are activated during tasks that involve emotional responses.
- Conditions
- Mood Disorder, Neurobehavioral Manifestation, Healthy
- Trial name
- NCT00016731
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Mental Health (NIMH)
HIV Infections, Behavioral Symptoms
Friendship Bench Adaptation to Improve Mental Health & HIV Care Engagement Outcomes Among PLWH and PWID in Vietnam
This project will adapt and pilot a feasible and effective problem-solving therapy designed for low-resource settings to address common mental disorders like depression and anxiety - the Friendship Bench- in a Vietnamese…
- Conditions
- HIV Infections, Behavioral Symptoms, Depression, Anxiety
- Trial name
- VITAL (NCT04790201)
- Testing
- Friendship Bench Delivered by Professional Counselor, Friendship Bench Delivered by Lay Counselor, Enhanced Usual Care
- Where
- Vietnam
- Volunteers
- 77 people
- Sponsor
- University of North Carolina, Chapel Hill
DGBI, Depression/Anxiety
Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction - Beta Trial
The goal of this clinical trial is to assess the acceptability, feasibility, and usability of the iACTforDGBI intervention among patients with Disorders of Gut-Brain Interaction (DGBI).
- Trial name
- iACTforDGBI (NCT07175402)
- Testing
- Acceptance and Commitment Therapy (ACT), Psychoeducation
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- Örebro University, Sweden
PTSD, Autism Spectrum Disorder High-Functioning
Psychiatric Orders in Psychoanalytic Treatment of ASD
Autism Spectrum Disorder (ASD) is often accompanied by a variety of other symptoms, such as bipolar disorder, Attention Deficit Hyperactivity Disorder (ADHD), Social Anxiety Disorder (SAD), Avoidant Personality Disorder (AvPD)…
- Conditions
- PTSD, Autism Spectrum Disorder High-Functioning, OCD, Agoraphobia With Panic Attacks
- Trial name
- NCT05930912
- Testing
- Psychoanalysis, sertraline 50mg, Duloxetine 20 MG
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Yang I. Pachankis, PhD
Cancer Breast, Colon Cancer
The Effect of Acceptance and Commitment Approach-Based Psychoeducation in Cancer Survivors
The study is planned to be conducted in a randomised controlled experimental design in accordance with CONSORT. The study is planned to be conducted between September 2025 and December 2026 at X Hospital with individuals who have…
- Conditions
- Cancer Breast, Colon Cancer, Cancer Survivors
- Trial name
- NCT07205965
- Testing
- Experimental Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Depression, Anxiety
An Outreach Collaborative Model for Early Identification and Treatment of Mental Disorder in Danish Workplaces
Depression and anxiety are prevalent mental disorders among the working population with potentially high personal and financial cost.
- Trial name
- NCT03786328
- Testing
- Standard Psychiatric Treatment, Preventive Psychological Treatment
- Volunteers
- 73 people
- Sponsor
- Helle Østermark Sørensen
Mental Health Issue, Anxiety Disorders
Culture and Well-being: Art as Prescription Therapy ("Art on Prescription")
Stratified randomised controlled trial with two arms: arts intervention (any of the arts interventions, see list), which we call here Active Group (AG) vs waitlist control (WL).
- Conditions
- Mental Health Issue, Anxiety Disorders, Depressive Disorder, Emotional Disorder
- Trial name
- AoP (NCT06361667)
- Testing
- Arts
- Where
- Greece
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- KAVADIA ELENI
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