Clinical trials: Anxiety Disorders
Obsessive-Compulsive Disorder
The Use of Magnetic Brain Stimulation to Treat Obsessive Compulsive Disorder, a Pilot Study
The purpose of this study is two-fold: first, to observe the effect of one session of repetitive transcranial magnetic stimulation (rTMS) on the error-prediction abilities of patients with obsessive compulsive disorder (OCD) as…
- Trial name
- NCT02541812
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Anxiety Sensitivity, Functional Impairment
BEAST: A Pilot Trial
This pilot study trial will test the acceptability, feasibility, and usability of a brief enhanced anxiety sensitivity treatment to reduce anxiety sensitivity and functional impairment in Veterans.
- Trial name
- BEAST (NCT05416203)
- Testing
- Brief Enhanced Anxiety Sensitivity Treatment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Parkinson Disease
A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease
The major purpose of this study is to assess the efficacy of CBD on motor symptoms of Parkinson's Disease (PD), and secondarily to study the safety and tolerability of CBD and other efficacy, particularly regarding tremor in PD.
- Trial name
- NCT03582137
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Colorado, Denver
Depression, Anxiety
IntelliCare in College Students - Implementation (ICCS-I)
This study is a hybrid effectiveness-implementation trial of the smartphone student stress-management app IntelliCare for college students.
- Trial name
- NCT04108429
- Testing
- IntelliCare for College Students
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Anxiety Disorder, Depressive Disorder
Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children
American Indians (AI) are at greater risk for anxiety and depression early in life. This is concerning given the potential negative effects of these conditions across the lifespan (substance use, suicide).
- Trial name
- NCT05371665
- Testing
- Culturally Adapted Cognitive-Behavioral Prevention and Early Intervention (PEI) Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Montana State University
Depression, Postpartum, Efficacy, Self
A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care
The purpose of this study is to assess the effectiveness of a parenting intervention+usual care compared to usual care on postpartum depression and other mental health and parenting outcomes, as well as the feasibility and…
- Conditions
- Depression, Postpartum, Efficacy, Self, Anxiety
- Trial name
- MInD (NCT04998721)
- Testing
- Promoting First Relationships-Brief, Perinatal Integrated Care
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Treatment of Induced Panic Attack
Staccato Alprazolam in Panic Attack
We are developing Staccato™ Alprazolam for the treatment of Panic attacks associated with panic disorder. This study will provide an initial assessment of efficacy, and to continue to describe the tolerability and…
- Trial name
- NCT00477451
- Testing
- Inhaled alprazolam 1 mg, Inhaled alprazolam 2 mg, IV doxapram
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alexza Pharmaceuticals, Inc.
Depression, Addiction
Providing Mental Health Precision Treatment
This research study is being conducted to understand if patients benefit from mobile health interventions while waiting for in-clinic mental health treatments, and to understand which patients receive the most benefit.
- Conditions
- Depression, Addiction, Anxiety, Sleep Disturbance
- Trial name
- PROMPT (NCT04342494)
- Testing
- Enhanced Feedback + Standard Feedback, Headspace app + Standard Feedback, Headspace app + Enhanced Feedback + Standard Feedback
- Where
- United States
- Volunteers
- 2,118 people
- Sponsor
- University of Michigan
Anxiety, Pain
Lavender Aromatherapy for Anxiety During Urodynamics
Urodynamics are performed in the evaluation of urinary incontinence in women considering surgery or who have failed conservative therapies.
- Trial name
- NCT02344745
- Testing
- Lavandula angustifolia essential oil (Aura Cacia), Distilled water
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Southern California
Trichotillomania
Naltrexone in the Treatment of Trichotillomania
This is an 8-week, double-blind study of Natrexone in the treatment of trichotillomania
- Trial name
- NCT00775229
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Chicago
Hoarding Disorder
Imaginal Exposure for Hoarding Disorder
The present study will test a potential new treatment strategy, imaginal exposure, for hoarding disorder. Although cognitive behavioral therapy often reduces hoarding, some people do not want to start, or cannot handle, that…
- Trial name
- NCT03734705
- Testing
- Imaginal Exposure Writing, Neutral Writing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stanford University
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Mood Disorder, Anxiety Disorders
Intranasal Administration of Neuropeptide Y in Healthy Male Volunteers
There is growing evidence that neuropeptides act as neuronal messengers in the brain and have diverse functions that may include the regulation of mood and behavior.
- Trial name
- NPY (NCT00748956)
- Testing
- Low dose NPY, High dose NPY
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dennis Charney
Anxiety, Lacerations
Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Laceration repair can cause significant anxiety in children. As open wounds account for 21-25% of injuries in children presenting to the emergency department, the management of anxiety is of great importance.
- Trial name
- NCT02618772
- Testing
- Midazolam, Saline
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Depression, Anxiety
The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and Insomnia
The study examined the effects of adding the sleep aid eszopiclone to Lexapro on mood and levels of the neurotransmitters glutamate, glutamine, and GABA in women with depression, anxiety, and insomnia.
- Conditions
- Depression, Anxiety, Insomnia
- Trial name
- NCT00826111
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Post-Traumatic Stress Disorder
Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.
- Trial name
- NCT00739765
- Testing
- Interpersonal Psychotherapy, Prolonged Exposure Therapy, Relaxation Therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- New York State Psychiatric Institute
Delirium, Cognitive Impairment
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
The purpose of this study is to investigate the effectiveness of a preventative low-dose of Haloperidol to prevent delirium in patients undergoing a esophagectomy, pneumonectomy or thoracotomy.
- Conditions
- Delirium, Cognitive Impairment, Post-traumatic Stress Disorder, Depression
- Trial name
- PE-POD (NCT02213900)
- Testing
- Haloperidol
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Indiana University
Generalized Anxiety Disorder
Safety, Efficacy and Tolerability of Vilazodone in Patients With Generalized Anxiety Disorder
The purpose of this study is to evaluate the efficacy, safety, and tolerability of vilazodone relative to placebo in the treatment of generalized anxiety disorder (GAD).
- Trial name
- VLZ-MD-06 (NCT01766401)
- Testing
- Vilazadone
- Where
- 30 sites in United States
- Volunteers
- 402 people
- Sponsor
- Forest Laboratories
Generalized Anxiety Disorder, Panic Disorder
Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSRI or SNRI to Treatment With an SSRI or SNRI Alone in Subjects With Generalized Anxiety Disorder or Panic Disorder
An 8-week, open-label trial in 848 subjects at 212 sites to compare time to response in symptoms of anxiety in subjects treated with Niravam™ and a newly prescribed Selective Serotonin Reuptake Inhibitor (SSRI)or Serotonin and…
- Trial name
- NCT00266409
- Testing
- Niravam, SSRI/SNRI
- Where
- United States
- Volunteers
- 418 people
- Sponsor
- UCB Pharma
Anxiety, Depression
Efficacy of CES in New Mothers During the Post Partum Period
The birth of a child is a major life event that can be filled with excitement, anticipation and joy. However, the transition and adaptation to new demands, roles, responsibilities, and changes in relationships can be stressful…
- Conditions
- Anxiety, Depression, Insomnia, Sleep Quality
- Trial name
- NCT03210155
- Testing
- Alpha-Stim AID CES (Active Comparator)
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Christina Murphey, RN, PhD