Clinical trials: Anxiety Depression Disorder
Neural Inhibition, Anxiety
The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms
This clinical trial investigates the effects of Vitamin B6 supplementation on neural inhibition using electroencephalography (EEG), in relation to depression and anxiety symptoms in participants from the general population with a…
- Conditions
- Neural Inhibition, Anxiety, Depression
- Trial name
- NCT07469462
- Testing
- Pyridoxal-5'-Phosphate supplement
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Reading
Crohn Disease, Pain
Pain in Patients With Crohn Disease (PAINCD)
Abdominal pain is a common symptom in patients with Crohn disease (CD). Pain is multifactorial, may result from inflammation but persists in many patients during remission.
- Conditions
- Crohn Disease, Pain, Depression, Anxiety
- Trial name
- PAINCD (NCT04488146)
- Volunteers
- 200 people
- Sponsor
- University of Liege
Chronic Obstructive Pulmonary Disease
Physical Activity Promotion Added to Standard Care Pulmonary Rehabilitation and Cognitive Behavioural Therapy
In patients with Chronic Obstructive Pulmonary Disease (COPD) daily physical activity is reduced compared to healthy age-matched individuals.
- Trial name
- NCT03749655
- Testing
- Physical Activity Promotion
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Northumbria University
Mood Disturbance
Effect of Saffron Extract Supplementation on Emotional Well-being Alterations
This study aims to test whether a saffron extract represents a good candidate to improve emotional well-being in subjects with subclinical symptoms of depression, fatigue, stress or anxiety.
- Trial name
- SAFFROMFOOD (NCT05690126)
- Testing
- Saffron extract, Maltodextrin
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Anxiety, Anxiety Disorders
A Single-session Growth Mindset Intervention for Children and Young People With Mental Health Difficulties
The present study aims to evaluate whether an online, self-administered, single session intervention (SSI) increases children and adolescents' perceptions of control over external threats and their emotional experience and…
- Conditions
- Anxiety, Anxiety Disorders, Depression, Low Mood
- Trial name
- NCT04652362
- Testing
- Growth Mindset Online Single-Session Intervention, Supportive Therapy Online Single-Session Intervention (Control)
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Depression, Anxiety
Efficacy of EMDR in the Treatment of Depression and Comorbid Anxiety
This research is aimed at investigating the efficacy of eye movement desensitization and reprocessing (EMDR) psychotherapy for treating depression and comorbid anxiety symptoms.
- Trial name
- NCT04976413
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) psychotherapy, Counselling as usual
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Quaid-e-Azam University
Colic, Infantile, Crying Time in Colicky Infants
The Effect of Colic Massage and Kangaroo Care on Babies and Their Mothers
Background: Infantile colic is a condition characterized by inconsolable crying in infants under three months of age. Purpose: The aim of this study is to determine the effects of colic massage and kangaroo care on infantile…
- Conditions
- Colic, Infantile, Crying Time in Colicky Infants, Postpartum Depression, Postpartum Anxiety
- Trial name
- randomized (NCT06727760)
- Testing
- massage, kangroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gulsah Sunay Ertem
Suicidal Ideation, Social Behavior
Massive Mental Health Screening Using Smartphones in 24 Pre-graduate Education Centers in Mexico City: TEDUCA Survey Protocol
The objective of this study is to make a massive suicide risk and social behavior assessment in 24 pre-graduate education centers in Mexico City (approximately 30,000 students aged between 15 and 22 years), taking also into…
- Conditions
- Suicidal Ideation, Social Behavior, Depression, Depressive Disorder
- Trial name
- TEDUCA (NCT04067076)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 30,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Psoriatic Arthritis
Study Evaluating Anxiety and Depression in Patients With Psoriatic Arthritis
This is an epidemiological non-interventional study assessing the prevalence of anxiety and/or depression disorders in patients suffering from Psoriatic Arthritis (PsA) in Spain.
- Trial name
- NCT00884468
- Where
- Spain
- Volunteers
- 384 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Bipolar Disorder
Evaluation of the Genetics of Bipolar Disorder
This study looks to identify genes that may affect a person's chances of developing bipolar disorder (BP) and related conditions.
- Trial name
- NCT00001174
- Where
- United States
- Volunteers
- 4,210 people
- Sponsor
- National Institute of Mental Health (NIMH)
Mental Health Issue, Depression, Anxiety
A Study on Young Individuals' Mental Health in Sweden
The goal of this observational study is to increase our knowledge about the mental health of young individuals and to establish a valid and comprehensive method for assessing mental health in young individuals (15-29 years) that…
- Conditions
- Mental Health Issue, Depression, Anxiety, Well-Being, Psychological
- Trial name
- UPIC (NCT06490120)
- Testing
- sampling method
- Where
- Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cardiovascular Disease
Prevention and Treatment of Cardiovascular Disease
In view of the close interrelationship between the various organs and systems of the body, which cannot be examined in a parceled fashion but rather as an integrated system, this study aims to consider the potential risks…
- Trial name
- VPC (NCT06413823)
- Where
- Italy
- Volunteers
- 218 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
LLM-based AI Dialogue Bot, Depression
Young People Aged 18-25 With Depression or Anxiety Mood Participate in an LLM-based Digital Dialogue Intervention Study
This study is a 28-day randomized controlled trial (RCT). Residents were randomly assigned to an intervention group or a waiting group according to the order in which they were successfully contacted by the staff, and each user…
- Conditions
- LLM-based AI Dialogue Bot, Depression, Anxiety
- Trial name
- NCT06346496
- Testing
- Douyin Xinqing AI dialog bot, Douyin Xinqing AI dialog bot for delayed intervention
- Where
- China
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- Institute of Psychology, Chinese Academy of Sciences
Anxiety, Depression
Metacognitive Therapy for Common Mental Health Problems in Autistic CYP: A Case Series
Anxiety and Depression are common in young people (CYP) and especially in CYP with a diagnosis of Autism. Autistic people often say therapy has not been adapted to meet their needs.
- Trial name
- NCT05980143
- Testing
- Metacognitive Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Caregivers
Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being
The purpose of this study is to test whether personalized messages from an easy-to-use mobile app improve mood and stress among care partners and to see if care partners like using the app.
- Trial name
- NCT04556591
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Caregiver Distress
Reducing Distress in Phase 1 Trial Caregivers: The P1-CaLL Study
This study seeks to decrease distress in the lives of the caregivers who are helping cancer patients who have entered a phase 1 clinical trial.
- Trial name
- NCT03557515
- Testing
- Stress Management and CBT, Stress Management and Metta-Meditation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anxiety Disorder, Depression
Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
This trial is designed to test the efficacy of fluoxetine to improve patient's quality of life during chemotherapy. An innovative application of a selective serotonin reuptake inhibitor may modulate the effects of fatigue…
- Conditions
- Anxiety Disorder, Depression, Fatigue, Lung Cancer
- Trial name
- NCT00005850
- Testing
- cisplatin, fluoxetine, gemcitabine hydrochloride
- Where
- 43 sites in United States, Puerto Rico
- Volunteers
- 21 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Psychotic Disorders, ADHD
Cognitive Remediation in Forensic Mental Health Care
Forensic patients often display cognitive deficits, particularly in the domain of executive functions, that represent a challenge to forensic rehabilitation.
- Conditions
- Psychotic Disorders, ADHD, TBI (Traumatic Brain Injury), Aggression
- Trial name
- CRFMHC (NCT04610697)
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Hormone Care, Mild Depression
Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone Care
The purpose of this study is to test whether the peer support program is acceptable, possible, and can improve mental health among individuals accessing hormone care.
- Conditions
- Hormone Care, Mild Depression, Anxiety
- Trial name
- NCT07354113
- Testing
- Peer support group, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder
A Head-to-head Comparison of Virtual Reality Treatment for Post Traumatic Stress Disorder
Therapy that uses Virtual Reality (VR) has been shown to help in the treatment of Post Traumatic Stress Disorder (PTSD). It is unclear what role the VR simulator itself plays in recovery.
- Trial name
- NCT00978484
- Testing
- Virtual Reality Exposure Therapy - Dynamic, Augmented Exposure Therapy
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- United States Naval Medical Center, San Diego
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