Clinical trials: Anxiety Symptoms
Obsessive-Compulsive Disorder
Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)
The most common and effective treatment for OCD is pharmacological therapy that includes selective serotonin reuptake inhibitors (SSRIs) antidepressants and, in the case of patients resistant to this approach, a combination with…
- Trial name
- OCD-RT (NCT06611592)
- Testing
- Pramipexole 0.088mg/tid, Pramipexole 0.18 mg/tid, Pramipexole 0.35 mg/tid
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Anxiety
Pre-procedural Anxiety and Sedation.
Colonoscopy is an outpatient procedure performed frequently as a screening test for diagnosis and treatment of a wide range of gastrointestinal problems.
- Trial name
- NCT01958151
- Testing
- State-Trait Anxiety Inventory Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Basak Ceyda MECO
Anxiety Disorders, Mindfulness
The Impact of Mindfulness-Based Psychoeducation on Perceived Stress, Intolerance of Uncertainty, and Cognitive Flexibility in Patients With Anxiety Disorders
Mindfulness-based interventions, which cultivate the capacity to remain present with difficult thoughts and emotions and to maintain psychological well-being in the face of such challenges, have been shown to facilitate positive…
- Conditions
- Anxiety Disorders, Mindfulness, Perceived Stress, Intolerance of Uncertainty
- Trial name
- Anxiety (NCT07299045)
- Testing
- Mindfulness-Based Psychoeducational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aydin Adnan Menderes University
Dental Anxiety
The Effect of a Preparation Video Using " Cartoon Animated Video Modeling" on Preoperative Anxiety Among Pre-School Children During The First Dental Visit: A Randomized Clinical Trial
The primary aim of this study is to evaluate the efficacy of cartoon animated video-modeling in reducing preoperative anxiety among pre-school children during the first dental visit.
- Trial name
- NCT07715539
- Testing
- Video modelling group
- Where
- Jordan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Anxiety State
Evaluation of an Anxiety Reduction Tool During Thyroid Biopsies
Patients undergoing thyroid biopsy under local anesthetic will be asked to fill out a questionnaire that evaluates their anxiety level before and after their procedure.
- Trial name
- NCT06358612
- Testing
- Stress Balls
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Nova Scotia Health Authority
Parkinsons Disease (PD), Anxiety
TMS in Anxiety-Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's dementia. Anxiety in PD is common, has major effects on quality of life and contributes to increased disability.
- Trial name
- NCT06999330
- Testing
- Theta burst stimulation active coil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HealthPartners Institute
Non-infectious Uveitis
Mindfulness Approach for Reducing Anxiety and Gloom in Ocular Inflammatory Diseases
The proposed study is a block-randomized, controlled trial to evaluate the effects of a digital meditation and mindfulness practice on mental health in patients with non-infectious uveitis.
- Trial name
- MARiGOLD (NCT06585670)
- Testing
- Calm Health - smartphone application
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Generalized Anxiety Disorder
Randomized Trial of Adult Participants With Generalized Anxiety Disorder
The purpose of this study is to compare the efficacy of troriluzole versus placebo in participants with generalized anxiety disorder.
- Trial name
- NCT03829241
- Testing
- Troriluzole
- Where
- 53 sites in United States
- Volunteers
- 881 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Anxiety Disorder
Association of Passiflora Incarnata L; Crataegus Oxyacantha L and Salix Alba L. on Mild and Moderate Anxiety
Phase III, multicentric, double blind, randomized study, controlled by Valeriana officinalis for evaluating the efficacy of association of Passiflora incarnata L; Crataegus Oxyacantha L and Salix alba L.
- Trial name
- NCT00794456
- Testing
- Passiflora ; Crataegus and Salix, Valeriana
- Where
- 2 sites in Brazil
- Volunteers
- 150 people
- Sponsor
- Marjan Industria e Comercio ltda
Depression, Anxiety
REstoring Mental Health Through COmmUnity-based Psychological Services in New York City
The goal is to improve mental health. The study will evaluate the impact of community-based mental health services. Successful completion of this study will contribute to the National Institute of Mental Health Strategic Plan…
- Conditions
- Depression, Anxiety, Psychological Distress, PTSD
- Trial name
- RECOUP-NY (NCT04913766)
- Testing
- Problem Management Plus, Services as Usual
- Where
- United States
- Volunteers
- 1,206 people
- Sponsor
- George Washington University
Intrauterine Insemination
A Study of Music Therapy to Support Intrauterine Insemination
The purpose of this research is to learn if playing music in the room during an intrauterine insemination procedure decreases anxiety and pain for patients at the time of the procedure.
- Trial name
- NCT05492331
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mental Health, Psychological Trauma
Pathway-Matched Resilience-Oriented Therapy in Rwanda
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (RoT), a culturally adapted group-based psychosocial intervention for post-genocide Rwanda.
- Conditions
- Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression
- Trial name
- RoT-CRT (NCT07621731)
- Testing
- Resilience-Oriented Therapy - Emotion-Regulation Variant, Resilience-Oriented Therapy - Identity-Development Variant, Resilience-Oriented Therapy - Behavioural Self-Management Variant
- Where
- 5 sites in Rwanda
- Volunteers
- 427 people
- Sponsor
- Alexandros Lordos, PhD
Anxiety Disorders
Emotion Detectives In-Out: Feasibility and Efficacy of a Blended Version of the Unified Protocol for Children
The goal of this clinical trial is to test the efficacy of a blended format (i.e., a combination of face-to-face and online sessions into one integrated treatment protocol) of the Unified Protocol for Transdiagnostic Treatment of…
- Trial name
- NCT05747131
- Testing
- Emotion Detectives In-Out, Coping Cat
- Where
- 2 sites in Portugal
- Volunteers
- 180 people
- Sponsor
- University of Coimbra
Obsessive-Compulsive Disorder
Modulating Prefrontal Circuits Underlying Behavioral Flexibility in OCD: A TMS Study
This study investigates whether slow-frequency repetitive transcranial magnetic stimulation targeting frontal pole can acutely modulate brain circuits which show abnormal functioning during behavioral flexibility in…
- Trial name
- NCT04165577
- Testing
- rTMS
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Preventive Intervention
Preventive Intervention to Promote Healthy Ageing
The aim of the project is the support of healthy ageing of older adults in acommunity. Efficient educational and psychosocial intervention will besuggested and verified to prevent anxiety, depression, and cognitivedisorders of…
- Trial name
- NCT05637177
- Testing
- Anging Wisely, Music therapy, Reminiscence therapy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Dental Anxiety, Pain
Dental Anxiety and Pain During Inferior Alveolar Nerve Block in Children: the Effects of Two Distraction Techniques
Objectives: To compare the effectiveness of virtual reality (VR) and external cooling and vibration distraction techniques on dental anxiety and pain in children during inferior alveolar nerve block (IANB).
- Conditions
- Dental Anxiety, Pain, Distraction Methods, Local Anesthesia
- Trial name
- NCT06788301
- Testing
- Inferior Alveolar Nerve Block, VR eyeglasses, Buzzy device
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Anxiety, Depression
Effect of Aerobic Training on Asthmatic Patients
The investigators hypothesize that aerobic training can reduce anxiety, depression and airway inflammation and those benefits may be related to changes in autonomic system.
- Conditions
- Anxiety, Depression, Airway Inflammation
- Trial name
- NCT00989365
- Testing
- Aerobic training
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Autism Spectrum Disorder, Anxiety
A Pilot Study of Buspirone for the Treatment of Anxiety in Youth with Autism Spectrum Disorders
The main objective of this exploratory 8-week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT03432065
- Testing
- Buspirone
- Sponsor
- Massachusetts General Hospital
Anxiety
Attention Bias Modification Training in Youth With Subthreshold Impairing Anxiety
This study is a pilot test of Attention Bias Modification Training (ABMT) among clinic referred children and adolescents with subthreshold impairing anxiety (i.e., anxiety and related impairment that fails to meet criteria for an…
- Trial name
- NCT02410967
- Testing
- Attention Bias Modification
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Florida International University
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